Mirounga leonina (Southern elephant seal): 118003270
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Entry
118003270 CDS
T07472
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00564
Glycerophospholipid metabolism
mlx00565
Ether lipid metabolism
mlx00590
Arachidonic acid metabolism
mlx00591
Linoleic acid metabolism
mlx00592
alpha-Linolenic acid metabolism
mlx01100
Metabolic pathways
mlx04010
MAPK signaling pathway
mlx04014
Ras signaling pathway
mlx04072
Phospholipase D signaling pathway
mlx04217
Necroptosis
mlx04270
Vascular smooth muscle contraction
mlx04370
VEGF signaling pathway
mlx04611
Platelet activation
mlx04664
Fc epsilon RI signaling pathway
mlx04666
Fc gamma R-mediated phagocytosis
mlx04724
Glutamatergic synapse
mlx04726
Serotonergic synapse
mlx04730
Long-term depression
mlx04750
Inflammatory mediator regulation of TRP channels
mlx04912
GnRH signaling pathway
mlx04913
Ovarian steroidogenesis
mlx04921
Oxytocin signaling pathway
mlx05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
118003270 (PLA2G4E)
00565 Ether lipid metabolism
118003270 (PLA2G4E)
00590 Arachidonic acid metabolism
118003270 (PLA2G4E)
00591 Linoleic acid metabolism
118003270 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
118003270 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118003270 (PLA2G4E)
04014 Ras signaling pathway
118003270 (PLA2G4E)
04370 VEGF signaling pathway
118003270 (PLA2G4E)
04072 Phospholipase D signaling pathway
118003270 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118003270 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118003270 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
118003270 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
118003270 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
118003270 (PLA2G4E)
04913 Ovarian steroidogenesis
118003270 (PLA2G4E)
04921 Oxytocin signaling pathway
118003270 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
118003270 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
118003270 (PLA2G4E)
04726 Serotonergic synapse
118003270 (PLA2G4E)
04730 Long-term depression
118003270 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
118003270 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
118003270 (PLA2G4E)
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
118003270 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
ICAT
Motif
Other DBs
NCBI-GeneID:
118003270
NCBI-ProteinID:
XP_034850040
LinkDB
All DBs
Position
Unknown
AA seq
828 aa
AA seq
DB search
MMKAMVGPPMTRKGLTYAGMSQRQQGELSPCHLLTVKVIRMKNVRQADRVSQTDCFVSLW
LPTASREKLKTRTISNCPNPEWNETFSFQIQSQVKNVLELSICDEDTLTPDDHLLTILYD
LTKLCFRKKTHVKFPLNPEGMEELEVEFLLEESPSPPEMLITNGVLVSRQVSCLEVHAEC
QRRKKSRKMKDLLVTVKESFEHTQHVSCCLEPCCANPACFHYPEYFQPCLHVDMPKSPWG
HGLCCCCAQRKTSPVRQPLDCLPDGQTVTLPVGENCELHMKSTPCPPTLDVRLGFSLCPA
EQEFLQKRKVVAAKALQQVLQLEEDLSADEVPLIAIMATGGGTRSMTAMYGHLLGLQKLN
ILNCASYITGLSGATWTMATLYRDPNWSSKNLEPAIFEARRHVVKDKMPALFPDQLSKFQ
EELRQRSQEGYKVTFTDFWGLLIEACLGDERDESKLSDQRAALCEGQNPLPIYLTINVKD
