Mirounga leonina (Southern elephant seal): 118005686
Help
Entry
118005686 CDS
T07472
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00310
Lysine degradation
mlx01100
Metabolic pathways
mlx05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
118005686 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
118005686 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlx03036
]
118005686 (DOT1L)
Enzymes [BR:
mlx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
118005686 (DOT1L)
Chromosome and associated proteins [BR:
mlx03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
118005686 (DOT1L)
HMT complexes
Dot1-containing complex
118005686 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
118005686
NCBI-ProteinID:
XP_034853609
LinkDB
All DBs
Position
Unknown
AA seq
1658 aa
AA seq
DB search
MVLRTWAGWLGAPRDGGALAGRCVSFPFGSFFLPPRSMASESVHLPICSVSSGACWELPP
EPPSVRLFLLRARHTEALPSAWPARLAVRWWDFRVCLGHSHSLATVGLVRKVPRWQRGRM
SSPMVSVRCRRDPQLGALRGSTVGPRARLSTRAARGTDFHGESLSWFCSDLWEADGTQPC
CCPRGSSLLCQTSFSFHLWCVAVPPRRAVTGVCVSGGRIVSSKPFAPLNFRINSRNLSDI
GTIMRVVELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQR
DNKSTTATPTKLPESKAAVPADTPMDSGAEEEKAGATTIKKPSPSKARKKKLNKKGRKMA
GRKRGRPKKMSTANPERKPKKSQTALDLLHAQAASQTAAPSPQDAYKSPHSPFYQLPPSA
QRQPPDQLLLAPTPPALQKLLESFKIQYLQFLAYTKTAQYKASLQQLLDQEKEKNTRLLG
AAQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLQK
DNRELRSQSLQLLKARCEELKLDWSTLSLENLLKEKQALRTQISEKQRHCLELQISIVEL
EKSQRQQELLQLKSCVPPDDALSAHLRGKGALGRELEADPSRLHLDLDCPKFSLPHLSSA
SPELSMNGHAASYEVCGALSRPSSKQNTPQYLASPLDQEVIPCTPSHSSRPRLEKMSGLA
LPDYTRLSPAKLVLRRHLSQDHVASGKTAASELHPRAEHAKENGLPYQSPGIANGIKLSP
QDPRPSSPMAFQMTGERGGEKGVKERSYASSGEAITSLPVSIPLSTVQPSKLPVSIPLAS
VVLPSRAEKVRSTPSPVPQTRESSSTLEKQMGANAHGAASKGLTPAPAGFYAGSVAVSGA
LAGSPAPLAPGAEPGAFDEVSGSGSLFAGMGPCSTPQHPPLLPQSRGSGAASPAHPLCAS
PRLSSAAQGPLPEASKGDLPSEAGFSDPEGEAKRRVVFTISAGGIAKQSPPGKPSPLPTG
ARGDSGQGHGPDGRKRGRRKRAAAGTPGLSSGVSPKRRALPSVAGLFTQSSGSPLNLSSM
VSNINQPLEITAISSPESLKSSPVPYQDNDQPPILKKEKPLSQTNGAHYSPLTSDEEQGS
EDEPGSARIERKIATISLESKSPPKTLESGGGLAGRKPTPASEPTNSSKWKSTFSPISDL
GLAKCADSPLQAGSALSQNSLFAFRPPLEEPGLAEAKLAAHPRKSFSSALSGAGGLSPSS
NPPNGFTFSGGLAADLSLHSFSDGASLSHKVPEAASLGTPLSFPAPRGKEGSAAESGAFV
NKRQLEGLAGPKGREAGELGLPACGPPDKPLLVHSKPGKGRDREPDLKNGHNLFISAATV
PPGGLLSGPGLATAASSAVSAAPSAQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSL
FSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGVFNHAVPSASAHPFGASFGR
GAACRSATLSLSPLQAVAGAPASSFQAPPPPPPGQPALPAPPPPNAALPPAPALLPANSE
PMLLQNLASLPANQAFLPTSSAASLQPANASLSIKLASLPHKAPRPSFTVHHQPLPGLAL
AQAAPVIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
4977 nt
