Mirounga leonina (Southern elephant seal): 118001954
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Entry
118001954 CDS
T07472
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X1
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00230
Purine metabolism
mlx01100
Metabolic pathways
mlx04024
cAMP signaling pathway
mlx05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118001954
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
118001954
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118001954
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
118001954
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
118001954
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Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
118001954
NCBI-ProteinID:
XP_034848039
LinkDB
All DBs
Position
Unknown
AA seq
784 aa
AA seq
DB search
MRIEERKSSILTGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKPEDESAP
KEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYELSSIIKIATKADGFALYFLGEC
NNSLCVFTPPGIKEGKPRLIPAGPIAQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLE
SGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCMSHQEVATANLAWASVAIHQVQVC
RGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELY
SDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYT
GYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHR
IRHSECIYRVTMEKLSYHSICTAEEWQGLMHFNLPVRLCKEIELFHFDIGPFENMWPGIF
VYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHGLFTD
LERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNI
FSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMM
TACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFY
NAVAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRGEESAVWISSQPGAHGPSEKLPV
KIDD
NT seq
2355 nt
NT seq
+upstream
nt +downstream
nt
atgaggatagaagagaggaaatccagcattttaacaggtttgacagatgaaaaagtgaag
gcatatctttctcttcatccccaggtgttagacgaatttgtatctgaaagtgttagtgca
gagactgtagaaaaatggctgaagaggaaaaacaacaaaccagaagatgaatcggctcct
aaggaagtcagcaggtaccaagacacgaatatgcagggagttgtgtatgaactaaacagc
tacatagaacaacggttggatacaggaggagacaaccagctactgctctatgaattgagt
agcatcattaaaatagccacaaaagctgatggatttgcactgtatttccttggagagtgc
aataatagtctgtgcgtgttcactccacctggaatcaaggaaggaaaaccccggctcatc
cctgctgggcccattgcccagggcaccaccatttctgcctatgtggccaagtccagaaaa
acgttgctagtggaagacatccttggggatgaacgatttccaagaggtactggactggag
tcagggactcgcatccagtctgttctttgtttaccaattgtcactgcaattggtgacttg
attggtatcctcgagctgtatcggcactggggcaaagaagccttctgtatgagtcatcag
gaggttgcaacagcaaatctcgcctgggcttcagtagcaatacatcaggtgcaggtatgc
agaggccttgctaaacagactgaattgaatgacttcctacttgatgtatcaaagacatat
tttgataacatagtcgcaatagactctctacttgaacacataatgatatatgcaaaaaat
ctggtgaatgccgatcgttgtgcacttttccaggtagaccataagaacaaggagttatat
tcagacctttttgatattggagaggaaaaggaaggaaaacctatcttcaagaagaccaaa
gaaataagattttccatcgagaaaggaattgctggtcaggtagcaagaacaggggaagtc
ctgaacattccagatgcctatgcagacccacgctttaacagggaagtggacctgtacaca
ggctacaccacccggaatatcctgtgcatgcccatcgtgagccggggaagcgtgatcggc
gtggtgcagatggtgaacaagataagcggcagtgccttctcgaaaacggacgaaaacaac
ttcaagatgtttgccgtcttctgtgctttagccttacactgtgccaatatgtatcaccga
atccgtcattccgagtgcatttaccgggtgactatggagaagctttcctaccatagcatc
tgtacggcagaggagtggcagggcctcatgcacttcaacctccccgtgcgcctctgcaaa
gaaattgaattattccactttgacattggtccttttgaaaacatgtggcctggaatcttt
gtctacatggtccatcggtcctgtgggacatcctgctttgagcttgaaaagttgtgtcgt
tttattatgtctgtgaagaaaaactatcggcgggttccttatcacaactggaaacacgcc
gtcactgtggctcactgcatgtacgccattctccagaacaaccacgggctcttcaccgac
cttgagcgcaaaggactgctaatcgcgtgtctgtgtcatgacctggaccacaggggtttc
agtaacagctacctgcagaaattcgatcaccctctggcagctctctattccacttctacc
atggagcagcatcacttctcccagacagtgtccatcctccagttggaagggcacaatatc
ttctccaccctgagctccagtgaatatgaacaggtgctcgagatcatccgcaaagctatc
attgccacagaccttgctctgtactttggaaacaggaaacaattggaggagatgtaccag
accggatcgctaaaccttaataatcaatcacatagagatcgtgtcattggtttgatgatg
actgcctgtgatctttgttctgtaacaaagctgtggccggttacaaaattgacagcaaat
gatatatatgcagagttctgggctgagggcgatgagatgaaaaagttgggaatacaacct
attcccatgatggacagagacaagaaggacgaggtcccacaaggccagctggggttctac
aacgctgtggccatcccctgctacaccaccctcacccagatcttcccgcccaccgagcct
ctcctcaaagcgtgcaggaataacctcagccagtgggagaaggtgatccgaggggaggag
agtgcggtgtggatctcatcccagccaggggcccacgggccctcggagaagctgcctgtg
aagatcgatgactga
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