KEGG   Mycobacterium lentiflavum: MJO58_08590
Entry
MJO58_08590       CDS       T08800                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
mlw  Mycobacterium lentiflavum
Pathway
mlw00290  Valine, leucine and isoleucine biosynthesis
mlw00660  C5-Branched dibasic acid metabolism
mlw01100  Metabolic pathways
mlw01110  Biosynthesis of secondary metabolites
mlw01210  2-Oxocarboxylic acid metabolism
mlw01230  Biosynthesis of amino acids
Module
mlw_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:mlw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    MJO58_08590 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    MJO58_08590 (leuC)
Enzymes [BR:mlw01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     MJO58_08590 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     MJO58_08590 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX_3rd
Other DBs
NCBI-ProteinID: ULP43981
UniProt: A0ABY3V023
LinkDB
Position
1768821..1770269
AA seq 482 aa
METTERQRPGGKPRTLAEKVWDDHVVVSGSTGEGAGAPDLIYIDLHLVHEVTSPQAFDGL
RLAGRPVHRPDLTIATEDHNVPTVDIDKPIADPISRTQVETLRRNCAEFGVRLHPMGDID
QGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFK
TMAVNVDGELPPGVTAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTVCNMSI
EAGARAGMVAPDETTYEFLRGRPHAPTGAQWDAALQYWRQLRTDDGAAFDTEVHLDAASL
TPFVTWGTNPGQGVPLGAAVPDPELMTNDDERQAAEKALAYMDLRPGMPMRDIAVDTVFV
GSCTNGRIEDLRMVADVLRGRTVARGVRMLVVPGSMRVRAQAEAEGLSAVFTAAGAEWRQ
AGCSMCLGMNPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSTPAD
LN
NT seq 1449 nt   +upstreamnt  +downstreamnt
atggaaaccaccgagaggcagcgaccaggcggaaagccgcgcaccctggccgaaaaggtt
tgggacgaccacgttgtggtatccggctcgacaggtgagggggccggagcgcccgacttg
atttacatcgacctgcatttggtgcacgaggtcaccagcccgcaggcgtttgacggcctg
cgcctggctggtcgcccggtgcaccggccggatctgacgatcgccaccgaggaccacaac
gtgccgaccgtcgacatcgacaagccgatcgccgacccgatatcgcgcacccaggtcgag
acattgcggcgcaactgcgcggaattcggtgtgcggttgcatccgatgggcgacatcgat
cagggcatcgtgcatgtcgtcggaccccaattggggctgacccaaccgggaatgacgatt
gtgtgtggggacagtcacacgtccacccatggtgcattcggcgcactggcgatgggcatc
ggcacctcggaggtcgagcatgtgctggccacccagacattgccgttgcgccccttcaag
acaatggcggtcaacgtcgacggcgaattaccgcccggtgttacggccaaggacatcatc
ctcgcgctgatcgccaagatcggcaccggcggtgggcagggccatgtcatcgaataccgg
ggcagcgcgatcgaatcgctgtccatggaaggccggatgacggtctgcaacatgagtatc
gaggccggggcgcgggccggaatggtggccccggacgagaccacctatgaattcctgcgg
ggtcgcccgcacgcgccgaccggtgcccagtgggacgccgcgttgcagtattggcgacag
ctgcgcaccgacgacggtgccgccttcgacaccgaggtccatctggacgcggcgtcgttg
accccgttcgtcacctggggcactaatccgggccagggcgtgccgttgggagctgcggtg
cccgaccccgaattgatgaccaacgacgacgagcggcaggccgccgagaaagcgttggcg
tatatggaccttcggccgggcatgccgatgcgcgacatcgccgtcgacacggtattcgtc
gggtcttgcaccaacggccgtatcgaagatctgcgcatggtggccgacgtgctgcgcggg
cgcacggtggcccggggggtacgaatgctggtcgtgccgggctcgatgcgggtgcgcgcg
caagccgaagccgaaggcctcagtgcggtattcaccgccgccggcgccgaatggcggcag
gccggctgctcgatgtgcctgggcatgaaccccgatcagcttgcgcccggcgagcgttgc
gccgcgacgtccaaccgcaacttcgaagggcggcagggcaaaggcggccgtacgcatttg
gtatcgccggccgtcgcggcggcaaccgcggtccgcggcacattgtctaccccggccgac
ttgaactga

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