Mirounga leonina (Southern elephant seal): 118006050
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Entry
118006050 CDS
T07472
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04010
MAPK signaling pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04218
Cellular senescence
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04270
Vascular smooth muscle contraction
mlx04530
Tight junction
mlx04713
Circadian entrainment
mlx04723
Retrograde endocannabinoid signaling
mlx04724
Glutamatergic synapse
mlx04725
Cholinergic synapse
mlx04726
Serotonergic synapse
mlx04727
GABAergic synapse
mlx04728
Dopaminergic synapse
mlx04911
Insulin secretion
mlx04912
GnRH signaling pathway
mlx04921
Oxytocin signaling pathway
mlx04924
Renin secretion
mlx04925
Aldosterone synthesis and secretion
mlx04927
Cortisol synthesis and secretion
mlx04929
GnRH secretion
mlx04930
Type II diabetes mellitus
mlx04934
Cushing syndrome
mlx04935
Growth hormone synthesis, secretion and action
mlx04973
Carbohydrate digestion and absorption
mlx05010
Alzheimer disease
mlx05020
Prion disease
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05031
Amphetamine addiction
mlx05207
Chemical carcinogenesis - receptor activation
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118006050 (CACNA1D)
04020 Calcium signaling pathway
118006050 (CACNA1D)
04024 cAMP signaling pathway
118006050 (CACNA1D)
04022 cGMP-PKG signaling pathway
118006050 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
118006050 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
118006050 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
118006050 (CACNA1D)
04929 GnRH secretion
118006050 (CACNA1D)
04912 GnRH signaling pathway
118006050 (CACNA1D)
04921 Oxytocin signaling pathway
118006050 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
118006050 (CACNA1D)
04924 Renin secretion
118006050 (CACNA1D)
04925 Aldosterone synthesis and secretion
118006050 (CACNA1D)
04927 Cortisol synthesis and secretion
118006050 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
118006050 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
118006050 (CACNA1D)
04270 Vascular smooth muscle contraction
118006050 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
118006050 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
118006050 (CACNA1D)
04727 GABAergic synapse
118006050 (CACNA1D)
04725 Cholinergic synapse
118006050 (CACNA1D)
04728 Dopaminergic synapse
118006050 (CACNA1D)
04726 Serotonergic synapse
118006050 (CACNA1D)
04723 Retrograde endocannabinoid signaling
118006050 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
118006050 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
118006050 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
118006050 (CACNA1D)
05020 Prion disease
118006050 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
118006050 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
118006050 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118006050 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
118006050 (CACNA1D)
05414 Dilated cardiomyopathy
118006050 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118006050 (CACNA1D)
04934 Cushing syndrome
118006050 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mlx04040
]
118006050 (CACNA1D)
Ion channels [BR:
mlx04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
118006050 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Motif
Other DBs
NCBI-GeneID:
118006050
NCBI-ProteinID:
XP_034854528
LinkDB
All DBs
Position
Unknown
AA seq
2170 aa
AA seq
DB search
MMMMMMMKNMHHQRQQQADHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADTDILAEEDPAPCAFSGNGRQCAANGTECRSGWAGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GGGENQGGCGSLWCWWKRRGTAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYHQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMAT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADKIVANSEESN
RISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQM
FGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPESDYNPGE
EYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSE
YDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLF
ALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFL
IQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEETK
REEEEDVFKRNGALLGNHVNHVNSDRRDPLQQTNTTHRPLHVQRPSVPPASDTERPLFPP
AGNSGCHSHHNHNSIGKQAPSSTNANLNNANMSKAAPGKRPSMGNLEHMSENGHPSSHKH
DREPPRRSSIKRTRYYETYIRSDSRDEQFPTICREDPEIRGYFRDSCCLEEQEYFSGEEG
FEDACSPTGARQNYSYYSRYPGGSWDFERPRGYHHPQGFLEDEDSPVCYDSRRSPRRRLL
PPTPTSHRRSSFNFECLRGQSSQEDVPPSPAFPHRTALPLHLMQQQIMAVAGLDSSKAQK
YSPSHSTRSWATPPATPPYRDWTPCYAPLIQVERPEALDQVNGSLPSLHRSSWYTDEPGI
SYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADA
CDLTIDEMESAASNLLNGTVYPQANGGVGPVSHRQDYELQDFGPGYSDEEPDPGRDEEDL
ADEMICITTL
NT seq
6513 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaacatgcaccatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgcc
agacaggccaaggctgcccaaactatgagcacctccgcacccccacctgtgggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctacatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattctggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaagtcaggaggcttcgatgtcaaagccctccgc
gcctttcgggtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgacacagatatcctggccgaagaggacccagcgccgtgtgcgttctca
gggaatggacgccagtgtgctgccaatggcaccgagtgtaggagtggctgggctggccca
aacggaggcatcaccaactttgataactttgcctttgccatgctcaccgtgtttcagtgc
atcaccatggagggctggacagacgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagagagaaggctaaagcccgggga
gatttccagaagctccgggagaagcagcagctggaggaggatctaaagggctacctggat
tggatcacccaagcagaagacattgatcctgagaacgaggaagaaggaggagaggaaagc
aaacgaaacaccagcatgcccaccagcgagaccgagtcggtgaacacagagaacgtgagt
ggcggaggcgagaaccaaggcggctgtgggagtctctggtgctggtggaaaagaagaggc
acggccaaggctgggccctctgggtgtcggcggtggggccaagccatctcaaaatccaag
ctcagccgacgctggcgtcgctggaaccgcttcaatcgcagaagatgtcgggctgctgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctctgagcactaccaccagcctgactggctgacgcagattcaagatatcgctaacaaa
gtcctcctggctctgttcacctgcgagatgctggtaaaaatgtatagcttgggtctccag
gcatatttcgtctctctctttaaccggtttgattgcttcgtggtgtgcggtggaattacc
gagaccatcttggtggagctggagatcatgtctcccctggggatctctgtgtttcggtgt
gtgcgcctcttaaggattttcaaggtgaccaggcactggacttccctgagcaacttagtg
gcctccttgttaaactccatgaagtccatcgcttcgctgttgcttctgctttttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggtggcaagtttaattttgacgaa
acgcagaccaagcggagcacctttgacaatttccctcaagcccttctgacagtcttccag
atcctgacaggagaagactggaacgctgtgatgtatgatggcattatggcctatggcggc
ccgtcctcctcagggatgatcgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaatgtcttcttggccatcgctgtagacaatctggctgatgctgaaagt
ttgaatactgcccagaaagaggaagctgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggagaataaaaagaacaacaaaccagaagtcaaccagatagccaacagtgac
aataaggttacaattgatgactatcgagaagaggatgaagacaaggacccctacccacct
tgtgatgtgccagtaggggaagaggaagaggaggaggaggaggatgaacctgaggttcct
gctggcccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccccatt
cctgaagggagcgcgttcttcattctgagcaagaccaacccgatccgcgtgggctgccac
aagctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagc
gccgcccttgccgccgaggaccccatccgcagccactccttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatggcgact
tttggagctttcctccacaaaggggctttctgcaggaactacttcaatctgctggatatg
