Mirounga leonina (Southern elephant seal): 118002352
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Entry
118002352 CDS
T07472
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X1
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04066
HIF-1 signaling pathway
mlx04137
Mitophagy - animal
mlx04140
Autophagy - animal
mlx04148
Efferocytosis
mlx04659
Th17 cell differentiation
mlx04919
Thyroid hormone signaling pathway
mlx05167
Kaposi sarcoma-associated herpesvirus infection
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05211
Renal cell carcinoma
mlx05230
Central carbon metabolism in cancer
mlx05231
Choline metabolism in cancer
mlx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118002352 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118002352 (HIF1A)
04137 Mitophagy - animal
118002352 (HIF1A)
04148 Efferocytosis
118002352 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
118002352 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118002352 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118002352 (HIF1A)
05205 Proteoglycans in cancer
118002352 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
118002352 (HIF1A)
05230 Central carbon metabolism in cancer
118002352 (HIF1A)
05231 Choline metabolism in cancer
118002352 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118002352 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
118002352 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
118002352 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mlx03000
]
118002352 (HIF1A)
Transcription factors [BR:
mlx03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
118002352 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
118002352
NCBI-ProteinID:
XP_034848632
LinkDB
All DBs
Position
Unknown
AA seq
823 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGLVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTET
DDQQLEEVPLYNDVMLPSSNDKLQNINLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSTSPQSASTVTVFQ
PTQIQEPPVTTTSTTATTDELKTVTKDGTEDIKILIASPSPTHVPKVTTSATASPYSDTG
SRTASPNRAGKGVIEQTEKSHPRSPNVLSVTLSQRTTIPEEELNPKILALQNAQRKRKIE
QDGSLFQAVGIGTLLQQPDDRATTTSLSWKRVKGCKSSEHNGMEQKTIILIPSDLACRLL
GQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2472 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaagataagttctgaacgtagaaaagaa
aagtctagagatgcagctagatctcggagaagtaaagagtccgaagttttttatgagctt
gctcatcagttgccacttccccataatgtgagctcgcatcttgataaggcttctgttatg
aggcttaccatcagctatttgcgtgtaaggaaacttctggatgctggtgatttggatatt
gaagatgaaatgaaggcacagatgaattgcttttatttgaaagccctagatggttttgtt
atggttctcacagatgatggtgacatgatttatatttctgataatgtgaataaatacatg
ggattgactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggccttgtgaaaaagggtaaagag
cagaatacacagcgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga
actatgaacataaagtcagcaacatggaaagtacttcactgcacaggccatattcatgtc
tacgataccaatagtaaccaatctcagtgtgggtataagaaaccacccatgacgtgcttg
gtgctaatttgtgaacccattcctcatccatcaaatattgaaattcctttagatagcaag
acttttctcagtcgtcacagtctggatatgaaattttcttattgtgatgaaagaattact
gaattgatgggatatgagccagaagaacttttgggccgctcaatttatgaatattatcat
gctttggactctgaccatctgaccaaaactcatcatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatataacactaagaactctcaaccacagtgcattgtatgtgtaaattat
gttgtgagtggtattattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaaccagttgaatcttcagatatgaaaatgactcagctattcaccaaagttgaatca
gaagatacaagtagtctctttgataaacttaagaaggaacccgatgctttaactttgctg
gccccagctgctggagacacaatcatatctctagatttcggcagcaatgacacagaaact
gatgaccaacaacttgaggaagttccgttgtataatgacgtaatgctcccctcatccaac
gacaaattacagaatataaatttggcaatgtctcccttacctgcttctgaaactccaaag
ccacttcgaagtagtgctgaccctgcactcaatcaagaagttgcattaaaattagagcca
aatccagagtccctggaactttcttttactatgccccagattcaagatcagccagctagt
ccttctgatggaagcactagacaaagttcacctgagcctaacagtcccagtgaatattgt
tttgatgtggatagtgatatggtcaatgaatttaagctggaattagtagagaaacttttt
gctgaagacacagaagcaaagaatccattttccacccaggacactgatttagacttggag
atgttagctccttatatcccaatggatgatgacttccagttacgttccttcgatcagttg
tcaccactggaaagcagttctacaagccctcagagtgcgagcacagttacagtattccag
cctactcaaattcaagagcctcctgtgaccactaccagtaccactgctaccactgatgaa
ttaaaaacagtgacaaaagatggtacagaagatattaaaatactgattgcatctccatct
cctacccatgtacctaaagtaactactagtgccacggcatcaccatacagtgatactgga
agtcggacagcctcaccaaacagagcaggaaaaggagtcatagaacagacagaaaaatct
catccaagaagccctaacgtgttatctgtcactttgagtcaaagaactaccattcctgag
gaagaactaaatccaaagatactagctttgcagaatgctcagagaaagcgaaaaatagaa
caggacggttcactttttcaagcagtaggaattggaacattattacagcagccagacgat
cgtgcaactactacatcactttcttggaaacgcgtaaaaggatgcaaatctagtgaacac
aatggaatggagcaaaagacaattattttaataccctctgatttagcatgtagactgctg
gggcaatcaatggatgagagtggattaccacaactgaccagttatgattgtgaagttaat
gctcctatacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggat
caagttaactga
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