Mirounga leonina (Southern elephant seal): 118002956
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Entry
118002956 CDS
T07472
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118002956 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlx03032
]
118002956 (TOP2B)
03036 Chromosome and associated proteins [BR:
mlx03036
]
118002956 (TOP2B)
Enzymes [BR:
mlx01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
118002956 (TOP2B)
DNA replication proteins [BR:
mlx03032
]
Eukaryotic type
DNA Topoisomerases
118002956 (TOP2B)
Chromosome and associated proteins [BR:
mlx03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
118002956 (TOP2B)
Centrosome formation proteins
Centriole proteins
118002956 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
118002956
NCBI-ProteinID:
XP_034849483
LinkDB
All DBs
Position
Unknown
AA seq
1621 aa
AA seq
DB search
MAKAGGGGGAGAGGNGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQLE
HILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKN
MTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGG
RNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQP
DLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDE
TGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVV
KKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKA
ASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTE
GDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKS
YDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKAS
KNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYA
GPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINK
ELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGE
QALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLSRLLFPAV
DDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLD
GLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLE
PMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMV
LFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQG
KITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPD
FNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFADELDKVEAQ
EREDVLAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADVSKKLLKKKK
GDLDTTTVKVEFDEEFSGTPVEGTGEEALVPSAPVNKGPKPKREKKEPGTRVRKTPTSSG
KSSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDA
DDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSSHDKKGQD
FGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDT
TAKPKRAPKQKKVEPINSDSDSEFGIPKKTTPPKGKGRGAKKRKASGSENEGDYNPGRKT
SKTTSKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMF
N
NT seq
4866 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcggcgcgggagccggcggcaacggggcactgacctgg
gtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcaaacaaa
aatgattcttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaa
catattctccttcgtcctgatacatatattgggtcagtggaaccattgacacagctaatg
tgggtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggttta
tacaagatctttgatgaaattttggttaatgcagctgacaataaacagagggataagaat
atgacctgtattaaagtttctattgatcctgaatcaaatattataagcatttggaataat
gggaaaggcattccagtagtagaacacaaagtagagaaagtttatgttccagcgttaatt
tttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagtaacaggtggt
cgcaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaaact
gcttgcaaagaatacaaacatagttttaagcagacatggatgaataacatgatgaagact
tctgaagccaaaattaagcattttgatggtgaagattacacatgcataacattccaacca
gatctgtctaaatttaagatggaaaagcttgacaaggatattgtggccctcatgactaga
agagcttatgatttggctggctcatgcaagggggtcaaggtcatgtttaatggaaagaaa
ttgcctgtaaatggatttcgcagttatgtagatctttatgtgaaagacaagttggatgaa
actggagtggcgctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctc
acactgagtgaaaagggattccagcaaatcagctttgtaaatagtattgcaacaacaaaa
ggtggacgtcatgtggattatgtagtagatcaagttgttggtaaactgattgaagtagtt
aagaaaaagaacaaagctggtgtatcagtaaaaccatttcaagtaaaaaaccatatatgg
gtttttattaattgccttattgaaaatccaacttttgattctcagactaaggaaaacatg
actctgcaacccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagca
gcttctaactgtggcattgtagaaagtattctgaattgggtgaaatttaaagcccagact
cagctgaacaagaagtgttcatcagtaaagtatagtaaaatcaaaggtattcccaaactg
gatgatgctaatgatgctggtggcaaacattccctggagtgtacactgatattaacagag
ggagactctgccaaatcgttggctgtgtctggattaggtgtgattgggcgagacagatat
ggagtctttccacttaggggaaaaattcttaacgtacgggaagcttctcataaacagatc
atggaaaatgcagaaataaacaatattatcaaaatagttggtctacagtacaagaaaagt
tatgatgatgcagaatctctgaaaaccttacgctatgggaagattatgattatgactgat
caggatcaagatggttctcacattaaaggcctgcttattaatttcatccatcacaattgg
ccatcacttttgaagcatggctttcttgaagagttcattactcctattgtgaaggctagc
aaaaataagcaggaactttccttctatagtattcctgaatttgatgagtggaaaaaacat
atagaaaaccagaaagcctggaaaataaaatactacaaagggctgggtaccagcacagct
aaagaagcaaaggaatattttgctgatatggaaaggcaccgcatcttgtttagatatgct
ggtcctgaagacgatgctgccattaccttggcattcagtaaaaagaagattgatgacaga
aaagaatggttaaccaattttatggaagaccggagacagcgtaggttacatggcttacca
gagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaag
gaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggt
tttaaaccaggacaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaa
gtaaaagttgcccagttggctggatctgttgctgagatgtctgcttatcatcatggagaa
caagcattgatgatgactattgtgaatttggctcagaactttgtgggaagcaacaacatt
aacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgca
agccctcgttatattttcacaatgttaagctctttatcaagactgctttttcctgctgtg
gatgacaacctgctcaaattcctttatgacgataatcaacgcgttgagcctgagtggtat
attcctataattcccatggttttaataaatggtgctgagggcattggtactggatgggct
tgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctagat
ggcttggatcctcatcctatgcttccaaattacaaaaactttaaaggaaccatccaagag
cttggtcaaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagta
gagattacagagcttccagttagaacttggacacaggtatacaaagaacaggttttagaa
cctatgttaaatggaacagataaaacaccggcattaatttctgattataaagaatatcat
actgatacaactgtgaaatttgtggtgaaaatgactgaagagaagctagcacaagcagaa
gctgctggattgcacaaagtttttaaacttcaaactactcttacgtgtaattccatggta
ctctttgatcatatgggatgtctcaagaagtatgaaaccgtgcaagacattttgaaagaa
ttctttgatttacgattaagttattatggtttacgtaaggagtggcttgtaggaatgttg
ggagcagagtctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagga
aaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggt
tatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaa
gaaacacaaaaccagcatgatgatagttcctctgattcaggaactccttcaggccccgat
tttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactg
attaaacagagagatgctaaagggcgagaagtcaatgatcttaaaagaaaatcgccttca
gatctttggaaagaagacttagcagcatttgctgatgaactggataaagtggaagcgcaa
gaacgagaggatgttctggccggaatggctggaaaagcaataaaaggtaaagttggcaaa
cctaaggtgaagaaacttcaattggaagagacaatgccctcaccttatgggagaagaata
gttcctgaaattactgctatgaaggcagatgtcagcaaaaagttgctgaagaagaaaaag
ggtgatcttgataccacaacagtaaaagtagaatttgatgaagaattcagtggaacacca
gtagagggtactggagaagaggcattggtcccgtcagctcctgtaaataaaggtcccaaa
cccaaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggt
aaatccagtgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatccaagtca
gaaagtgacttggaagaaacagaacctgtggttattccaagagattctttgcttaggaga
gcagctgctgaaaggcctaagtacacatttgatttctcagaagaagaggatgatgatgct
gatgatgatgacgacaataatgatttagaggagctgaaagttaaagcatctcccataaca
aatgatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattt
tcaccaggcaaatcaaaagctactccagaaaaatcttcacatgacaaaaaaggtcaagat
tttgggaatctcttctcatttccttcatactctcagaagtcagaagatgattcagctaaa
tttgacagtaatgaagaagattctgcctctgttttttcaccatcatttggtctgaaacaa
acagataaggttccaagtaaaacagtagctgctaaaaagggaaaaccgtcttcagataca
actgctaagcccaagagagctcctaaacagaagaaagtagagcctatcaactctgactca
gattcagaatttggcattccaaagaagactacacccccaaaaggtaaaggccgaggggca
aagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaaca
tccaaaacaacaagcaagaaaccgaagaaaacatcttttgatcaggattcagatgtggac
atcttcccatcagacttcacttctgaaccaccttctctgccacggaccggtagggctagg
aaagaagtaaaatattttgcagagtctgatgaagaagaagatgttgattttgcaatgttt
aattaa
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integrated database retrieval system
