KEGG   Mirounga leonina (Southern elephant seal): 117998657
Entry
117998657         CDS       T07472                                 
Symbol
ATF4
Name
(RefSeq) cyclic AMP-dependent transcription factor ATF-4
  KO
K04374  cyclic AMP-dependent transcription factor ATF-4
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04022  cGMP-PKG signaling pathway
mlx04137  Mitophagy - animal
mlx04141  Protein processing in endoplasmic reticulum
mlx04151  PI3K-Akt signaling pathway
mlx04210  Apoptosis
mlx04211  Longevity regulating pathway
mlx04261  Adrenergic signaling in cardiomyocytes
mlx04668  TNF signaling pathway
mlx04720  Long-term potentiation
mlx04722  Neurotrophin signaling pathway
mlx04725  Cholinergic synapse
mlx04728  Dopaminergic synapse
mlx04911  Insulin secretion
mlx04912  GnRH signaling pathway
mlx04915  Estrogen signaling pathway
mlx04918  Thyroid hormone synthesis
mlx04922  Glucagon signaling pathway
mlx04925  Aldosterone synthesis and secretion
mlx04926  Relaxin signaling pathway
mlx04927  Cortisol synthesis and secretion
mlx04928  Parathyroid hormone synthesis, secretion and action
mlx04932  Non-alcoholic fatty liver disease
mlx04934  Cushing syndrome
mlx04935  Growth hormone synthesis, secretion and action
mlx05010  Alzheimer disease
mlx05012  Parkinson disease
mlx05014  Amyotrophic lateral sclerosis
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05030  Cocaine addiction
mlx05031  Amphetamine addiction
mlx05034  Alcoholism
mlx05161  Hepatitis B
mlx05163  Human cytomegalovirus infection
mlx05166  Human T-cell leukemia virus 1 infection
mlx05203  Viral carcinogenesis
mlx05207  Chemical carcinogenesis - receptor activation
mlx05215  Prostate cancer
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    117998657 (ATF4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    117998657 (ATF4)
   04668 TNF signaling pathway
    117998657 (ATF4)
   04022 cGMP-PKG signaling pathway
    117998657 (ATF4)
   04151 PI3K-Akt signaling pathway
    117998657 (ATF4)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    117998657 (ATF4)
  09143 Cell growth and death
   04210 Apoptosis
    117998657 (ATF4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    117998657 (ATF4)
   04922 Glucagon signaling pathway
    117998657 (ATF4)
   04912 GnRH signaling pathway
    117998657 (ATF4)
   04915 Estrogen signaling pathway
    117998657 (ATF4)
   04926 Relaxin signaling pathway
    117998657 (ATF4)
   04935 Growth hormone synthesis, secretion and action
    117998657 (ATF4)
   04918 Thyroid hormone synthesis
    117998657 (ATF4)
   04928 Parathyroid hormone synthesis, secretion and action
    117998657 (ATF4)
   04925 Aldosterone synthesis and secretion
    117998657 (ATF4)
   04927 Cortisol synthesis and secretion
    117998657 (ATF4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    117998657 (ATF4)
  09156 Nervous system
   04725 Cholinergic synapse
    117998657 (ATF4)
   04728 Dopaminergic synapse
    117998657 (ATF4)
   04720 Long-term potentiation
    117998657 (ATF4)
   04722 Neurotrophin signaling pathway
    117998657 (ATF4)
  09149 Aging
   04211 Longevity regulating pathway
    117998657 (ATF4)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    117998657 (ATF4)
   05203 Viral carcinogenesis
    117998657 (ATF4)
  09162 Cancer: specific types
   05215 Prostate cancer
    117998657 (ATF4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    117998657 (ATF4)
   05161 Hepatitis B
    117998657 (ATF4)
   05163 Human cytomegalovirus infection
    117998657 (ATF4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    117998657 (ATF4)
   05012 Parkinson disease
    117998657 (ATF4)
   05014 Amyotrophic lateral sclerosis
    117998657 (ATF4)
   05020 Prion disease
    117998657 (ATF4)
   05022 Pathways of neurodegeneration - multiple diseases
    117998657 (ATF4)
  09165 Substance dependence
   05030 Cocaine addiction
    117998657 (ATF4)
   05031 Amphetamine addiction
    117998657 (ATF4)
   05034 Alcoholism
    117998657 (ATF4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    117998657 (ATF4)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    117998657 (ATF4)
   04934 Cushing syndrome
    117998657 (ATF4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mlx03000]
    117998657 (ATF4)
Transcription factors [BR:mlx03000]
 Eukaryotic type
  Basic leucine zipper (bZIP)
   AP-1(-like) components, CRE-BP/ATF
    117998657 (ATF4)
SSDB
Motif
Pfam: bZIP_1 bZIP_2 DUF4407 MCU Nop53 AAA_13 DUF745 DUF3450 bZIP_Maf Asd-4 OVT1 KIF21A
Other DBs
NCBI-GeneID: 117998657
NCBI-ProteinID: XP_034843360
LinkDB
Position
Unknown
AA seq 351 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSE
WLAVDGLVSASDNGKEDAFSGTDWMVEKMDLKEFDFDSLFSIDDLETMPDELLATLDDTC
DLFDPLVQETNKEPPQTVNPIGHLPESLQKTDQIAPFTFLQPLPLSPGALSSTPDHSFSL
ELGSEVDISEGDRKSDSATYSNVIPQCIKEEDAPSDNDSGICMSPESYLGSPQHSPSTSR
GSPNRSLLSPGSLSGSARPKPYDPPGEKTEAKVKVEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTGECKELEKQNEALKERADSLAKEIQYLKDLIEEVRKAREKKRVP
NT seq 1056 nt   +upstreamnt  +downstreamnt
atggccgagatgagtttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggctgaggaaagcctgggtctcttagacgactacctggaggtg
gccaagcacttcaaacctcatgggttctccagcgacaaggctaaggcgggctcctccgaa
tggctggctgtggatgggttggtcagtgcctcagacaacggcaaggaggatgccttctcc
gggacagattggatggtggagaaaatggatctgaaggagtttgattttgattctctgttc
agtatagatgacctggaaaccatgccagatgagcttttggccacgttggatgacacgtgt
gatctctttgaccccctagtccaggagactaataaggagcccccccagactgtgaaccca
attggccatcttccagaaagtttacaaaaaacagaccagattgccccctttaccttcctc
caaccacttcccctctccccaggggccctgtcctccactccagatcattcctttagttta
gagctaggcagtgaagtggatatttcagaaggagatagaaagtcagactccgccacttac
agtaacgtgatccctcagtgcatcaaggaggaggatgccccctcagataatgatagtggc
atctgtatgagtcctgagtcctatctggggtccccccagcatagcccctctacctccagg
ggctctccaaataggagcctgctgtctccaggttccctctctggttctgcccgccccaaa
ccctatgaccctcctggagagaagacagaagcgaaggtaaaggtggagaaactagataag
aagctgaaaaaaatggagcagaacaagacagcagccactcggtaccgccagaagaagagg
gctgagcaggaggccctcactggggagtgtaaagagctggaaaagcagaatgaggctctg
aaagagagggcagattctttagccaaggagatccagtatctgaaagatttgatagaagag
gtccgaaaggcgagggagaagaaaagggtcccctag

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