Mirounga leonina (Southern elephant seal): 118004956
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Entry
118004956 CDS
T07472
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04217
Necroptosis
mlx04380
Osteoclast differentiation
mlx04620
Toll-like receptor signaling pathway
mlx04621
NOD-like receptor signaling pathway
mlx04630
JAK-STAT signaling pathway
mlx04658
Th1 and Th2 cell differentiation
mlx04659
Th17 cell differentiation
mlx05145
Toxoplasmosis
mlx05160
Hepatitis C
mlx05161
Hepatitis B
mlx05162
Measles
mlx05164
Influenza A
mlx05165
Human papillomavirus infection
mlx05167
Kaposi sarcoma-associated herpesvirus infection
mlx05168
Herpes simplex virus 1 infection
mlx05169
Epstein-Barr virus infection
mlx05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
118004956 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
118004956 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
118004956 (TYK2)
04621 NOD-like receptor signaling pathway
118004956 (TYK2)
04658 Th1 and Th2 cell differentiation
118004956 (TYK2)
04659 Th17 cell differentiation
118004956 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
118004956 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
118004956 (TYK2)
05160 Hepatitis C
118004956 (TYK2)
05171 Coronavirus disease - COVID-19
118004956 (TYK2)
05164 Influenza A
118004956 (TYK2)
05162 Measles
118004956 (TYK2)
05168 Herpes simplex virus 1 infection
118004956 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
118004956 (TYK2)
05169 Epstein-Barr virus infection
118004956 (TYK2)
05165 Human papillomavirus infection
118004956 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
118004956 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118004956 (TYK2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118004956 (TYK2)
Protein kinases [BR:
mlx01001
]
Non-receptor tyrosine kinases
JAK family [OT]
118004956 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
Kinase-like
Kdo
FERM_C_FAK1
RA_2
APH
ABC1
RIO1
Motif
Other DBs
NCBI-GeneID:
118004956
NCBI-ProteinID:
XP_034852431
LinkDB
All DBs
Position
Unknown
AA seq
1196 aa
AA seq
DB search
MPLCHWGATTRDSKPDGDGAQPMATKGGLKVLLHWAGPGGGDPWVTFSEATLTAEEVCIH
IAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEISRDMSLTLYFRMRFYFRNWHGTNPQE
PAIYRCGPPGPKSSSEQTEQGMQLLDPASFEYLFEQGKHEFVNDVASLSELSSEEEIHHF
KNESLGMAFLHLCHLALYHGIPLGKVAKKISFKDCIPRSFRLQIQQHNALTQLRLRNIFR
RFVRAFQPGHVSQQVIMVKYLATLELLAPRFGTECLPVCHLELLAQAVGEPYYIQDGGQA
PPEPGPELATGPPTHEVLVTGTGGIQWRPIQAEGPRGDGSSRNPRAGPFGKKTKAPEVGG
QPADRPQEAPWAYFCDFQDITHVVLKECHVSIHCQDNKSLELTLPSRAMALSLVSLVDGY
FRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVLAKLRPEDGLYLIHWSTSRLNRL
ILTVAQREQAPGTQHVHLRKFPIELQAGGFTLEGWDRSFPSVRELRAALQGCSLRAGDDS
FSLHHCCLPRPGEISNLIIMRGPRASTGPPNLSQLSFHRICQDDITQLSHLGQGTRTNVY
EGILRVGGRGPKEGTADGEDPPTPGGDCGQELRVVLKVLDPSHHDIALAFYETASLMSQV
SHVHLAFVHGICVHGSERRQVGSLRSGRAFADIMVTEYVEHGPLDVWLRREKGHVPVAWK
VAVAQQLASALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREE
RVERIPWTAPECLSGGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKEYFYQKQL
RLPQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADVLAVNPDSPTSDPTI
FHKRYLKKIRDLGEGHFGKVCLYCYDPTNDGTGEMVAVKALKADCGPQLRTGWRREIDIL
RTLYHKHIVKYKGCCEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGM
AYLHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHDYYRVREDGDSPVFWYAPE
CLKECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELMGLTQGQMTVLRLTELLERG
ERLPRPERCPCEIYLLMKNCWEADASFRPTFQNLIPILKTVQEKYQGQAASVFSVC
NT seq
3591 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtgccattggggtgccaccaccagggacagcaagcctgatggagatggagct
cagcccatggccaccaagggaggcctgaaggtccttctgcactgggctggccctggcggc
