Mirounga leonina (Southern elephant seal): 118002069
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Entry
118002069 CDS
T07472
Symbol
SOS2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01521
EGFR tyrosine kinase inhibitor resistance
mlx01522
Endocrine resistance
mlx04010
MAPK signaling pathway
mlx04012
ErbB signaling pathway
mlx04014
Ras signaling pathway
mlx04062
Chemokine signaling pathway
mlx04068
FoxO signaling pathway
mlx04072
Phospholipase D signaling pathway
mlx04150
mTOR signaling pathway
mlx04151
PI3K-Akt signaling pathway
mlx04510
Focal adhesion
mlx04540
Gap junction
mlx04630
JAK-STAT signaling pathway
mlx04650
Natural killer cell mediated cytotoxicity
mlx04660
T cell receptor signaling pathway
mlx04662
B cell receptor signaling pathway
mlx04664
Fc epsilon RI signaling pathway
mlx04714
Thermogenesis
mlx04722
Neurotrophin signaling pathway
mlx04810
Regulation of actin cytoskeleton
mlx04910
Insulin signaling pathway
mlx04912
GnRH signaling pathway
mlx04915
Estrogen signaling pathway
mlx04917
Prolactin signaling pathway
mlx04926
Relaxin signaling pathway
mlx04935
Growth hormone synthesis, secretion and action
mlx05034
Alcoholism
mlx05160
Hepatitis C
mlx05161
Hepatitis B
mlx05163
Human cytomegalovirus infection
mlx05165
Human papillomavirus infection
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
mlx05206
MicroRNAs in cancer
mlx05207
Chemical carcinogenesis - receptor activation
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05210
Colorectal cancer
mlx05211
Renal cell carcinoma
mlx05213
Endometrial cancer
mlx05214
Glioma
mlx05215
Prostate cancer
mlx05220
Chronic myeloid leukemia
mlx05221
Acute myeloid leukemia
mlx05223
Non-small cell lung cancer
mlx05224
Breast cancer
mlx05225
Hepatocellular carcinoma
mlx05226
Gastric cancer
mlx05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118002069 (SOS2)
04012 ErbB signaling pathway
118002069 (SOS2)
04014 Ras signaling pathway
118002069 (SOS2)
04630 JAK-STAT signaling pathway
118002069 (SOS2)
04068 FoxO signaling pathway
118002069 (SOS2)
04072 Phospholipase D signaling pathway
118002069 (SOS2)
04151 PI3K-Akt signaling pathway
118002069 (SOS2)
04150 mTOR signaling pathway
118002069 (SOS2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118002069 (SOS2)
04540 Gap junction
118002069 (SOS2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118002069 (SOS2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
118002069 (SOS2)
04660 T cell receptor signaling pathway
118002069 (SOS2)
04662 B cell receptor signaling pathway
118002069 (SOS2)
04664 Fc epsilon RI signaling pathway
118002069 (SOS2)
04062 Chemokine signaling pathway
118002069 (SOS2)
09152 Endocrine system
04910 Insulin signaling pathway
118002069 (SOS2)
04912 GnRH signaling pathway
118002069 (SOS2)
04915 Estrogen signaling pathway
118002069 (SOS2)
04917 Prolactin signaling pathway
118002069 (SOS2)
04926 Relaxin signaling pathway
118002069 (SOS2)
04935 Growth hormone synthesis, secretion and action
118002069 (SOS2)
09156 Nervous system
04722 Neurotrophin signaling pathway
118002069 (SOS2)
09159 Environmental adaptation
04714 Thermogenesis
118002069 (SOS2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118002069 (SOS2)
05206 MicroRNAs in cancer
118002069 (SOS2)
05205 Proteoglycans in cancer