ctggttgtcggggtgtccctggtatcatttgggatccaatccagtgccatctccgttgtg
aagattctgagggtcttaagggtcctgcggccgctcagggcgatcaacagagcgaaagga
cttaagcacgtggtccagtgtgtcttcgtggccatccggaccattggcaacatcatgatc
gtcaccacccttctccagttcatgttcgcctgcatcggggtccagttgttcaagggaaag
ttctatcgctgtacagatgaagccaaaagtaaccccgaagagtgcagggggcttttcatc
ctctacaaggatggggatgttgataaccctgtggtccgtgagaggatctggcaaaatagt
gatttcaacttcgacaacgtcctttctgctatgatggcgctgttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcaaatggagagaatgtgggcccc
atctacaaccaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtggct
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacatttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgttgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactatgagcagtccaagatgtttaatgacgccatggacattctg
aacatggtcttcactggggtgttcaccgtcgagatggttttgaaagtcatcgcgtttaaa
cctaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggccctcagcgaagccgacaaaattgtagcgaactctgaagagagcaat
agaatctccatcacctttttccgtcttttccgagtgatgcggttggtgaagcttctcagc
aggggggaaggcatccggacgttgctgtggacttttataaagtcctttcaggcactgccc
tatgtagccctcctcatagccatgttgttcttcatctacgcggtgattggcatgcagatg
tttgggaaggttgctatgagagataacaaccagatcaacaggaacaacaatttccagacc
tttccccaggcggtgctgctgctcttcaggtgtgccacgggtgaagcctggcaggagatc
atgctggcctgcctcccggggaagctctgtgaccccgagtcggactataaccccggggag
gagtacacgtgtgggagcaacttcgccattgtttatttcatcagtttttacatgctctgc
gcgtttctgatcattaacctgtttgtggctgtcatcatggacaactttgattatctgacc
cgggactggtctattctggggcctcaccatttagatgaattcaaaagaatatggtcggag
tatgaccctgaggcgaaaggaaggataaaacacctcgatgtggtcactctgctccgccgc
atccagcctccactggggtttgggaaattatgcccacacagagtagcctgtaagagacta
gtggccatgaacatgcctctcaacagtgatgggacggtcatgtttaatgcaaccctgttt
gctttggttcgaacggctcttaaaatcaagacggaagggaacctggaacaagctaatgaa
gaactccgagctgtgatcaagaaaatctggaagaaaactagcatgaaactgcttgaccaa
gttgtccctccagctggtgatgatgaggtaaccgtggggaagttctatgccactttcctg
atacaggactactttaggaaattcaagaaacggaaagaacaaggcctggtgggaaaatac
cctgcgaagaacaccaccattgccctacaggcaggattaaggacactgcatgacattggg
ccagaaatccggcgtgctatatcatgtgatttgcaagatgacgagccggaggaaacaaaa
cgagaagaagaagaagatgtattcaaaagaaatggtgccctgcttggaaaccatgtcaat
catgttaatagtgataggagagacccccttcagcagaccaataccacccaccgtcccctg
catgtccaaaggccttcagttccacctgcaagtgatactgagagaccgctgtttcctcca
gcaggaaattcggggtgtcatagccatcataaccataattccataggaaagcaagctccc
agctcaacaaatgccaatctcaataatgccaatatgtccaaagctgcccctggaaagcgg
cccagcatggggaaccttgagcatatgtctgaaaatgggcatccctcctcccacaagcat
gaccgggagcctccaagaaggtccagtattaaaagaacccgctattatgaaacttacatt
aggtctgactcgagggatgagcagttccccactatctgccgggaagatccagagatccgt
ggctacttcagggactcctgctgcttggaggaacaggagtatttcagcggtgaggagggc
tttgaggatgcctgctcgccgaccggggccaggcaaaactacagctactacagccgatac
ccaggtggcagctgggacttcgagcggccccgaggctaccatcacccccaaggcttcttg
gaggatgaggactcgcctgtttgctatgattcccggagatctccaaggagacgcctacta
cctcccaccccgacatcccaccggagatcctccttcaacttcgagtgcctgcgcgggcag
agcagccaggaggacgtcccgccgtcccccgccttcccccaccgcacagccctgcctctg
cacctgatgcagcaacagatcatggcagttgcgggcctggattccagtaaagcccagaag
tactcaccgagccactcgacccggtcatgggccacccctccggcgacccctccgtaccgg
gactggacaccgtgctacgcgcccctgatccaggtggagcggccggaggccctggaccag
gtcaatggcagcctgccgtccctgcaccggagctcctggtacacggacgagcctggcatc
tcgtaccgaacgttcacaccagccagcctgactgtccccagcagcttccgcaacaagaac
agtgacaagcagaggagcgcagacagcttggtggaggcggtcctgatatctgaaggctta
ggacggtatgcaagggacccaaaatttgtatcggcaacaaaacacgaaatcgccgatgcc
tgcgacctgaccatcgacgagatggaaagtgcagccagcaacctgctcaacgggacggtg
tatccccaggctaacgggggcgtgggccccgtctcccaccggcaggactatgagctccag
gacttcgggccaggctatagcgatgaagagcctgaccccggaagagatgaggaagacctg
gcagatgaaatgatctgcatcaccaccctgtag
DBGET
integrated database retrieval system