ggggacccctgggtcaccttcagcgaggccacactgactgcagaggaggtctgcatccac
attgcacaaaaagtcggcatcactccgtcctgcctcaatctctttgctctgttcgatgcc
caggctcaggtctggctgcccccaaaccacgtcttggagatctccagagacatgagcctg
acattgtacttccgcatgaggttttatttccggaactggcatggcacgaatcctcaggag
ccggctatataccgctgtgggcccccagggcccaagtcttcctcagaacagacagagcag
gggatgcaactgctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtggcatcactatcggagctctcgagcgaggaggagatccaccatttt
aagaatgagagcctgggcatggccttcctgcatctctgccaccttgctctctaccatggc
atccccctggggaaggtggccaagaagatcagcttcaaggactgcatcccacgttccttc
cggctgcagatccagcagcacaacgcgctcacgcagctgcgcctgcggaacatcttccgc
aggttcgtgcgggccttccagccaggccacgtgtcgcagcaggtcatcatggtcaaatac
ctggccacgctcgagctgctggcgccccgcttcggcaccgagtgcctgcccgtgtgccac
ctggagctgctggcccaggctgtcggggagccctactacatccaggacggcgggcaggct
cccccagagcctgggccggagttggccaccgggcctcccactcatgaggtgctggtgacg
ggcacgggtggcatccagtggcggccgatacaggcagagggtcccagaggcgacggcagc
agcaggaatccccgtgctggcccatttgggaagaaaaccaaggccccggaggtgggcggc
cagcccgcggacaggcctcaggaagcgccctgggcctacttctgtgacttccaggatatc
acgcacgtggtgctgaaggaatgccacgtcagcatccactgtcaggacaacaagagcctg
gagctgaccctgccttcccgggccatggccctgtccttggtgtcgctggtggacggctac
ttccgcctgaccgccgactcgagccactacctgtgccacgaggtggctccaccacggcta
gtgatgagcatccgggacggtatccacggacctctgctggagccgtttgtgctggccaag
ctgcggcctgaggacggcctctacctcatccattggagcaccagccgcctcaaccgcctc
atcctcacggtggcccagcgtgagcaggccccgggcacccagcacgtgcacctgcgtaaa
ttccccattgagctgcaggctgggggcttcacgctggagggttgggaccggtccttcccc
agcgtgcgggagctgcgggctgccctccagggctgctccctgcgggctggtgatgactct
ttctccctgcaccactgctgcctgcctcggccaggagagatctccaacctcatcatcatg
cgggggcctcgggccagcactggtccgcccaacctcagccagctcagcttccaccggatc
tgccaggatgacatcacccagctgtcccacttgggccaaggcacgaggaccaatgtgtat
gagggcatcttacgagtggggggcagaggccccaaggagggcacggccgatggcgaggac
ccccctacacccggtggggactgtgggcaagagctccgagtggtactcaaggtgctggac
cccagtcaccacgacatcgccctggccttctacgagacagccagcctcatgagccaggtc
tcccacgtgcacctggcctttgtacacggcatctgcgtgcacggctctgagaggaggcag
gtgggcagcctccgcagcggccgggcctttgcagacatcatggtaacagagtacgtggag
cacgggcccctggacgtgtggctgcggcgggagaagggccacgtgcctgtggcctggaag
gtggccgtggcccagcagctggccagcgccctcagctacctggaagacaagagcctggtt
catggtaatgtgtgtggccggaacatcctgctggcgaggctgggactggcagagggcacc
agccccttcatcaagctgagcgaccctggtgtgggcctgggtgccctttctagggaggag
cgggtggagcggatcccctggacagcccccgagtgcctatctggcggagccaacagccta
accactgcagccgataaatggggctttggcgcaaccctcctggagatctgctttgacggg
gaggcccctctgcagggccgtggcccttccgagaaagagtacttctaccagaagcagctc
cggcttcctcagccctcctgcccagagctggccacactcaccagccagtgcctgacctat
gaaccagctcagcggccctccttccgcaccatcctgcgtgacctcactcagctgcagccc
caaaatcttgctgacgtcttggctgtgaaccccgactcgcctacgtcagaccccaccatt
ttccacaagcgctatttgaaaaagattcgggatctgggcgagggtcatttcggcaaggtc
tgcctgtattgctacgaccccacgaatgacggcactggcgagatggtggccgtgaaggcc
ctcaaggcggactgcggcccccagctccgcaccggctggaggcgggagatcgacatcctg
cgcacgctctaccacaagcacatcgtcaagtacaagggctgctgcgaggacccaggcgag
aagtcggtgcagctggtcatggagtacgtgcccttgggcagcctgcgggactacctgccc
cggcacagcgtgggcctggcgcagctgcttctcttcgcccagcagatctgtgagggcatg
gcctaccttcacgcacagcactatgtgcaccgagacctggctgcccgcaacgtgctgctg
gacaacgacaggctggtcaaaatcggggactttggcctagccaaggctgtgcctgaaggc
catgactactaccgtgtgcgcgaagatggggacagccccgtattctggtatgccccagag
tgcctgaaggagtgtaagttctactatgcatccgacgtctggtccttcggggtcaccatg
tatgagctgctgacctactgtgactccagccagagccccccatcgaaattcatcgagctc
atgggcctcacccaggggcagatgacggtgctgaggctcactgaactgctggaacgaggg
gagaggctgccccggccagagagatgtccttgtgagatctatctgctcatgaagaactgc
tgggaggcagacgcttcattccgccccaccttccagaacctcatacccattctcaagacc
gtccaggagaaataccaaggccaggccgcctcagtgttcagcgtgtgctga
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integrated database retrieval system