118002069 (SOS2)
05207 Chemical carcinogenesis - receptor activation
118002069 (SOS2)
05208 Chemical carcinogenesis - reactive oxygen species
118002069 (SOS2)
05231 Choline metabolism in cancer
118002069 (SOS2)
09162 Cancer: specific types
05210 Colorectal cancer
118002069 (SOS2)
05225 Hepatocellular carcinoma
118002069 (SOS2)
05226 Gastric cancer
118002069 (SOS2)
05214 Glioma
118002069 (SOS2)
05221 Acute myeloid leukemia
118002069 (SOS2)
05220 Chronic myeloid leukemia
118002069 (SOS2)
05211 Renal cell carcinoma
118002069 (SOS2)
05215 Prostate cancer
118002069 (SOS2)
05213 Endometrial cancer
118002069 (SOS2)
05224 Breast cancer
118002069 (SOS2)
05223 Non-small cell lung cancer
118002069 (SOS2)
09172 Infectious disease: viral
05161 Hepatitis B
118002069 (SOS2)
05160 Hepatitis C
118002069 (SOS2)
05163 Human cytomegalovirus infection
118002069 (SOS2)
05165 Human papillomavirus infection
118002069 (SOS2)
09165 Substance dependence
05034 Alcoholism
118002069 (SOS2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118002069 (SOS2)
01522 Endocrine resistance
118002069 (SOS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
PH_19
IQ_SEC7_PH
PH_10
Motif
Other DBs
NCBI-GeneID:
118002069
NCBI-ProteinID:
XP_034848206
LinkDB
All DBs
Position
Unknown
AA seq
1333 aa
AA seq
DB search
MQQAPQPYEFFSEENSPKWRGLLVSALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRKLFKPSDI
DRIFSNISDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPKFNEHFSKLMARPAVALHFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRIGAKHERHIFLFDGLMISCKPNHSQSRLPG
YSSAEYRLKEKFVMRKIQICDKEDTCECKHAFELVSKDENSIIFAARSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVIKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLLIERFEIPEPEPTEADKLA
VEKGEQPISADLKRFRKEYVQPVQLRILNVFRHWVEHHFYDFERDLELLERLESFISSVR
GKAMKKWVESIAKIIRRKKQAQANGISHNITFESPPPPIEWHISRAGQFETFDLMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAILSRIIEILQVFQDLNNFSGVLEIVSAVNSVSVYRLDHTFEALQERKRRILD
EAVELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSASEKEFTDYLFNKSLEIEPRNCK
QPPRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPCKMSFSRIAETDLESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNNSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEQLLIPPPLPPRKKFDHDASNSKGNTKSDDDPPAIPPRQPPPPKVKPRVPAPTGAFDGP
LHSPPPPPPRDPLPDTPPPVPLRPPEHFINCPFNLQPPPLGHLHRDPDWFRDVSTCPNSP
NTPPSTPSPRVPRRCYMLSSSHNNLAHPQAPPVPPRQNSSPHLPKLPPKTYKRELSHPPS
YRLPLLENAETPQ
NT seq
4002 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccgtacgagttcttcagcgaagagaacagtccgaaatggcgg
ggactactggtctcggccctgcggaaggttcaggagcaagtacatcccaatctctccgct
aatgaagagtctctctattatattgaagagctgatttttcagctgcttaataaattatgc
atggctcaaccaaggactgttcaagatgtggaggaacgtgttcaaaagacctttcctcat
ccaattgataaatgggctattgctgatgcacaatctgccatagaaaaacgaaaacgaaga
aatcctctcttactccctgtggacaaaatccatccttcattgaaggaagttttagggtac
aaagtggactatcatgtatccctgtatattgtggctgtactagagtatatctcagctgat
attttgaagttggctggtaattatgtttttaatatccgacattatgaaatatctcagcag
gacattaaagtgtcaatgtgtgcagataaggttttgatggacatgtttgaccaggatgac
ataggtttggtttctctctgtgaagatgaacccagttcttcaggtgaattaaactactat
gaccttgtcagaactgaaattgcagaagaaaggcagtatctacgggaactaaatatgatc
ataaaagtgtttcgagaagcctttctttccgacagaaagctgtttaaaccttctgatatt
gacaggattttcagtaacatttcagatatacatgaattaactgtgaaacttttaggttta
attgaagacacagttgaaatgactgatgaaagcagtcctcatccgttagctggcagctgt
