Mirounga leonina (Southern elephant seal): 118006072
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Entry
118006072 CDS
T07472
Symbol
NOTCH3
Name
(RefSeq) neurogenic locus notch homolog protein 3 isoform X1
KO
K20995
Notch 3
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01522
Endocrine resistance
mlx04330
Notch signaling pathway
mlx04371
Apelin signaling pathway
mlx04658
Th1 and Th2 cell differentiation
mlx04919
Thyroid hormone signaling pathway
mlx05165
Human papillomavirus infection
mlx05200
Pathways in cancer
mlx05206
MicroRNAs in cancer
mlx05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
118006072 (NOTCH3)
04371 Apelin signaling pathway
118006072 (NOTCH3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
118006072 (NOTCH3)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118006072 (NOTCH3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118006072 (NOTCH3)
05206 MicroRNAs in cancer
118006072 (NOTCH3)
09162 Cancer: specific types
05224 Breast cancer
118006072 (NOTCH3)
09172 Infectious disease: viral
05165 Human papillomavirus infection
118006072 (NOTCH3)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
118006072 (NOTCH3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_TEN
EGF_CA
Ank_2
Ank
EGF_2
Notch
NODP
Ank_4
NOD
Ank_3
Ank_5
EGF_Teneurin
EGF_3
cEGF
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
118006072
NCBI-ProteinID:
XP_034854567
LinkDB
All DBs
Position
Unknown
AA seq
2331 aa
AA seq
DB search
MGPGTRGRRCRRPMSPPPPLPPVRALPLLLLLAGPGAAAPPCLDGSPCMNGGRCTQLPSR
EAACLCPPGWVGERCQLEDPCHSGPCAGRGICQSSVVAGTARFSCRCPRGFRGPDCSLPD
PCLSSPCTHGARCSVGPDGRYICSCPPGYQGRSCRSDVDECRVGGPCRHGGTCLNTPGSF
RCQCPAGYTGPLCENAAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCP
GHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCV
CVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCH
EDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGR
GYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDMDECQSSPCVNG
GVCKDRVNGFSCTCPSGFSGAMCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTL
CERNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLV
DKYLCRCPPGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGMKLPSCSPGP
LCNVEINECASSPCGDGGSCMDGENGFHCLCPPGSLPPLCLPPSHPCAQEPCSHGVCHDA
PGGFRCVCEPGWSGPRCSQSLARDACESQPCQSGGTCTSDGMGFHCTCPPGVQGRQCELP
SPCAPNPCEHGGHCESAPGQLPVCSCPPGWQGPRCQQDVDECAGPSPCGSHGTCTNLEGS
FSCTCHRGYSGPSCDQDIDDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECL
SSPCGPGTCTDHVASFTCTCPPGYGGFHCEKDLPDCSPSSCFHGGTCVDGVSSFSCQCRP
GYTGAHCQHEADPCLSRPCLHGGVCTAAHPGFRCTCPEGFTGTQCQTLVDWCSRAPCQNG
GRCAPTGATFYCLCPPGWSGRLCDIRSVPCREAAAQLGVRLEELCQTGGRCVDKDNSHYC
VCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYVGGYVCECPAGYTGDNCEDDVDECASQP
CQHGGFCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDQGPRCLHNGTCVDLVGGFR
CTCPPGYTGLRCEADINECHPGACHDAHTRDCLQDLGGGFRCICRAGFTGPRCQTVLSPC
ESQPCQHGGQCRPSPGPGGVLTFTCHCIPPFWGPRCERVARSCRELQCPAGVPCQQTVRG
PRCACPPGLSGPACRGVRGSPPGAANASCVASPCLHGGSCRPAPLAPFFRCACAPGWAGA
RCEAPAAAPEAPEEPLCPSAACEAKSGDKRCDRECNSPGCGWDGGDCSLSVGDPWRQCAA
LQCWRLFNNSRCDPACSSPACLYDNFDCRAGGRERACNPVYEKYCADHFADGRCDQGCNT
EECGWDGLDCAGEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSGILRTSLRFRLDEH
GQAMVFPYHRPGPGSESRNRRELAPEVIGSVVMLEIDNRLCLQSPENDHCFPDAQSAADY
LGALSAVERLDFPYPLRAVRGEPLELPEPSVPLLPLLAASAVFLLVILVLGVMVARRKRE
HSTLWFPEGFALHKDVAAGHKGRREPVGQDALGMKNMAKSESLMGEVATDWMDTECPEAK
RLKVEEPCVGAEDAVDCRQWTQHHLVAADIRVAPAMALTPPQGDVDADGMDVNVRGPDGF
TPLMLASFCGGALEPMPTEEDEAEDTSASIISDLICQGAQLGARTDRTGETALHLAARYA
RADAAKRLLDAGADTNAQDHSGRTPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTAL
ILAARLAVEGMVEELIASHADVNAVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDS
KEETPLFLAAREGSYEAAKLLLDHFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGP
RSPHGPHGLGPLLCPPGAFLPGLKVAQSGGKKSRRPPGKTGLGPQGTRGRGKKLTLACPG
PLAESSVTLSPVDSLDSPRPFGGPPASPGGFSLEGPYAAATATAVSLAQIGGAGRAGLGR
QPPGGCVLSLGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPP
YLAAPGHAEEYPAAGAHGSPPKARFLRVPSEHPYLTPSPESPEHWASPSPPSLSDWSDST
PSPATATGPTATAAGALPAQPLPLSVPGPLAQAQTQLGPQPEVTPKRQVLA
NT seq
6996 nt
NT seq
+upstream
nt +downstream
nt
atggggccggggacccggggccgccgctgccgccgcccgatgtcgccgccgccaccactg
ccgcccgtgcgggcgctgcccctgttgctactgctagcggggcccggggctgcagcaccc
ccttgcctggacgggagcccgtgtatgaatggaggtcgctgcacccagctgccctcccgg
gaggctgcctgcctgtgcccaccaggatgggtgggcgagcggtgccagctggaagacccc
tgccattcgggcccctgtgctggccgtggcatctgccagagctccgtggtggcaggcacc
gcccggttctcctgccgctgcccccgtggcttccgaggtcccgactgctccctgccggac
ccctgcctcagcagtccctgtacccatggtgcccgctgctcggtggggcccgatggccgc
tacatctgctcctgcccacctggctaccagggccgcagctgccgaagcgacgtggatgag
tgccgggtgggagggccctgccgccatggtggcacctgcctcaacacgcctggttccttc
cgctgccagtgcccagctggctacacggggccactgtgtgagaacgctgcggtgccctgc
gccccctcgccgtgccgcaatgggggcacatgtagacagagtggcgatctcacctatgac
tgcgcctgccttcctgggttcgagggccagaactgtgaagtgaatgtggacgactgtcca
ggacaccgatgtctaaatggggggacatgtgtggatggcgtcaacacctacaactgccag
tgccctcctgaatggacaggccaattctgcacggaggatgtggacgaatgtcagctgcag
cccaacgcttgccacaatgggggcacctgcttcaacactctgggtggccacagctgtgtg
tgtgtcaatggctggacaggcgagagctgcagtcagaatatcgatgactgtgccacggct
gtgtgcttccatggggccacctgccatgaccgtgtggcctcgttctactgtgcctgtccc
atgggcaagactgggcttctgtgtcatctggatgacgcttgcgtcagcaacccctgtcac
gaggatgctatctgcgacacgaaccccgtgaatggccgggccatctgcacctgtccacca
ggcttcaccggcggggcatgtgaccaggatgtggatgagtgctccattggtgccaaccca
tgtgagcacctgggccggtgcgtgaacacacagggctcgttcctgtgccagtgcggccgt
ggctacactggcccgcgctgtgagaccgacgtcaacgagtgcctatccgggccctgccgc
aaccaggccacgtgcctcgaccgcataggccagttcacctgcatctgcatggcaggcttt
acaggcacctattgtgaggtggacatggatgagtgtcaaagcagcccgtgtgtcaatggt
ggggtctgcaaggacagagtcaacggcttcagctgcacctgcccctcaggcttcagtggg
