Mirounga leonina (Southern elephant seal): 118004181
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Entry
118004181 CDS
T07472
Symbol
PDE3B
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase B isoform X1
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00230
Purine metabolism
mlx01100
Metabolic pathways
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04371
Apelin signaling pathway
mlx04910
Insulin signaling pathway
mlx04914
Progesterone-mediated oocyte maturation
mlx04922
Glucagon signaling pathway
mlx04923
Regulation of lipolysis in adipocytes
mlx04924
Renin secretion
mlx05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118004181 (PDE3B)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
118004181 (PDE3B)
04024 cAMP signaling pathway
118004181 (PDE3B)
04022 cGMP-PKG signaling pathway
118004181 (PDE3B)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118004181 (PDE3B)
04922 Glucagon signaling pathway
118004181 (PDE3B)
04923 Regulation of lipolysis in adipocytes
118004181 (PDE3B)
04914 Progesterone-mediated oocyte maturation
118004181 (PDE3B)
04924 Renin secretion
118004181 (PDE3B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
118004181 (PDE3B)
Enzymes [BR:
mlx01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
118004181 (PDE3B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
DUF1129
Motif
Other DBs
NCBI-GeneID:
118004181
NCBI-ProteinID:
XP_034851286
LinkDB
All DBs
Position
Unknown
AA seq
1104 aa
AA seq
DB search
MRCPQPPDGAASPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELLLPPPASPSAR
ARLSLGALAAFVLALLLGSGPGSWAAGAARLRTLLSVCSHSLSPLFSIACAFFFLTCFLT
RSKRGPGPGRSGGGSWWLLALPACCYLGDFLGWQAWAWAWGSGDAGASAAAPHTPPAVAG
RLFLVLSCVGLLTLAHPARLRHRILVLLFSSLVWWVSFTGLGSLPAALRPLLSCLVGDAG
CLLALGLDHFFQIREAPHHPRLASASEDKVPVIRPRRRSSCVSFGETSAGYSGSCKMFRR
PSLPCISREQMILWDWDLKQWYKPHYQNSGGGSGVDLSVLNEARNMVSDLLIDPTLPPQV
ISSLRSISSLMGAFSGSCRPKLNPLTPFPGFYPCSEIEDPTEKGDRKLHKGLNSRSSLPT
PQLRRSSATSGLPPVEQSSRWERNNGKRPHQDFGISSQGSYLNGPFSSSLLTIAKQRSSS
VSLTHHVGLRRAGAFPSLSPVNSPSHGPVSPGSLTSRSHIEFPDTANFLTKPSVILHRSL
GSAPNSPDTYQQLRNSDSSLCNSCGHQILKYVSTFESESGADCHGGKSGDEDSTIPSKQS
FNCTEAQEVETENRDYRKLFLEGDNHLTEEAQNEQQPNIEQEASLDLILIEDYDSLIEKM
SNWNFQIFEVVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTLQFMNYFRALENGYRDI
PYHNRIHATDVLHAVWYLTTRPVPGLQQIHNDHAAGNETDSGGRMNPGQLAYISSRSCSI
PDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHH
AASAWNLYLSRPEYNFLLNLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNS
DGIEWSNERDRLLVCQVCIKLADINGPAKARDLHLKWTEGIVDEFYEQGDEEANLGLPIS
PFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWVEAEEDEDTESCYDEEDGEEL
DTDDEELEDSLNPKPRRRKGRRRIFCQLMHHLTENHKIWKEMIEEEEKCKADGNKLQVET
PSLPQADDIQVIEEADEEEERQFE
NT seq
3315 nt
NT seq
+upstream
nt +downstream
nt
atgcggtgcccgcagccgccggacggggccgcctcgccccccgagagtctgaggaacggc
tacgtgaagagctgcgtgagccccctgcggcaggaccctccgcgcggcttcttcttccac
ctctgccgcttctgcaacgtggagctgctgctgccgccaccggcctccccctccgcccgg
gcgcgcctctcgctgggcgccctggccgcctttgtcctcgccctgctgctcggctcgggg
cccgggagctgggctgccggggccgcccggctgcggaccctgctgagcgtgtgctctcac
agcctcagccccctgttcagcatcgcctgtgcctttttcttcctcacctgcttcttgacc
