Mirounga leonina (Southern elephant seal): 117999657
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Entry
117999657 CDS
T07472
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04148
Efferocytosis
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04380
Osteoclast differentiation
mlx04919
Thyroid hormone signaling pathway
mlx04972
Pancreatic secretion
mlx05010
Alzheimer disease
mlx05017
Spinocerebellar ataxia
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
mlx05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
117999657 (ATP2A1)
04024 cAMP signaling pathway
117999657 (ATP2A1)
04022 cGMP-PKG signaling pathway
117999657 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
117999657 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
117999657 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
117999657 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
117999657 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
117999657 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
117999657 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
117999657 (ATP2A1)
05017 Spinocerebellar ataxia
117999657 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
117999657 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
117999657 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
117999657 (ATP2A1)
05414 Dilated cardiomyopathy
117999657 (ATP2A1)
05415 Diabetic cardiomyopathy
117999657 (ATP2A1)
Enzymes [BR:
mlx01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
117999657 (ATP2A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
117999657
NCBI-ProteinID:
XP_034844885
LinkDB
All DBs
Position
Unknown
AA seq
1000 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETTGLSPDQVKRHLEKYGPNELPTEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILTIKSTTLRVDQSIL
TGESISVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGNICVLNEFSITGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTDVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KDKILSVIKEWGTGRDTLRCLALATRDTPPKREEMILEDSAKFMEYETDLTFIGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYADDGPHVTYSQLTHFMQCNEENPDFEGLDCEVFEASEPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLQA
LDLTHWLMVLKISFPVIVLDELLKFVARNYLEDPEDERRK
NT seq
3003 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggccttagcccggaccaagtgaagcggcatctggagaaatacggccccaatgag
ctccctactgaagaagggaagtccctgtgggagttggtggtagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttccttcgtgctggcctggtttgaggaa
ggcgaagagaccatcactgcctttgtggaaccctttgtcatcctcttgatcctcattgcc
aacgccatcgtgggggtttggcaggagcgtaatgcagagaatgccatcgaggctttgaag
gaatatgaacccgagatggggaaagtctaccgggctgaccgcaagtcagtgcaaaggatc
aaggctcgggacattgtccccggggacatcgtggaggtggccgtgggggacaaagtcccc
gcagatatccgcatcctaaccatcaaatccaccacgctccgggttgaccagtccatcctg
acaggcgagtccatatctgtcatcaagcacacagaccctgttcctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggtaccaacattgccgctggcaaggccttg
ggcatcgtggccaccactggtgtgagcactgagattgggaagatccgtgaccaaatggcc
gccacagaacaggacaaaacccccctgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgcgtggccgtctggctcatcaacattggccacttcaat
gatcctgtccatgggggctcctggttccggggggccatctactactttaagatcgccgtg
gccctggctgtggccgcaatcccagaaggccttcctgcagtcatcaccacctgcctagcc
ctgggcacccggcggatggcaaagaaaaatgccatcgtgaggagcttgccctccgtagag
actctgggctgcacctctgtcatctgttctgacaagacgggcaccctcaccaccaaccag
atgtctgtgtgcaagatgtttatcatcgacaaggtggacggaaacatctgtgtcctcaac
gagttctccatcactggttccacttacgctccagaaggagaggtcttgaagaatgataag
ccagtccgctcagggcagtacgatgggctggtggagctggccaccatctgtgccctctgc
aatgactcttccttggacttcaatgagaccaaaggtgtttatgaaaaagtgggcgaggcc
accgagaccgcgctcaccaccctggtggagaagatgaatgtattcaacacagacgtgaga
aacctctcgaaggtggagagggccaatgcctgcaactcggtgatccgacagctaatgaag
aaggaattcaccctggagttctcccgggacaggaagtccatgtctgtctactgctcccca
gccaaatcccgggctgctgtgggcaacaagatgtttgtcaagggcgcccccgaaggggtc
attgaccgctgtaactacgtgcgagttggcaccacccgggtgcccatgacggggccggtg
aaggacaagatcttgtcggtgatcaaggagtggggcactggccgggacacgctgcgctgc
ctggccctggccacccgggacacccccccgaagcgagaggagatgatcctggaggattct
gccaagttcatggagtatgagacggacctgacattcatcggcgtggtgggcatgctggac
ccaccccgcaaggaggtcacaggctctattcagctgtgccgggacgctggaatccgagtc
atcatgatcaccggggacaacaagggcacagccattgccatctgccggcgaatcggcatc
ttcggggagaacgaggaggtggccgaccgagcctataccggccgggagttcgacgacctg
cccctggctgagcagcgggaggcctgccgtcgagcctgctgcttcgcccgcgtggagcca
tcccataagtcgaagatcgtggagtatctgcagtcctatgatgagatcacggccatgaca
ggtgacggggtcaacgacgcgcccgccctgaagaaggccgagatcggcatcgccatggga
tccggcaccgccgtggccaagacggcctccgagatggtcctggccgacgacaacttctcc
accatcgtggccgcggtggaggagggccgcgccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctgaccgccgcctta
gggctgcccgaggccctgatccctgtgcagctgctgtgggtgaacttggtgaccgacggg
ctcccggccacggcgctgggcttcaacccaccagacctggacatcatggaccggcccccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcgattggg
ggctacgtgggtgcggccaccgtgggagcagcagcctggtggttcctgtacgcagatgac
gggcctcatgtcacctacagccagctgactcatttcatgcagtgcaacgaggaaaaccct
gactttgagggcctggactgcgaggtctttgaggcctccgagcccatgaccatggccttg
tccgtgctggtgaccatcgagatgtgcaacgccctcaacagcctgtctgagaaccagtcc
ctcctgcggatgcccccctgggtgaacatctggctgctgggctccatctgcctctccatg
tccctccactttctcatcctctacgtcgaccctctgccgatgatcttcaagctccaggcc
ctggacctcacccactggctcatggtcctcaagatctcctttccagtcattgtgctcgat
gagctcctcaagttcgttgctcggaactacctggaggatccagaagatgaaaggaggaag
taa
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