KEGG   Mirounga leonina (Southern elephant seal): 118005070
Entry
118005070         CDS       T07472                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01522  Endocrine resistance
mlx04010  MAPK signaling pathway
mlx04014  Ras signaling pathway
mlx04020  Calcium signaling pathway
mlx04024  cAMP signaling pathway
mlx04062  Chemokine signaling pathway
mlx04114  Oocyte meiosis
mlx04140  Autophagy - animal
mlx04211  Longevity regulating pathway
mlx04213  Longevity regulating pathway - multiple species
mlx04261  Adrenergic signaling in cardiomyocytes
mlx04270  Vascular smooth muscle contraction
mlx04310  Wnt signaling pathway
mlx04340  Hedgehog signaling pathway
mlx04371  Apelin signaling pathway
mlx04530  Tight junction
mlx04540  Gap junction
mlx04611  Platelet activation
mlx04713  Circadian entrainment
mlx04714  Thermogenesis
mlx04720  Long-term potentiation
mlx04723  Retrograde endocannabinoid signaling
mlx04724  Glutamatergic synapse
mlx04725  Cholinergic synapse
mlx04726  Serotonergic synapse
mlx04727  GABAergic synapse
mlx04728  Dopaminergic synapse
mlx04740  Olfactory transduction
mlx04742  Taste transduction
mlx04750  Inflammatory mediator regulation of TRP channels
mlx04910  Insulin signaling pathway
mlx04911  Insulin secretion
mlx04912  GnRH signaling pathway
mlx04913  Ovarian steroidogenesis
mlx04914  Progesterone-mediated oocyte maturation
mlx04915  Estrogen signaling pathway
mlx04916  Melanogenesis
mlx04918  Thyroid hormone synthesis
mlx04919  Thyroid hormone signaling pathway
mlx04921  Oxytocin signaling pathway
mlx04922  Glucagon signaling pathway
mlx04923  Regulation of lipolysis in adipocytes
mlx04924  Renin secretion
mlx04925  Aldosterone synthesis and secretion
mlx04926  Relaxin signaling pathway
mlx04927  Cortisol synthesis and secretion
mlx04928  Parathyroid hormone synthesis, secretion and action
mlx04934  Cushing syndrome
mlx04935  Growth hormone synthesis, secretion and action
mlx04961  Endocrine and other factor-regulated calcium reabsorption
mlx04962  Vasopressin-regulated water reabsorption
mlx04970  Salivary secretion
mlx04971  Gastric acid secretion
mlx04976  Bile secretion
mlx05012  Parkinson disease
mlx05020  Prion disease
mlx05030  Cocaine addiction
mlx05031  Amphetamine addiction
mlx05032  Morphine addiction
mlx05034  Alcoholism
mlx05146  Amoebiasis
mlx05163  Human cytomegalovirus infection
mlx05165  Human papillomavirus infection
mlx05166  Human T-cell leukemia virus 1 infection
mlx05200  Pathways in cancer
mlx05203  Viral carcinogenesis
mlx05205  Proteoglycans in cancer
mlx05207  Chemical carcinogenesis - receptor activation
mlx05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118005070 (PRKACA)
   04014 Ras signaling pathway
    118005070 (PRKACA)
   04310 Wnt signaling pathway
    118005070 (PRKACA)
   04340 Hedgehog signaling pathway
    118005070 (PRKACA)
   04371 Apelin signaling pathway
    118005070 (PRKACA)
   04020 Calcium signaling pathway
    118005070 (PRKACA)
   04024 cAMP signaling pathway
    118005070 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118005070 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    118005070 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    118005070 (PRKACA)
   04540 Gap junction
    118005070 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    118005070 (PRKACA)
   04062 Chemokine signaling pathway
    118005070 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    118005070 (PRKACA)
   04910 Insulin signaling pathway
    118005070 (PRKACA)
   04922 Glucagon signaling pathway
    118005070 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    118005070 (PRKACA)
   04912 GnRH signaling pathway
    118005070 (PRKACA)
   04913 Ovarian steroidogenesis
    118005070 (PRKACA)
   04915 Estrogen signaling pathway
    118005070 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    118005070 (PRKACA)
   04921 Oxytocin signaling pathway
    118005070 (PRKACA)
   04926 Relaxin signaling pathway
    118005070 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    118005070 (PRKACA)
   04918 Thyroid hormone synthesis
    118005070 (PRKACA)
   04919 Thyroid hormone signaling pathway
    118005070 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    118005070 (PRKACA)
   04916 Melanogenesis
    118005070 (PRKACA)
   04924 Renin secretion
