Mirounga leonina (Southern elephant seal): 118010522
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Entry
118010522 CDS
T07472
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01521
EGFR tyrosine kinase inhibitor resistance
mlx04010
MAPK signaling pathway
mlx04014
Ras signaling pathway
mlx04015
Rap1 signaling pathway
mlx04020
Calcium signaling pathway
mlx04072
Phospholipase D signaling pathway
mlx04144
Endocytosis
mlx04151
PI3K-Akt signaling pathway
mlx04510
Focal adhesion
mlx04540
Gap junction
mlx04630
JAK-STAT signaling pathway
mlx04810
Regulation of actin cytoskeleton
mlx05163
Human cytomegalovirus infection
mlx05200
Pathways in cancer
mlx05206
MicroRNAs in cancer
mlx05214
Glioma
mlx05215
Prostate cancer
mlx05218
Melanoma
mlx05230
Central carbon metabolism in cancer
mlx05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118010522 (PDGFRA)
04014 Ras signaling pathway
118010522 (PDGFRA)
04015 Rap1 signaling pathway
118010522 (PDGFRA)
04630 JAK-STAT signaling pathway
118010522 (PDGFRA)
04020 Calcium signaling pathway
118010522 (PDGFRA)
04072 Phospholipase D signaling pathway
118010522 (PDGFRA)
04151 PI3K-Akt signaling pathway
118010522 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
118010522 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
118010522 (PDGFRA)
04540 Gap junction
118010522 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118010522 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118010522 (PDGFRA)
05206 MicroRNAs in cancer
118010522 (PDGFRA)
05230 Central carbon metabolism in cancer
118010522 (PDGFRA)
05231 Choline metabolism in cancer
118010522 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
118010522 (PDGFRA)
05218 Melanoma
118010522 (PDGFRA)
05215 Prostate cancer
118010522 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
118010522 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118010522 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118010522 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mlx04090
]
118010522 (PDGFRA)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118010522 (PDGFRA)
Protein kinases [BR:
mlx01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
118010522 (PDGFRA)
CD molecules [BR:
mlx04090
]
Proteins
118010522 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
118010522
NCBI-ProteinID:
XP_034860857
LinkDB
All DBs
Position
Unknown
AA seq
1090 aa
AA seq
DB search
MMGTSLLALLILGCLLTGPSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQY
PMSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTEETEIEGRHIYI
YVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSSDGVVHASYDSRQGFN
GTFSVGPYVCEATIRGKTFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFN
NEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEV
KEMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIEN
LTEITTDIERIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILD
LVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAVLANNISNIITEVHPR
DRSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVI
ISLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKEELDIFGLNPSDDSTRS
YVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVK
NLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGM
MVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVEHLLPGQYK
KSYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYI
IPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGID
SSDLVEDSFL
NT seq
3273 nt
NT seq
+upstream
nt +downstream
nt
atgatggggacttcccttctggccctcctgatcttaggctgtctcctcacagggcccagc
ctaatcctctgccagctttcattaccgtctatcctcccaaacgaaaatgaaaaggtcgtg
cagctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtac
cccatgtctgaagaagagaaccccaatgtggaaatcagaaatgaggagaataacagtggc
ctttttgtgaccgtgctggaggtggtcaacgcgtcggcggcgcacacgggcttgtacact
tgctattacaaccacactcagacggaggaaacggagatcgaaggcaggcacatctacatc
tacgtgccagacccggatgtagcctttgtacctttaggaatgacagattatttagtcatc
gtggaggatgatgattctgccatcataccttgtcgcacaactgaccccgagactccggtg
accttgcgcagcagtgacggggtggtgcacgcctcctatgacagcagacagggctttaat
gggaccttcagcgtcgggccctatgtctgcgaagccaccatcagagggaagacgttccag
accatcccgtttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaa
gctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgtgccgtctttaac
aatgaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacc
atgctggaggaaatcaaggtcccgtccatcaaactggtgtacactctgagggtccccgag
gccacggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtc
aaagagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaaccc
aacttcagcccattggaagctgtcgacctacatgaagtcaaacattttgtggtggacgtg
caggcctacccacctcccaggatatcctggctgaaggacaacctgactctgattgaaaat
ctcacggagatcaccacggacatagaaaggattcaggaaataaggtatcggagcaaatta
aagctgatccgcgctaaggaggaagacagcggccattacacgatcgtcgttcaaaatgaa
gacgatgtgaagagctatactttcgagctcttaactcaagttccctcgtctattctggac
ttggttgatgaccaccatggctctacagggggacagactgtgagatgcaccgctgaaggg
acgcctcttcctgatatcgagtggatgatctgcaaggatattaagaagtgtaataatgaa
acttcatgggcggttttggccaacaatatctcaaacattatcacggaggtccacccccga
gacaggagtactgtggagggccgagtgacattcaccagggtggaggagaccatcgctgtt
cgatgtctggccaagaatctccttggggctgagagccgagagctgaagctggtggctccc
acgctgcgttctgaactcaccgtcgccgctgcggtcctcgtgctgttggtgattgtgatc
atctcacttattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgttgg
agggtcattgaatccatcagccctgacggacatgaatatatttacgtggacccgatgcag
ctgccttatgactcaagatgggagtttccaagggatggactcgtgcttggtcgtatcctg
ggatctggtgcgtttgggaaagtggttgaaggaactgcctatgggttaagccgctcccag
cctgtcatgaaagtagcagtgaagatgctaaaacccacagccagatccagtgagaaacaa
gctctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaac
ttgctgggagcctgcaccaagtcaggccctatttacatcatcaccgagtactgcttctat
ggggatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggag
aaaccaaaggaagagctggacattttcggattgaacccttccgatgacagcacacggagt
tatgttattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacacc
acccagtatgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagaga
tcgctgtatgaccgcccagcctcgtataagaagaagtctatgttagactcagaagtcaaa
aacctcctttcggacgataactcagaaggccttaccttgttggacttgttgagctttacc
tatcaagttgctcgaggaatggaatttttggcttcaaaaaattgtgtccaccgggacctg
gctgctcgaaacgtcctcctggcgcaggggaaaatcgtgaagatctgtgacttcggcctg
gccagagacatcatgcatgattcaaactacgtgtccaaaggcagtacctttctccccgtg
aagtggatggcccctgagagcatcttcgacaacctctacaccacgctgagtgacgtctgg
tcctacggcattctgctctgggagatcttttcccttggtggcacaccctaccccggcatg
atggtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgac
catgccaccagtgaagtctacgagatcatggtgaagtgctggcacagcgagccggagaag
agaccctccttctaccacctgagtgagattgtggagcatctgctgcctggacagtataag
aagagttatgagaagattcacctggacttcctgaagagcgaccacccggccgtggcgcgc
atgcgcgtggactcggacaacgcctacattggcgtcacctacaaaaacgaggaagacaag
ctgaaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatc
atccccctgcccgacatcgaccctgtccctgaggaggaggacctgggcaagaggaacaga
cacagctcgcagacctcagaagagagcgctatcgagacaggttccagcagctctactttc
atcaagagagaggatgaaaccattgaggacatcgacatgatggacgacattggcatagac
tcctcagacctggtagaggacagcttcctgtga
DBGET
integrated database retrieval system
