KEGG   Mirounga leonina (Southern elephant seal): 118001265
Entry
118001265         CDS       T07472                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01522  Endocrine resistance
mlx04010  MAPK signaling pathway
mlx04015  Rap1 signaling pathway
mlx04068  FoxO signaling pathway
mlx04071  Sphingolipid signaling pathway
mlx04114  Oocyte meiosis
mlx04148  Efferocytosis
mlx04218  Cellular senescence
mlx04261  Adrenergic signaling in cardiomyocytes
mlx04370  VEGF signaling pathway
mlx04380  Osteoclast differentiation
mlx04550  Signaling pathways regulating pluripotency of stem cells
mlx04611  Platelet activation
mlx04613  Neutrophil extracellular trap formation
mlx04620  Toll-like receptor signaling pathway
mlx04621  NOD-like receptor signaling pathway
mlx04622  RIG-I-like receptor signaling pathway
mlx04625  C-type lectin receptor signaling pathway
mlx04657  IL-17 signaling pathway
mlx04658  Th1 and Th2 cell differentiation
mlx04659  Th17 cell differentiation
mlx04660  T cell receptor signaling pathway
mlx04664  Fc epsilon RI signaling pathway
mlx04668  TNF signaling pathway
mlx04670  Leukocyte transendothelial migration
mlx04714  Thermogenesis
mlx04722  Neurotrophin signaling pathway
mlx04723  Retrograde endocannabinoid signaling
mlx04728  Dopaminergic synapse
mlx04750  Inflammatory mediator regulation of TRP channels
mlx04912  GnRH signaling pathway
mlx04914  Progesterone-mediated oocyte maturation
mlx04917  Prolactin signaling pathway
mlx04926  Relaxin signaling pathway
mlx04932  Non-alcoholic fatty liver disease
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx04935  Growth hormone synthesis, secretion and action
mlx04936  Alcoholic liver disease
mlx05014  Amyotrophic lateral sclerosis
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05132  Salmonella infection
mlx05133  Pertussis
mlx05135  Yersinia infection
mlx05140  Leishmaniasis
mlx05142  Chagas disease
mlx05145  Toxoplasmosis
mlx05152  Tuberculosis
mlx05161  Hepatitis B
mlx05163  Human cytomegalovirus infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05171  Coronavirus disease - COVID-19
mlx05205  Proteoglycans in cancer
mlx05208  Chemical carcinogenesis - reactive oxygen species
mlx05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlx05415  Diabetic cardiomyopathy
mlx05417  Lipid and atherosclerosis
mlx05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118001265 (MAPK14)
   04015 Rap1 signaling pathway
    118001265 (MAPK14)
   04370 VEGF signaling pathway
    118001265 (MAPK14)
   04668 TNF signaling pathway
    118001265 (MAPK14)
   04068 FoxO signaling pathway
    118001265 (MAPK14)
   04071 Sphingolipid signaling pathway
    118001265 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    118001265 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118001265 (MAPK14)
   04218 Cellular senescence
    118001265 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    118001265 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118001265 (MAPK14)
   04613 Neutrophil extracellular trap formation
    118001265 (MAPK14)
   04620 Toll-like receptor signaling pathway
    118001265 (MAPK14)
   04621 NOD-like receptor signaling pathway
    118001265 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    118001265 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    118001265 (MAPK14)
   04660 T cell receptor signaling pathway
    118001265 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    118001265 (MAPK14)
   04659 Th17 cell differentiation
    118001265 (MAPK14)
   04657 IL-17 signaling pathway
    118001265 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    118001265 (MAPK14)
   04670 Leukocyte transendothelial migration
    118001265 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    118001265 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    118001265 (MAPK14)
   04917 Prolactin signaling pathway
    118001265 (MAPK14)
   04926 Relaxin signaling pathway
    118001265 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    118001265 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118001265 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    118001265 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    118001265 (MAPK14)
   04722 Neurotrophin signaling pathway
    118001265 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118001265 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118001265 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    118001265 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    118001265 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    118001265 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118001265 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    118001265 (MAPK14)
   05161 Hepatitis B
    118001265 (MAPK14)
   05171 Coronavirus disease - COVID-19
    118001265 (MAPK14)
   05163 Human cytomegalovirus infection
    118001265 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118001265 (MAPK14)
   05169 Epstein-Barr virus infection
    118001265 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118001265 (MAPK14)
   05135 Yersinia infection
    118001265 (MAPK14)
   05133 Pertussis
    118001265 (MAPK14)
   05152 Tuberculosis
    118001265 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118001265 (MAPK14)
   05140 Leishmaniasis
    118001265 (MAPK14)
   05142 Chagas disease
    118001265 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    118001265 (MAPK14)
   05020 Prion disease
    118001265 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    118001265 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118001265 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    118001265 (MAPK14)
   05415 Diabetic cardiomyopathy
    118001265 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118001265 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    118001265 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    118001265 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118001265 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118001265 (MAPK14)
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118001265 (MAPK14)
Protein kinases [BR:mlx01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118001265 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 118001265
NCBI-ProteinID: XP_034847199
LinkDB
Position
Unknown
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGADLLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccacgttctaccggcaggagctgaacaagacaatctgggaggtg
cccgagcgttaccagaatctgtccccggtgggctccggtgcctatggctccgtgtgtgct
gcttttgacacaaaaaccgggttacgtgtggcagtgaagaagctctccagaccatttcag
tccattattcatgccaaaaggacctacagagaactgcggttacttaaacatatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtcacccatctcatgggagcagatctgaacaacattgtgaaatgtcag
aagcttacggatgaccatgttcagttcctcatctaccagattctccgaggtctcaagtat
atacattcagctgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgtgagctgaagatcttggattttggactggcccgacatacagatgatgaaatgaca
ggctatgtggccaccaggtggtaccgggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcagtgggatgcataatggccgagctgttgactggaaga
acgttgtttcctggtacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgatcttttgaagaaaatctcctcagagtctgcaagaaactacattcag
tctttgacccagatgccgaaaatgaactttgcaaatgtatttattggcgccaatcccttg
gctgtcgacttgctggagaagatgcttgtattggactcagacaagagaattacggcagcc
caagccctcgcacatgcctattttgctcagtaccatgatcctgatgatgaaccagtggct
gatccttacgatcagtcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctacgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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