DVSNQDFREWCEFSPYEVGLQKYGAFIPTELFGSEFFMGRLMKRIPESRICYMLGLWSSI
FSLNLLDAWNLSQSSEEFFHRWTRERVHDIEDEPLLPEIPKCDANVLDTTVVIPGSWLSN
TFRSILTHRAFVSQFHNFLLGLQLHTDYLQNSQFSMWRDTVLDGFPNQLTESVSHLCLLD
TAFFINSSYPPLLRPERKVDLIIHLNYCAGSQTKPMKQTCEYCTVQNIPFPKYELQEDEE
NLKECYLLENSQEPDGPIVLFFPLINDSFQKYKAPGVERSPEELEHGHVDIYGPQTPYAT
KELTYTEAAFDKLVKLSEYNILNNKDKLLWALRLAVEKKKHLKSECPS
NT seq
2487 nt
NT seq
+upstream
nt +downstream
nt
atgatgaaggcgatggttggtcctcctatgactaggaaaggcttaacctatgcagggatg
tcacaaaggcaacagggcgagctgtctccatgccacctactgaccgtgaaggtcatccgg
atgaaaaacgtccgacaggctgatagggtgagccagacagactgctttgtgagcctctgg
ctgcccaccgcttctcgtgagaagctgaagactaggactatctccaactgcccgaaccca
gagtggaatgaaaccttcagcttccagatccagagccaagtgaagaacgtgctagagctg
agcatctgtgatgaagatacactgacaccagatgaccatctcttgacaatcctctatgac
ctcaccaaactctgcttccgaaagaaaacccatgtgaagttcccactcaacccggagggc
atggaagagctggaggtagagttcctgctggaggagagtccctctccacccgagatgctc
atcaccaatggcgtgctcgtgtctcggcaagtctcctgcctggaggttcatgcagaatgc
cagaggcggaagaagagcaggaaaatgaaggacctcctggtgacagtgaaggagtccttc
gagcacacccaacacgtttcatgctgcctggagccctgctgcgcaaacccagcctgcttc
cactaccccgagtacttccaaccctgcctgcacgtggacatgcccaagagcccgtggggc
cacgggctttgctgttgctgtgcacagaggaagaccagccctgtccgccagccccttgac
tgcctccccgatggccagacggtgaccctgcccgtgggtgagaactgtgaattacatatg
aagtctacaccctgccctccgacgctggatgtgcggctgggcttcagcctgtgccccgcc
gagcaggagttcctgcagaagcggaaggtggtggcggcaaaggccctgcaacaggtgttg
cagctggaggaggacctgtctgcggacgaggtaccactgatagccatcatggccaccggg
ggtggaacaagatccatgaccgccatgtatggccacctgctggggctgcagaagctgaac
atcctgaactgtgccagctacatcactggcctgtctggggccacctggaccatggctacc
ttgtaccgtgaccctaactggtcctccaaaaacctagagcctgccatatttgaggcacgg
aggcacgtggtcaaagacaagatgcctgccctgttcccagaccagctctccaaattccag
gaggagcttcggcagcgcagtcaggaaggctacaaggtcacctttacagatttctggggc
ctgctgattgaggcctgtctgggggatgagagagatgaatccaaactgtcagatcagcgt
gctgctctgtgtgagggccagaaccccctgcccatctacctcaccatcaatgtcaaggat
gatgtaagcaaccaggatttcagagagtggtgtgagttctccccctacgaggtgggcctg
cagaagtacggggccttcatccccaccgagctcttcggctccgagttcttcatggggcgg
ctgatgaagaggatcccagagtcacggatatgctacatgctaggcttgtggagcagcatc
ttctccctaaacttgcttgatgcctggaatctgtcccaaagctcggaggagtttttccac
agatggaccagggagagagtgcacgacatcgaagatgagccactcctgcccgaaatcccc
aaatgtgatgccaacgtcttggacactacagtggtgatcccagggtcgtggctctccaat
actttccgcagcatcctcacccaccgggcctttgtgtctcagttccacaacttcctgttg
ggcctgcagttgcacaccgactacctccagaacagccagttctccatgtggagagacacg
gtgctagatggtttcccaaaccagctgacagagtctgtgagccacctgtgcctgttggac
accgcattcttcatcaactccagctaccctcccctccttaggcccgagagaaaagtcgac
ctcatcatccacctcaattactgtgctgggtcccagacaaagcccatgaaacaaacctgt
gagtactgcaccgtgcagaacatccccttccccaaatacgagctgcaagaggacgaggaa
aacctcaaggagtgctacttgctggagaactcccaggagcctgatggccccatcgtcctt
ttcttcccactcatcaacgactccttccagaaatacaaggccccaggtgtggagcgaagc
cccgaggagctggaacacggccacgtggacatttatggcccccaaactccatacgctacc
aaggagctgacatacacagaggccgcctttgacaagctggtgaagctctctgagtacaac
atcctgaataacaaggacaagctcctttgggccttgagactggcggtggagaagaagaaa
cacctgaagagcgagtgtccctcctaa
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