Mirounga leonina (Southern elephant seal): 118004574
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Entry
118004574 CDS
T07472
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04062
Chemokine signaling pathway
mlx04071
Sphingolipid signaling pathway
mlx04270
Vascular smooth muscle contraction
mlx04350
TGF-beta signaling pathway
mlx04360
Axon guidance
mlx04510
Focal adhesion
mlx04520
Adherens junction
mlx04530
Tight junction
mlx04611
Platelet activation
mlx04670
Leukocyte transendothelial migration
mlx04810
Regulation of actin cytoskeleton
mlx04921
Oxytocin signaling pathway
mlx05135
Yersinia infection
mlx05163
Human cytomegalovirus infection
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
mlx05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
118004574 (ROCK1)
04071 Sphingolipid signaling pathway
118004574 (ROCK1)
04024 cAMP signaling pathway
118004574 (ROCK1)
04022 cGMP-PKG signaling pathway
118004574 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118004574 (ROCK1)
04520 Adherens junction
118004574 (ROCK1)
04530 Tight junction
118004574 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118004574 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118004574 (ROCK1)
04670 Leukocyte transendothelial migration
118004574 (ROCK1)
04062 Chemokine signaling pathway
118004574 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
118004574 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
118004574 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
118004574 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118004574 (ROCK1)
05206 MicroRNAs in cancer
118004574 (ROCK1)
05205 Proteoglycans in cancer
118004574 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
118004574 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
118004574 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118004574 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlx03036
]
118004574 (ROCK1)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
118004574 (ROCK1)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
118004574 (ROCK1)
Chromosome and associated proteins [BR:
mlx03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
118004574 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Cortex-I_coil
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
118004574
NCBI-ProteinID:
XP_034851870
LinkDB
All DBs
Position
Unknown
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDLLN
HSEKEKNNLEIDLNYKLKSLQQHLEQEVNEHKVTKACLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKHMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNREYLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHIVSRLEETNSMLTKDIELLRKENE
ELTDKMRRAEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQTVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccactaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgccttt
ttctgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctataccgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcacagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgtgaatgtgac
tggtggtcagttggggtctttttatatgaaatgcttgtaggtgatacacccttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggaaacactcagagacactgtagcaccagttgtaccggatttaagt
agtgacatcgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcagttaccttttgtaggatttacgtattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataagagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggagaaaatgttgctacagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcaaaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttagaacagaatcagacaca
gccgtaagattaaggaagagtcacacagagatgagtaagtcagttagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtattagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacctgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttaaactataagcttaaatcatta
caacaacatttagaacaagaggtaaatgaacataaagtaaccaaagcttgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagctcgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatcccttcaactggagcaggaatca
aacaagcgactgttgttacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtttagaaaagcacatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctccaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaatatttaaagaaaatacaagag
ctacaaagtgagaaggaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcagttggctcgagggctgctggaagaacagtattttgaattaacccaagaaagc
aagaaagctgcttccagaaatagacaagagattacagataaagatcatattgttagtcgg
cttgaagaaacaaacagcatgttaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaatgaggagggcagaggaagaatataaattgaagaaggaggaggag
atcagtaatcttaaggctgcctttgaaaagaatatcaatacagaaagaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaggaaaaggaaaatcgaaagctgcaactggaa
ctcaaccaagaaagagagaaattcaaccagacggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgaacttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggtaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcacgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagcggagaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcatgtgccaaacctctctggcatgtttttaagccacctcctgccctggaa
tgtcgaagatgccacgtgaagtgccacagagatcacttggataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtaaaaaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacgctttctacaagatctactgcaaatcag
tctttccgaaaagtggtcaaaaatacatctggaaaaactagcagttaa
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integrated database retrieval system
