KEGG   Mirounga leonina (Southern elephant seal): 118007057
Entry
118007057         CDS       T07472                                 
Symbol
GSK3B
Name
(RefSeq) glycogen synthase kinase-3 beta isoform X1
  KO
K03083  glycogen synthase kinase 3 beta [EC:2.7.11.26]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01521  EGFR tyrosine kinase inhibitor resistance
mlx04012  ErbB signaling pathway
mlx04062  Chemokine signaling pathway
mlx04110  Cell cycle
mlx04150  mTOR signaling pathway
mlx04151  PI3K-Akt signaling pathway
mlx04310  Wnt signaling pathway
mlx04340  Hedgehog signaling pathway
mlx04360  Axon guidance
mlx04390  Hippo signaling pathway
mlx04510  Focal adhesion
mlx04550  Signaling pathways regulating pluripotency of stem cells
mlx04657  IL-17 signaling pathway
mlx04660  T cell receptor signaling pathway
mlx04662  B cell receptor signaling pathway
mlx04722  Neurotrophin signaling pathway
mlx04728  Dopaminergic synapse
mlx04910  Insulin signaling pathway
mlx04916  Melanogenesis
mlx04917  Prolactin signaling pathway
mlx04919  Thyroid hormone signaling pathway
mlx04931  Insulin resistance
mlx04932  Non-alcoholic fatty liver disease
mlx04934  Cushing syndrome
mlx04935  Growth hormone synthesis, secretion and action
mlx04936  Alcoholic liver disease
mlx05010  Alzheimer disease
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05135  Yersinia infection
mlx05160  Hepatitis C
mlx05162  Measles
mlx05163  Human cytomegalovirus infection
mlx05165  Human papillomavirus infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05200  Pathways in cancer
mlx05210  Colorectal cancer
mlx05213  Endometrial cancer
mlx05215  Prostate cancer
mlx05217  Basal cell carcinoma
mlx05224  Breast cancer
mlx05225  Hepatocellular carcinoma
mlx05226  Gastric cancer
mlx05415  Diabetic cardiomyopathy
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    118007057 (GSK3B)
   04310 Wnt signaling pathway
    118007057 (GSK3B)
   04340 Hedgehog signaling pathway
    118007057 (GSK3B)
   04390 Hippo signaling pathway
    118007057 (GSK3B)
   04151 PI3K-Akt signaling pathway
    118007057 (GSK3B)
   04150 mTOR signaling pathway
    118007057 (GSK3B)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    118007057 (GSK3B)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118007057 (GSK3B)
   04550 Signaling pathways regulating pluripotency of stem cells
    118007057 (GSK3B)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    118007057 (GSK3B)
   04657 IL-17 signaling pathway
    118007057 (GSK3B)
   04662 B cell receptor signaling pathway
    118007057 (GSK3B)
   04062 Chemokine signaling pathway
    118007057 (GSK3B)
  09152 Endocrine system
   04910 Insulin signaling pathway
    118007057 (GSK3B)
   04917 Prolactin signaling pathway
    118007057 (GSK3B)
   04935 Growth hormone synthesis, secretion and action
    118007057 (GSK3B)
   04919 Thyroid hormone signaling pathway
    118007057 (GSK3B)
   04916 Melanogenesis
    118007057 (GSK3B)
  09156 Nervous system
   04728 Dopaminergic synapse
    118007057 (GSK3B)
   04722 Neurotrophin signaling pathway
    118007057 (GSK3B)
  09158 Development and regeneration
   04360 Axon guidance
    118007057 (GSK3B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118007057 (GSK3B)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118007057 (GSK3B)
   05225 Hepatocellular carcinoma
    118007057 (GSK3B)
   05226 Gastric cancer
    118007057 (GSK3B)
   05217 Basal cell carcinoma
    118007057 (GSK3B)
   05215 Prostate cancer
    118007057 (GSK3B)
   05213 Endometrial cancer
    118007057 (GSK3B)