NT seq
+upstream
nt +downstream
nt
atggttcttaggacgtgggctgggtggctgggtgctcctcgggatgggggcgccctggcc
ggcaggtgtgtttcttttccatttggttctttcttcctcccaccgagaagtatggcttct
gagagcgtgcacctacccatctgcagtgtgtcctccggcgcgtgctgggagctccctcct
gagcctccctctgtgcgccttttcctccttagagctcggcacacggaagcgctgccgtca
gcgtggccggcccgcctggcagtccggtggtgggacttcagggtttgccttggccactca
cactcgcttgcaactgtgggactcgtccgcaaagtgccgagatggcagagggggcgcatg
tcctcgccgatggtgtccgtccggtgccggcgtgacccccagctgggagctctgcggggc
agcactgtggggcccagagcacgtttgtccacgagggccgctcgtgggacggacttccat
ggggaaagcctctcctggttttgctctgacttgtgggaagcggatgggactcagccatgc
tgctgtccccgtggcagctccctcctctgccagacgtcgttttccttccatttgtggtgt
gtagctgtccccccacgaagggcagtaactggtgtttgtgtttcaggtggcagaattgtg
tcctcgaagccctttgcgcctctgaacttcagaataaacagcagaaacttgagtgacatc
gggaccatcatgcgcgtggtggagctctcgcccctgaaaggctcggtgtcctggacgggg
aagccagtctcctactacctgcacaccatcgaccgcaccatacttgaaaactatttttct
agtctgaaaaatccaaaactcagggaggagcaggaagcggcccggcgccggcagcagcga
gacaacaagagcaccacggccactcccaccaagctgcccgagagcaaggccgccgtgccc
gcggacaccccgatggattccggggccgaggaagaaaaagctggggcgaccaccatcaaa
aagccgtcaccctccaaagcccggaagaaaaagctgaacaagaaggggcggaagatggcc
ggccggaagcgcgggcgtcccaagaagatgagcaccgcgaacccggagcgtaagcccaag
aagagccaaactgcactggacctcctgcatgcccaggccgcgtcgcagacggcagcgccc
tcgccgcaggatgcgtacaagtcacctcacagcccgttttatcagctacctcccagtgcg
cagcggcagccccccgaccagctgctgctggcacccaccccgcccgcactgcagaagctg
ctagaatccttcaagattcagtacttgcagttcttggcgtacaccaagaccgcccagtac
aaggccagcctgcagcagctgctggaccaggagaaggagaagaacactcggttgctaggt
gctgcacagcagctgttcggccactgccaggcccagaaagaggagatcaagaggctcttc
cagcagaaactggatgagctgggcgtgaaggcgctgacctacaacgacctgatccaggcg
cagaaggagatttcggctcacaaccagcagctgagggaacagacggagcagctgcagaag
gacaacagggagctgagaagccagagcctgcagctgctcaaggctcggtgtgaggagctg
aagctggactggtccacgctgtcgctggagaacttgctgaaggagaagcaggccctgagg
acccagatctccgagaagcagaggcactgcctggagctgcagatcagcattgtggaactg
gagaagagccagcggcagcaggagctcctgcagctcaagtcttgcgtgccaccggatgat
gccctgtcggcgcacctacgcgggaaaggcgccctgggccgggagctggaggccgacccc
agccggctgcatcttgacctggactgccccaagttctccctgccccacttgagcagcgca
agcccagagctctccatgaatggccacgcggccagctacgaggtgtgcggcgcgctgagc
cggccctcgtccaagcagaacactccccagtacctggcctccccgctggaccaggaagtc
ataccctgcacccccagccacagcagccggccgaggctcgagaagatgtcgggcctggcc
ttgcccgactacacccggctctccccggccaagctggtgctgaggcggcacctgagccag
gaccacgtggccagtggcaaaacggcggccagcgagctgcacccgcgagctgagcacgcc
aaggagaacggccttccgtaccagagccctggcattgcgaacggcatcaagctgagccct
caggaccctcgaccctcatcccccatggccttccagatgacaggggagaggggcggcgag
aagggagtgaaggagcgcagctatgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccgctcagcaccgtgcagccgagcaagctgcccgtcagcatccctctggccagc