    118005070 (PRKACA)
   04925 Aldosterone synthesis and secretion
    118005070 (PRKACA)
   04927 Cortisol synthesis and secretion
    118005070 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    118005070 (PRKACA)
   04270 Vascular smooth muscle contraction
    118005070 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    118005070 (PRKACA)
   04971 Gastric acid secretion
    118005070 (PRKACA)
   04976 Bile secretion
    118005070 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    118005070 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    118005070 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    118005070 (PRKACA)
   04727 GABAergic synapse
    118005070 (PRKACA)
   04725 Cholinergic synapse
    118005070 (PRKACA)
   04728 Dopaminergic synapse
    118005070 (PRKACA)
   04726 Serotonergic synapse
    118005070 (PRKACA)
   04720 Long-term potentiation
    118005070 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    118005070 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    118005070 (PRKACA)
   04742 Taste transduction
    118005070 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    118005070 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    118005070 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    118005070 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    118005070 (PRKACA)
   04714 Thermogenesis
    118005070 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118005070 (PRKACA)
   05205 Proteoglycans in cancer
    118005070 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    118005070 (PRKACA)
   05203 Viral carcinogenesis
    118005070 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118005070 (PRKACA)
   05163 Human cytomegalovirus infection
    118005070 (PRKACA)
   05165 Human papillomavirus infection
    118005070 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    118005070 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    118005070 (PRKACA)
   05020 Prion disease
    118005070 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    118005070 (PRKACA)
   05031 Amphetamine addiction
    118005070 (PRKACA)
   05032 Morphine addiction
    118005070 (PRKACA)
   05034 Alcoholism
    118005070 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    118005070 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    118005070 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118005070 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118005070 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:mlx03019]
    118005070 (PRKACA)
   03036 Chromosome and associated proteins [BR:mlx03036]
    118005070 (PRKACA)
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     118005070 (PRKACA)
Protein kinases [BR:mlx01001]
 Serine/threonine kinases: AGC group
  PKA family
   118005070 (PRKACA)
Messenger RNA biogenesis [BR:mlx03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     118005070 (PRKACA)
Chromosome and associated proteins [BR:mlx03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    118005070 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 118005070
NCBI-ProteinID: XP_034852671
LinkDB
Position
Unknown
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgcagccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttcttaaaaaatgggaaaatcctgctcagaatacagcccat
ttggatcagtttgaacggatcaagaccctcggcacgggctcctttgggcgagtgatgctg
gtgaagcacaaggagaccgggaaccactttgccatgaagatcctcgacaaacagaaggtg
gtgaagctgaaacagatcgagcataccctgaacgaaaagcgcatcctgcaagcggtcaac
tttccgttcctcgtcaaactcgagttctccttcaaggacaactcgaatttatacatggtc
atggagtatgtgcctggcggggagatgttctcccacctgcggcggatcggaaggttcagt
gaaccgcatgcccgcttctacgcggcccagatcgtcctgaccttcgagtacctgcactca
cttgacctcatctaccgggacctgaagccggagaacctcctcattgaccagcagggctac
attcaggtgacagacttcggttttgccaagcgtgtaaaaggccgcacctggaccttatgc
gggacccctgagtacctggccccagagatcatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggggttctcatctacgagatggccgctggctacccgcccttcttc
gctgaccagcccatccagatctatgagaagattgtctctgggaaggtgcggttcccatcc
cacttcagctctgacctgaaggatctgctgcggaacctgctgcaggtggacctcaccaaa
cgcttcgggaacctcaagaatggggtcaacgatatcaagaaccacaagtggtttgccaca
actgactggatcgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaattttgacgactatgaggaggaagagatccgagtctccatc
aatgagaagtgtggcaaggagtttactgagttttag

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