   05224 Breast cancer
    118007057 (GSK3B)
  09172 Infectious disease: viral
   05160 Hepatitis C
    118007057 (GSK3B)
   05162 Measles
    118007057 (GSK3B)
   05163 Human cytomegalovirus infection
    118007057 (GSK3B)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118007057 (GSK3B)
   05165 Human papillomavirus infection
    118007057 (GSK3B)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    118007057 (GSK3B)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118007057 (GSK3B)
   05020 Prion disease
    118007057 (GSK3B)
   05022 Pathways of neurodegeneration - multiple diseases
    118007057 (GSK3B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118007057 (GSK3B)
   05415 Diabetic cardiomyopathy
    118007057 (GSK3B)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    118007057 (GSK3B)
   04932 Non-alcoholic fatty liver disease
    118007057 (GSK3B)
   04931 Insulin resistance
    118007057 (GSK3B)
   04934 Cushing syndrome
    118007057 (GSK3B)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    118007057 (GSK3B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118007057 (GSK3B)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:mlx03036]
    118007057 (GSK3B)
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.26  tau-protein kinase
     118007057 (GSK3B)
Protein kinases [BR:mlx01001]
 Serine/threonine kinases: CMGC group
  GSK family [OT]
   118007057 (GSK3B)
Chromosome and associated proteins [BR:mlx03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    118007057 (GSK3B)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kinase-like Kdo APH
Other DBs
NCBI-GeneID: 118007057
NCBI-ProteinID: XP_034855970
LinkDB
Position
Unknown
AA seq 433 aa
MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK
VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG
EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR
DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV
WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP
WTKDSSGTGHFTSGVRVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPN
VKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIQAAASTPTNATAASDANAGDRGQ
TNNAASASASNST
NT seq 1302 nt   +upstreamnt  +downstreamnt
atgtcagggcggcccagaaccacctcctttgcggagagctgcaagccagtgcagcagcct
tcagcttttggcagcatgaaagttagcagagacaaggatggcagcaaggtgactacagtg
gtggcaactcctgggcagggtccagataggccacaagaagtcagctatacagacactaaa
gtgattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgattcaggagaa
ctggttgccatcaagaaggtcttacaggacaagagatttaagaaccgagagctccaaatc
atgagaaagctagatcactgtaacatagtccgattgcgttatttcttctactcaagtggt
gagaagaaagatgaagtctatcttaatctggtgctggactatgttccggaaacagtatac
agagttgccagacactatagtcgagccaaacagacgctccctgtgatctatgtcaagttg
tatatgtatcagctgttccgaagtttagcctatatccattcctttggaatatgccatcgg
gatattaaaccacagaacctcttgttggatcctgatacagctgtcttaaaactctgtgac
tttggaagtgcaaagcagctggtccgcggagaacccaatgtttcgtatatctgttctcgg
tactatagggcaccagagttgatctttggagccactgattatacctctagtatagacgta
tggtctgcaggctgtgtgttggctgagctgttgctaggacaaccaatatttccaggggac
agtggtgtggatcaattggtggaaataatcaaggtcctggggacaccaacaagggagcaa
attagagaaatgaacccaaactacacagaattcaaattccctcaaattaaggcacatcct
tggactaaggattcgtcaggaacaggacatttcacctcaggagtgcgggtcttccgaccc
cggactccaccggaagcaattgcactgtgtagccgtctgctggagtatacaccaactgcc
cgattgacaccactggaagcttgtgcacattcattttttgatgaattaagggacccaaat
gtcaaactaccaaatgggcgagacacacctgcactcttcaacttcaccactcaagaactg
tcaagtaatccacctctagctaccatccttattcctcctcatgctcggattcaagcagct
gcttcaacccctacaaatgccacagcagcctcagatgctaatgccggagaccgtggacag
accaacaacgctgcttctgcatcagcttccaactccacctga

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