gccatgtgtcagctggatgtggatgagtgcgcaagcacaccctgccggaatggagccaag
tgcgtggaccagcccgatggctacgaatgccgctgtgcagagggcttcgagggcacgctg
tgtgagcgcaacgtggacgactgctccccggacccgtgccaccatgggcgctgtgtggac
ggcattgccagcttctcgtgtgcctgcgccccgggatacacaggcacgcgctgtgagagc
caggtggacgagtgccgcagccagccctgccgccacgggggcaaatgtctagacttggtg
gacaaatatctctgccgctgccctcctggcaccacaggagtgaactgcgaggtgaacatt
gatgactgtgccagcaacccctgcacctttggagtctgccgggatggcatcaaccgctat
gactgtgtctgccagcctggcttcacagggatgaagttgccttcgtgctctccagggccc
ctttgcaacgtggagatcaacgagtgtgcgtccagtccgtgcggtgatggaggttcctgt
atggatggggaaaatggcttccactgcctctgccctcccggctccctgcccccactctgc
ctccccccgagccatccctgtgcccaagaaccttgcagtcatggtgtctgccacgatgca
cccggagggttccgctgtgtgtgtgagcctggctggagtggtccccgatgcagccagagc
cttgctcgagatgcctgcgaatcgcagccctgccagtccggcggcacctgcaccagtgat
ggaatgggcttccattgtacctgtccccctggtgtccagggccgtcagtgtgagctgcca
tccccctgtgccccgaacccctgtgagcacgggggccactgtgagtctgccccgggccag
ctgcctgtctgctcctgcccccctggctggcaaggcccacgatgccagcaggatgtggat
gaatgtgctggcccctcaccctgtggctcccacggtacctgcaccaacctggaggggagt
ttcagctgtacctgccatagggggtatagtggcccttcctgtgatcaggacatcgatgac
tgtgaccccaacccctgcctgaatggtggctcctgtcaggatggcgtgggctccttttcg
tgctcctgcctccctggcttcgctggtccccgttgtgcccgagatgtggacgagtgtctc
agcagcccctgtggcccgggcacctgcaccgaccatgtggcctcctttacctgcacgtgc
ccacctggttatggaggtttccactgtgaaaaggacctaccggactgcagccccagctcc
tgcttccatggcgggacctgcgtggacggcgtgagctcgttcagctgccagtgccgcccg
ggctacactggcgcacactgccagcacgaggccgacccctgcctctctcggccctgtctg
cacgggggcgtctgcactgctgcccaccctggcttccgctgcacctgcccggagggcttc
actggcacgcagtgccagacgctggtagactggtgcagccgcgcgccctgtcagaacggg
ggtcgctgcgccccgaccggggccaccttctactgcctttgccctccggggtggagcggc
cgcctctgtgacatccggagtgtgccctgcagggaggccgcagcccagctcggggtacgg
ctggaagagctgtgtcagacaggtgggcggtgtgtggataaggacaattcccactactgc
gtgtgcccagaaggccgcacgggcagccactgtgagcaggaggtggacccctgcttggcc
cagccctgccaacatgggggcacctgccgaggctacgtggggggttatgtgtgtgagtgt
ccagctggctacacgggggacaactgtgaggatgatgtagacgagtgtgcctcccagccc
tgccagcacggtggcttctgcattgaccttgtggcccgctatctctgctcctgcccccca
ggaacactgggcgtgctctgtgagattaatgaggacgactgtggcccaggcccacccctg
gaccagggcccccggtgcctgcacaatggtacctgtgtggacctggtgggtggcttccgc
tgcacctgcccccccgggtacactggcttgcgctgtgaggcggacatcaatgagtgtcac
ccgggtgcctgccatgatgcacacactcgggattgtctgcaggacctaggtgggggcttc
cgctgcatttgccgagcaggcttcacaggtccccgctgtcagactgtcctgtctccctgc
gagtcccagccgtgccagcacggaggccagtgccgtcccagcccaggccctgggggtgtg
ctgacatttacctgtcactgcattccgccgttctggggcccgcgttgcgagcgggtggcg
cgctcctgccgggagctgcagtgtccggcgggcgtcccgtgccagcagacggtccgtggg
ccgcgctgcgcctgtccccccgggctgtcggggcccgcctgccggggcgtgcgggggtcg
ccgccgggggccgccaacgccagctgcgtggcctccccgtgcctccacggtggctcctgc
cgcccagcgccgctcgcccccttcttccgctgcgcgtgcgcgccgggctgggccggagcg
cgctgcgaggcgcccgcggcggcgcccgaggccccggaggagcctctgtgcccgagcgca
gcctgcgaggccaagagcggggacaagcgctgtgaccgcgagtgcaacagcccgggctgc