gtggtgctgcccagccgcgccgagaaagtgaggagcacccccagtcctgtgccgcagacc
cgagagtcctcgtccacacttgaaaagcagatgggcgctaatgcccacggcgctgcaagc
aaaggcctcacccctgctcctgcaggcttctacgcgggctcagtggctgtcagcggggcc
ctggcaggcagcccggcccccctcgctcccggagccgagcccggcgccttcgatgaggtc
tcgggctcgggaagcctgttcgccggcatggggccctgctccaccccgcagcacccgccc
ctgctgccgcagtcccgcggctctggtgcagcctcgcctgcccatccgctctgcgccagc
ccccggctcagcagtgccgcccagggcccgctccccgaggccagcaaaggggaccttccc
tccgaggccggcttctcagatcccgagggcgaagccaagaggagggtcgtcttcaccatc
tcggctggcggcattgccaagcagtcacctcccggcaaacccagccctctgcccacgggc
gcccgcggggacagtggccagggccacgggccggacggccgcaagcggggcaggaggaag
cgggcggcggctgggacccccggcttgagctccggcgtgtcgcccaagcgtcgggccctg
ccgtccgttgccggccttttcacgcagtcttcagggtccccgctgaacctcagctccatg
gtcagcaacattaatcagcctttggaaatcacggccatctcgtctcccgagagcctgaag
agctcccctgtcccttaccaggacaacgaccagccgcccatcctcaagaaggagaagccg
ttgagccagaccaacggggcccactactccccactgacctcagacgaggagcagggctcc
gaggacgagccaggcagcgccagaatcgagagaaaaattgcaacaatctccttagaaagc
aaatctcctccaaaaaccttggaaagcggtggtggcctggccgggaggaagccgacccct
gccagcgagcccaccaacagcagcaagtggaaatccaccttctcacccatttccgacctc
ggcctggccaagtgcgccgacagcccgctgcaggccggctccgccctgagccagaactcc
ctgttcgctttccggccccccctagaggagcccggcttggctgaagccaagctggctgcc
caccccaggaaaagcttttccagtgccctgtcgggggctggtgggctgagccccagcagc
aaccctcccaatggcttcaccttcagcgggggcctggccgccgacctcagtttacacagc
ttcagcgatggtgcttctctctcccacaaggtccccgaggcggccagcctgggcaccccc
ctgagcttccctgccccgcggggcaaggagggcagtgccgcagagtccggcgcctttgtg
aacaagaggcagctggaaggactggctggccccaagggcagggaggccggcgagctgggc
ctgccggcgtgcgggcccccggacaagcccttgctggtgcacagcaagccgggcaagggc
cgggaccgcgagcccgacttgaagaacggccacaacctcttcatttctgccgccactgtg
cctcccgggggcctcctcagcggcccgggcctcgccacggcggcgtcctcggcagtcagc
gcggccccctccgcccagacacaccgccccttcctgggcacctttgcccccggcccacag
ttcgccctgggtcccatgtccctgcaggccaacctgggctcgtccgtgctccagtccttg
ttcagctccgtgccggccgccgccggcctggtgcacgtctcgtccgctgcaaccagactg
accaactcgcacgccatgggcagcttttcctccggggtggcaggcggcgcagttggaggt
gtctttaaccacgcggtgccttccgcctccgcccatccgtttggagccagtttcggccgc
ggggctgcgtgtcgcagcgccacgctgagcctaagcccgctgcaggcggtggccggcgcc
cccgcgtcttcctttcaggccccgcccccgcccccaccggggcagcccgccctccccgca
ccccctccccctaacgccgccttgcctcctgcccccgcgctgctcccagctaactctgag
cccatgcttctgcagaacctcgcgtccctcccggctaaccaggctttcttgcccacctcc
tctgccgcctctctgcagcctgctaacgcctctctgtccatcaagctcgcctccctcccg
cacaaggccccccgcccctccttcacggtgcaccaccagcccctgcccgggctggccctg
gcccaggccgcgcccgtgatcccgcaggccagctccacggggccgtctgccgtgtgggtt
tcccttggcatgccgcctccgtatgccgcgcgccttgcgggggttaagccgagataa
DBGET
integrated database retrieval system