cggagcaagcggggccccgggccgggccggagcggcggcggctcctggtggctgctggcg
ctgcccgcctgctgttacctgggggacttcttggggtggcaggcgtgggcgtgggcttgg
gggtccggagacgcgggggcctccgccgcggccccgcacacgcccccggcggtggcgggc
aggttgttcttggtgctgagctgcgtgggcttgctgacgctcgcgcacccggcgaggctc
cggcaccgcatcctggtgctgctcttctccagcttggtctggtgggtctccttcaccggc
ctcgggtctctgcccgctgccctcaggccgctgctctcctgcctggtcggggacgccggc
tgcctgctagccctgggcttggatcacttctttcagatcagggaagcccctcaccatcct
cgcttggccagtgcctccgaggacaaagtgcctgtgatcagaccccgcaggaggtccagc
tgcgtgtcgttcggagaaacttcggccggttactccggcagttgcaagatgttcaggaga
ccttcgttgccttgcatttcccgagaacagatgattctttgggattgggacttaaagcaa
tggtataaacctcattatcagaattctggaggtggaagtggagtggatctttcagtgcta
aatgaggctcgcaatatggtgtcagatctgctgatcgatccaacccttcccccacaagtt
atttcctccctgcggagtatcagtagcttgatgggtgctttctcaggttcctgtaggcca
aagcttaatcctctcacgccatttcctggattttacccctgctcagaaatagaggaccca
actgagaaaggagatcgaaaacttcacaagggactaaatagtaggagtagtttaccaact
ccacagctgaggaggagttccgcaacctcaggtctgcctcccgttgaacagtcttcaagg
tgggaacgcaataatggcaagaggccacaccaagactttggcatttcaagtcaaggatcc
tatctaaatgggccttttagttcaagtctactgacaatcgcgaagcaaaggtcatcttct
gtatccctaactcaccatgtaggtctgagaagagctggtgctttccccagcctgagtcct
gtgaattctcccagccatggaccagtgtctcctggctctctaaccagtcgatcacacata
gaatttcctgacactgccaattttcttactaagccaagtgttattttacacagatctctg
ggcagtgcacccaattcaccagatacttatcagcaactcagaaattctgatagcagtttg
tgtaacagctgtggacatcaaatattgaaatacgtgtcaacattcgaatctgagtctggt
gcagactgccatggtggaaagtcaggtgacgaagatagcaccattccctcaaaacaatca
ttcaactgcacagaagcgcaggaagtggaaacagagaacagagactacagaaaattattt
ttggaaggtgataatcacctaacagaagaggcacagaatgaacagcaaccaaatattgaa
caggaagcatcactggatctgattttaatagaagattatgattccttaatagaaaagatg
agcaactggaattttcaaatatttgaagttgtagaaaaaatgggagagaaatcaggaagg
atccttagtcaggttatgtataccttatttcaagacactggcttattggaaatatttaaa
atccccactctacagttcatgaactattttcgtgcattggagaatggctaccgagacatt
ccttatcataatcgcatacacgccacagatgtcctgcatgcagtttggtatctgacaacg
cggccagttcctggtttacagcagatccacaatgaccacgcagcaggaaatgaaacagat
tctggtggcagaatgaaccctgggcagttggcttacatttcttcgaggagctgctctatt
ccagacgagagctatggttgcctttcttcaaacattcctgcgctggaattgatggctctc
tatgtggcagccgccatgcatgattacgatcacccagggcggacaaatgcatttctagtg
gctacaaatgcccctcaggcagttttgtacaacgacagatctgttctagaaaatcatcat
gctgcatcagcttggaatctgtatctctctcgcccagaatacaacttccttcttaatctt
gatcatgtggaattcaagcgctttcgttttttggtcattgaagcaatccttgccacagat
cttaaaaagcattttgatttccttgctgaattcaacgccaaggccaacgatgtaaatagc
gacggcatagagtggagcaatgagcgtgaccgcctcttagtatgccaggtgtgcatcaag
ctggcagacatcaacggcccggcgaaagctcgggacttgcatttgaaatggacagaaggc
attgtcgatgaattttatgagcagggagatgaggaagcaaacctcggtttgcccatcagt
cccttcatggatcgttcttcgcctcagctagcaaaactccaagaatctttcatcacccac
atcgtgggtcctctgtgtaattcctacgacgcggctggcttgctgccaggtcagtgggta
gaagcagaagaggacgaggacaccgagagttgttacgacgaagaagatggtgaagaatta
gatacagatgatgaagaactagaagacagtctaaatcctaaaccacggaggaggaaaggc
agacggcgaatattttgtcagctaatgcaccacctcactgaaaaccacaagatatggaag
gaaatgatagaggaagaagagaaatgtaaagctgatgggaataaactgcaggtggaaact
ccttccttacctcaagcagatgacattcaggtcattgaagaagcagatgaagaggaggag
agacagtttgaataa
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