ggctgggacggcggcgactgctcgctgagcgtgggcgacccctggcggcagtgcgcggcg
ctgcagtgctggcgcctcttcaacaacagtcgctgtgaccccgcctgcagctcgcccgcc
tgcctctatgacaacttcgattgccgcgcgggcggccgcgagcgcgcctgcaacccagtg
tacgagaagtactgtgcggaccactttgccgatggccgctgcgaccagggctgcaacacg
gaggagtgcggctgggacgggctggactgtgcgggcgaggtgccggccctgctggcccgc
ggcgtgctggtgctcaccgtgctgctcccgcccgaggagctgctgcgctccagcgccgac
ttcctgcagcggctcagcggcatcctgcgcacctcgctgcgcttccgcctggacgaacac
ggccaggccatggtcttcccttaccaccggcccggtcctggctccgaatcccggaaccgg
cgggagctggcccccgaggtgatcggctctgtggtgatgctggagattgacaaccggctg
tgcctgcagtcgcccgagaatgaccactgcttccccgatgcgcagagcgcggccgactac
ctgggagcgctgtcggccgtggagcgccttgacttcccgtacccgctgcgcgccgtgcgg
ggggagccgctggagctgccagagccaagcgtgcccttgcttcccctgctggccgccagc
gccgtcttcctgctggtcatcctcgtcctgggtgtcatggtggcccggcgcaagcgcgag
cacagcaccctctggttccccgagggcttcgcgctccacaaggatgtggctgccggccac
aagggccggcgggagcccgtgggccaagacgcgctgggcatgaagaacatggccaagagc
gagagtctgatgggggaggtggccacagactggatggacacggagtgcccagaggctaag
cgactgaaggtagaggagccctgtgtgggggctgaggatgctgtggattgccgccagtgg
acccaacaccacctggttgccgcagacatccgtgtggcaccagccatggcgctgacaccc
ccgcagggcgatgtggatgctgatggcatggatgtcaatgtgcgaggcccagatggcttc
actccactgatgctggcctccttctgtgggggggccctggagccaatgcccactgaggag
gatgaggcagaagacacatcagccagcatcatctcagacttgatctgccagggagcccag
cttggggcacggactgaccgcacaggcgagacagccctgcacctggctgcccgctacgcc
cgggctgatgcagccaagcggttgctggatgctggggcagacaccaatgcccaggaccac
tcagggcgcactcctttgcacactgcagtcaccgcggatgcccagggcgtgttccagatt
ctcatccggaaccgctccacagacctggatgcccgcatggcggatggctctacggcacta
attctggccgcccgcctggcggtggagggcatggtggaagagctcattgccagccatgct
gatgtcaatgctgtggatgagcttgggaaatcagccttacactgggcagcagccgtcaac
aatgtggaggccaccttggccctgctcaaaaatggagccaacaaggacatgcaggatagc
aaggaggaaactccactgtttctggccgcccgtgagggcagctatgaggctgccaaactg
ctgctggaccactttgccaaccgtgagatcacagaccacctggacaggctgccgcgggat
gtggcccaggagcggctacaccaggacatcgtgcgtctgctggaccagcccagtgggccc
cgcagccctcacggtcctcatggcctggggcccctcctctgtccacccggggccttcctc
cctggcctcaaggtggcacagtcggggggcaagaagagccggaggccaccggggaagacg
ggtctggggccacagggcacccgggggcggggcaagaagctgacactggcctgcccgggt
cccctggctgagagctcagtcacgctgtcgcccgtggactcgctggactccccgcggccc
ttcggtgggccccctgcgtcccctggtggcttctccctcgaggggccctatgcagcagcc
accgccacggccgtgtccctggctcagattggtggcgcgggccgggcgggtttagggcgc
cagccccctgggggctgcgtgctcagcttgggtttgctgaaccccgtggctgttcccctc
gactgggcccggctgcctccacctgccccgccaggcccctcattcctgctgccgctggcg
ccgggaccccagctgctgaatcccgggacccccgtgtccccccaggagcggcccccgcca
tatctggcagccccgggacacgccgaggagtacccggcagccggcgcccacggcagcccc
cccaaggcccgcttcctgagggttccgagtgagcacccttacctgaccccatcccccgag
tcccccgagcactgggccagcccctcacctccctccctctcggactggtcagactccacg
cccagcccagccactgccaccgggcctacggccacagccgctggggcgttgcctgcccag
ccgctccccctttccgtcccaggccccctagctcaggcccagacccagctggggccccaa
ccggaagtcacccccaagaggcaggtgttggcctga
DBGET
integrated database retrieval system
