KEGG   Mirounga leonina (Southern elephant seal): 118010368
Entry
118010368         CDS       T07472                                 
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx01522  Endocrine resistance
mlx04010  MAPK signaling pathway
mlx04012  ErbB signaling pathway
mlx04014  Ras signaling pathway
mlx04024  cAMP signaling pathway
mlx04068  FoxO signaling pathway
mlx04071  Sphingolipid signaling pathway
mlx04137  Mitophagy - animal
mlx04140  Autophagy - animal
mlx04141  Protein processing in endoplasmic reticulum
mlx04210  Apoptosis
mlx04215  Apoptosis - multiple species
mlx04217  Necroptosis
mlx04310  Wnt signaling pathway
mlx04380  Osteoclast differentiation
mlx04510  Focal adhesion
mlx04530  Tight junction
mlx04620  Toll-like receptor signaling pathway
mlx04621  NOD-like receptor signaling pathway
mlx04622  RIG-I-like receptor signaling pathway
mlx04625  C-type lectin receptor signaling pathway
mlx04657  IL-17 signaling pathway
mlx04658  Th1 and Th2 cell differentiation
mlx04659  Th17 cell differentiation
mlx04660  T cell receptor signaling pathway
mlx04664  Fc epsilon RI signaling pathway
mlx04668  TNF signaling pathway
mlx04722  Neurotrophin signaling pathway
mlx04723  Retrograde endocannabinoid signaling
mlx04728  Dopaminergic synapse
mlx04750  Inflammatory mediator regulation of TRP channels
mlx04910  Insulin signaling pathway
mlx04912  GnRH signaling pathway
mlx04914  Progesterone-mediated oocyte maturation
mlx04917  Prolactin signaling pathway
mlx04920  Adipocytokine signaling pathway
mlx04926  Relaxin signaling pathway
mlx04930  Type II diabetes mellitus
mlx04931  Insulin resistance
mlx04932  Non-alcoholic fatty liver disease
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx04935  Growth hormone synthesis, secretion and action
mlx04936  Alcoholic liver disease
mlx05010  Alzheimer disease
mlx05012  Parkinson disease
mlx05016  Huntington disease
mlx05017  Spinocerebellar ataxia
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05132  Salmonella infection
mlx05133  Pertussis
mlx05135  Yersinia infection
mlx05142  Chagas disease
mlx05145  Toxoplasmosis
mlx05152  Tuberculosis
mlx05161  Hepatitis B
mlx05162  Measles
mlx05166  Human T-cell leukemia virus 1 infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05169  Epstein-Barr virus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05171  Coronavirus disease - COVID-19
mlx05200  Pathways in cancer
mlx05208  Chemical carcinogenesis - reactive oxygen species
mlx05210  Colorectal cancer
mlx05212  Pancreatic cancer
mlx05231  Choline metabolism in cancer
mlx05415  Diabetic cardiomyopathy
mlx05417  Lipid and atherosclerosis
mlx05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    118010368
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118010368
   04012 ErbB signaling pathway
    118010368
   04014 Ras signaling pathway
    118010368
   04310 Wnt signaling pathway
    118010368
   04668 TNF signaling pathway
    118010368
   04068 FoxO signaling pathway
    118010368
   04071 Sphingolipid signaling pathway
    118010368
   04024 cAMP signaling pathway
    118010368
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    118010368
   04137 Mitophagy - animal
    118010368
  09143 Cell growth and death
   04210 Apoptosis
    118010368
   04215 Apoptosis - multiple species
    118010368
   04217 Necroptosis
    118010368
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    118010368
   04530 Tight junction
    118010368
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    118010368
   04621 NOD-like receptor signaling pathway
    118010368
   04622 RIG-I-like receptor signaling pathway
    118010368
   04625 C-type lectin receptor signaling pathway
    118010368
   04660 T cell receptor signaling pathway
    118010368
   04658 Th1 and Th2 cell differentiation
    118010368
   04659 Th17 cell differentiation
    118010368
   04657 IL-17 signaling pathway
    118010368
   04664 Fc epsilon RI signaling pathway
    118010368
  09152 Endocrine system
   04910 Insulin signaling pathway
    118010368
   04920 Adipocytokine signaling pathway
    118010368
   04912 GnRH signaling pathway