tttgaagatttggcagaagagcaagcatttgatccttatgaaacgttatcacaggacatt
ctttctccaaaatttaatgaacatttcagtaagttgatggccagacctgcggtggctcta
cactttcagtccattgctgatggttttaaagaggcagttcgttatgtccttccacgcctt
atgctggtgcctgtttatcattgttggcactattttgaattattaaagcaattgaaagca
tgtagtgaagagcaggaagacagagaatgtttgaaccaagctattactgctcttatgaat
ctccaaggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcagttaagaagcaagcatctggctattaaaaaaatg
aatgaaattcagaaaaacatagatggatgggaaggcaaagatattggacagtgttgtaat
gaattcataatggaaggtccattgacacgaattggtgctaaacatgaacgacatattttt
ctctttgatggcttaatgatcagctgtaagcccaatcatagtcagtcacgccttccaggt
tatagtagtgcagaatacagattaaaagaaaaatttgtcatgaggaaaatacaaatatgt
gataaagaagatacttgtgagtgcaaacatgcttttgagttggtatccaaagatgaaaat
agcataatatttgctgctaggtctgctgaagagaaaaataattggatggctgcacttatt
tctcttcactatcgtagtacactagatcgaatgctagattcagtgttattgaaagaagaa
aatgagcaaccattgagattaccaagtcctgaagtgtatcgttttgtgataaaagactct
gaggaaaacattgtttttgaagacaacctgcaaagtagaagtggaatccccattattaaa
ggaggaactgtagtgaaattaattgaaaggttaacatatcatatgtatgcagatcccaat
tttgttcgtacttttcttactacataccgttcattttgtaaaccacaggaattgctaagc
ttactgattgaacgatttgaaattccagagccagaacctactgaagcagataaattggcc
gtagagaaaggcgaacagccaatcagtgcagaccttaaaaggtttcgcaaggaatatgtc
caaccagtacaacttaggattttaaatgtgtttcggcactgggttgaacaccatttttat
gactttgaaagagatttggagttgcttgaaagactagaatccttcatttcaagtgtaaga
gggaaagctatgaagaaatgggtagagtcaattgctaagatcatcaggagaaagaaacaa
gctcaggcaaatggaataagccataatattacctttgaaagtccacctccgccaattgaa
tggcatatcagcagagcgggacagtttgaaacatttgatctcatgacacttcatccaata
gaaattgcacgtcagctgacacttttggaatctgatctctacaggaaagtccaaccttct
gaactagtagggagtgtatggaccaaagaagataaagaaataaattctccaaatttatta
aaaatgattcgccataccacaaatctcaccctatggtttgaaaagtgcattgtggaagca
gaaaattttgaggagcgggtggcaatactaagtagaattatagaaattctgcaagttttt
caagatttgaataatttcagtggtgtattggagatagtcagtgcggtaaattcagtgtcg
gtatacagactagaccatacttttgaggcgttgcaggaaagaaaaaggagaattttggat
gaagctgtggaattaagtcaagatcactttaaaaaatacctagtaaaacttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaaaactgaagaa
gggaataatgattttttaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattacgggagaaattcagcagtatcagaatcaaccttactgtttacgg
atagaaccagaaatgaggaggttctttgaaaaccttaaccccatgggaagtgcttctgaa
aaggagtttacagattatttgttcaacaagtcactagaaattgaaccccgaaactgcaaa
cagccacctcgatttcctaggaagtcaactttctctttaaaatctcctggaatacggcct
aatacaggccgacatggctctacctcaggcactttacgaggtcatccaacgccattagaa
agagaaccatgtaaaatgagctttagtcggattgctgaaactgatcttgaatcaactgtg
tcagcaccaacctctccaaatacaccatctactccaccagtatctgcttcttcagacctt
agtgtgtttttagatgtggatctcaacaattcctgtggcagcaatagcatctttgctcca
gtcctcttgccacactcaaagtccttcttcagttcatgtggcagtttacacaaactaagt
gaagagcagctgctgattcctcctccgcttcctcctcgaaagaagtttgatcatgacgct
tcaaattccaagggaaatacgaaatctgatgatgacccccctgctattccaccaagacaa
cctcctcctccaaaggtaaaacccagagttcctgctcctactggtgcatttgatgggcct
ctgcatagtccacctccaccaccgccaagagatcctcttcctgatacccctccaccagtt
cccctccggcctccagaacactttataaactgtccatttaatcttcagccacctccacta
ggacatcttcacagagatccagactggttcagagacgttagtacctgtccaaactcgcca
aatactcctcctagcacaccctctccgagagtaccacgtcgatgctacatgctcagttct
agtcacaacaaccttgctcatcctcaagctccccctgttccaccaaggcagaattcaagc
cctcacctaccaaaactgccaccaaagacttacaaacgggagctttcgcaccctccgtca
tacagactgcctttgctagaaaatgcggaaactcctcaatga
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integrated database retrieval system