    118010368
   04914 Progesterone-mediated oocyte maturation
    118010368
   04917 Prolactin signaling pathway
    118010368
   04926 Relaxin signaling pathway
    118010368
   04935 Growth hormone synthesis, secretion and action
    118010368
  09156 Nervous system
   04728 Dopaminergic synapse
    118010368
   04723 Retrograde endocannabinoid signaling
    118010368
   04722 Neurotrophin signaling pathway
    118010368
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    118010368
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118010368
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118010368
   05208 Chemical carcinogenesis - reactive oxygen species
    118010368
   05231 Choline metabolism in cancer
    118010368
  09162 Cancer: specific types
   05210 Colorectal cancer
    118010368
   05212 Pancreatic cancer
    118010368
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118010368
   05170 Human immunodeficiency virus 1 infection
    118010368
   05161 Hepatitis B
    118010368
   05171 Coronavirus disease - COVID-19
    118010368
   05162 Measles
    118010368
   05167 Kaposi sarcoma-associated herpesvirus infection
    118010368
   05169 Epstein-Barr virus infection
    118010368
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    118010368
   05135 Yersinia infection
    118010368
   05133 Pertussis
    118010368
   05152 Tuberculosis
    118010368
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    118010368
   05142 Chagas disease
    118010368
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118010368
   05012 Parkinson disease
    118010368
   05016 Huntington disease
    118010368
   05017 Spinocerebellar ataxia
    118010368
   05020 Prion disease
    118010368
   05022 Pathways of neurodegeneration - multiple diseases
    118010368
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118010368
   05418 Fluid shear stress and atherosclerosis
    118010368
   05415 Diabetic cardiomyopathy
    118010368
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    118010368
   04936 Alcoholic liver disease
    118010368
   04932 Non-alcoholic fatty liver disease
    118010368
   04931 Insulin resistance
    118010368
   04933 AGE-RAGE signaling pathway in diabetic complications
    118010368
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    118010368
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118010368
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     118010368
Protein kinases [BR:mlx01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   118010368
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 118010368
NCBI-ProteinID: XP_034860483
LinkDB
Position
Unknown
AA seq 330 aa
MFLLFFLQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTVLKRYQNLKPIGSGA
QGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQK
TLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSN
IVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMG
EMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFP
DSLFPADSEHNKLKGMPIRDNFRTTVRVMD
NT seq 993 nt   +upstreamnt  +downstreamnt
atgtttttgttgttctttttgcagggattcgataaacaagtggatgtgtcatatattgcc
aaacattacaacatgagcaaaagcaaagttgacaaccaattctatagtgtggaagtcgga
gactcaaccttcacagttctcaagcgctaccagaatttgaagcctattggctctggggct
cagggaatagtttgtgctgcgtatgatgctgttcttgacagaaatgtggccattaagaag
ctcagcagaccctttcagaaccaaacgcatgccaagagagcttaccgggagctggtcctc
atgaagtgtgtgaaccataaaaacattattagtttattaaatgtcttcacaccccagaaa
acattggaggaattccaagatgtttacttagtaatggaactgatggatgccaacttgtgt
caggtgattcagatggaattagaccatgaacgaatgtcttacctgctataccaaatgttg
tgtggcatcaagcaccttcactctgctggaattattcacagggatttaaaaccaagtaac
attgtagtcaagtctgattgtacattgaaaatcctcgactttggactagccaggacggca
ggcacaagcttcatgatgactccttatgtggttacacgttattatagagcccccgaggtt
attctgggaatgggctacaaggagaatgtggatatatggtctgtgggatgcattatggga
gaaatggttcgccacaaaatcctctttccaggaagggactatattgaccagtggaacaaa
gtaattgagcaactaggaacaccatgtccggaattcatgaagaaattgcaacctacagta
agaaactatgtggagaatcggcccaagtatgcaggactcaccttccccaagctctttcca
gattccctcttcccagcggactctgagcacaataaactcaaaggtatgcccatcagggac
aatttcagaaccactgtgcgggtgatggactaa

DBGET integrated database retrieval system