Mirounga leonina (Southern elephant seal): 118010767
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Entry
118010767 CDS
T07472
Symbol
HTT
Name
(RefSeq) huntingtin isoform X1
KO
K04533
huntingtin
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx05016
Huntington disease
mlx05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
118010767 (HTT)
05022 Pathways of neurodegeneration - multiple diseases
118010767 (HTT)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mlx03019
]
118010767 (HTT)
04131 Membrane trafficking [BR:
mlx04131
]
118010767 (HTT)
03029 Mitochondrial biogenesis [BR:
mlx03029
]
118010767 (HTT)
Messenger RNA biogenesis [BR:
mlx03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
118010767 (HTT)
Membrane trafficking [BR:
mlx04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
118010767 (HTT)
Mitochondrial biogenesis [BR:
mlx03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
118010767 (HTT)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_2
HEAT_EF3_N
Motif
Other DBs
NCBI-GeneID:
118010767
NCBI-ProteinID:
XP_034861294
LinkDB
All DBs
Position
Unknown
AA seq
3129 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQQQPPPPPQPPQALPQAQPPLPQPQPPQPPPPPPPPG
PAVAEEPLPRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSD
DAESDVRMVADECLNRVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLV
RPQKCRPYLVNLLPCLTRISKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIA
NLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEGEHSTLLILGVLLT
LRYLVPLLQQQVEDTSLKGSFGVTRKELEVSPSTEQLIQVYELTLQYTQHRDHNAVTGAL
ELLQQLLRTPPPELLQALSTPGGGPFAATHRQPGCRSRSGSIVELLAGGGSSCSPVLSRK
QKGKVLFGEAAALEDDSESRSEGSSPAFTASVKGELGGELAASSGVSTPGSASSATDSVG
HDIITEQPRSQHTLQPDSVDLTGCDLASAATDGDEEDILSHSSSQISAVPSDPAMDLNDG
TQASSPVSDSSQTTTEGPDSAVTPSDSSEIVLDGADSQYSGMQIGQPQDEDEEATGILPD
EDVDAFRSSSVALQQAHLLKSMGHSRQPSDSSIDKLVSRDEAAEPGDQENKPCRIKGDIG
QSTDDDSVPLVHCVRLLSASFLLTGEKNVLVPDRDVRVSVKALALSCVGAAVALHPESFF
SKLYKVPLDTMEYPEEQYVSDILNYIDHGDPQVRGATAVLCGTLISSILSRSRFQVGDWM
STIRALTGNTFSLVDCIPLLQKTLKDESSVTCKLACTAARHCVMSLCSSSYSELGLQLIT
DMLTLRDSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKLQERVLHDV
VIYLLGDEDPRVRHVAAAALMRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQP
PSHFSVSTITRIYRGYNLLPSMTDITVENNLSRVIAAVSRELVTSTTRALTFGCCEALCL
LSTTFPVCIWSLGWHCGVPPLNTSDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALV
LAGNLLAASAPKSLRSSWTSEEEANPTAAKQEEVWPALGDRTLVPMVEQLFSHLLKVINI
CAHVLDDVAPGPAMKAALPSLTNPPSLSPIRRKGKEKEPGEPASVPLSPKKGSEASPASR
QSDAPGPVTANKSSSLGSFCHLPSYLKLHDVLKATHANYKVTLDLQNSAEKFGGFLRSAL
DVLSQILELATLQDIGKCVEEILGYLKSCFSREPVMATVCVQQLLKTLFGTNLASQFDGL
SSNPSKSQGRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQDHDTSGWF
DVLQKVSTQLKTNLTSATKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQRQVLDL
LAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHS
KQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVV
VSMLLRLIQYHQVLEMFILVLQQCHKENEDKWKRLSRQIADVILPMLAKQQMHIDSHEAL
GVLNTLFEILAPSSLRPVDMLLRSMFVTPDTMASVSTVQLWISGILAILRVLISQSTEDI
VLSRIQELSFSPYLISCPIIDRLRDGDSTSTPEEHNEGRQIKSLPEETFSRFLLQLVGIL
LEDIVTKQLKVEMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAASRLFAADHADGT
FYDLERLNARVRTMLPTHPALVLLWCQILLLVSHTDYRWWAEVQQTPRRRSLSSTKSLSP
QMPGEEEDPDAACKLGVCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLINLS
HEPPVQDFISAVHRNSAASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQSGAVLIL
YVDKLLCTPFRVLARMVDTLACRRVEMLLAANLQSSTAQLPVEELSRIQEYLQSSGLAHR
HQRLYSLLDRLRLATAPGSRGPSPPVTSHPLDGDGPLALETMIPDKDWYLRLVKSQCWTR
SDSALLEGAELVNRIPPSDMSTFMMNSEFNLSLLAPCLGLGMREISGGQRSPLFEAARLA
TLDRVSGLVQQLPATHHVFQPFLPVEPTAYWNKLNDLFGDAVLYRSLTTLARALAQYLLV
FSKLPSHLHLPPEKERDTVKFVVMTLEALAWHLIHEQIPLSLDLQAGLDCCCLALQLPSL
WSVLSSPEMVTHACSLIHCVRFVLEAVVVQPGDQLLSPERRMNTTKASREDEVDSNTQNP
AYITAACGMVAEMVESLPSVLALGHKRNSNTPAFLTLVLRNIIVSLARLPLVNSYTRVPP
LVWKLGWSPKPGGDFGTCFPEIPVEFLQEKEVFKEFIYRINALGWTSRTQFEETWATLLG
VLVTQPLVMEQEESPPEEDTERTQINVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPRN
KPLKALDTRFGRKLSIIRGIVEQEIQAMVSKRENIATHHLYQAWDPVPSLSPATTGALIS
HDKLLLQINPERELGNMSYKLGQVSIHSVWLGNSITPLREEEWEEEEEEEADVPAPASPP
TSPVNSRKHRAGVDIHSCSQFLLELYSRWILPSGSARRTPIILISEVVRSLLVVSDLFTE
RTQFEMMYLTLTELRRVHPAEDEILIQYLVPATCKAAAVLGMDKAVAEPVSRLLESTLRS
SHLPSKVGALHGALYVLECDLLDETAKQLVPVISDYLLSNLKGVAHCVNIHSQQHVLVMC
ATAFYLIENYPLDVGPEFSASIIQMCGVMLSGSEEATPSIIYHCVLRGLERLLLCEQLCR
LDAESLVKLSVDRVNVHSPHRAMAALGLMLTCMYTGKEKISPGRTSDPSPGAPDSESVIV
AMERVSVLFDRVRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMA
TVVYKVFQTLHTTGQSSMVRDWVMLSLSNFTQRTPVAMAVWSLSCFFISASTSPWVSAVL
PHVISRMGKLEQVDVNLFCLVATDFYRHQIEEELDRRAFQSVFEVVAAPGNPYHRLLTCL
RNVHKVATC
NT seq
9390 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccctcgagaagctgatgaaggccttcgaatccctcaagtcctttcagcagcag
cagcagcagcagcagcagcctccgccgccgcctcagcctcctcaggcgctgccgcaggcg
cagccgccgctgcctcagccgcagccgccgcagccgccgccgccgccgccgccccccggc
ccggccgtggccgaggagccactgccccgaccaaagaaggaactctcagccaccaagaaa
gaccgcgtgaaccattgtctgacaatatgtgaaaacatcgtggcacagtcactcagaaat
tctccagaatttcagaaacttctgggcatcgctatggaactttttctgctgtgcagtgat
gatgcagagtcggatgtccggatggtggctgacgagtgcctcaacagagtcataaaagcc
ctgatggactccaatcttccgaggctacagttagaactctataaggaaatcaaaaagaac
ggtgctccccggagcctgcgcgccgccttgtggaggtttgctgaactggctcacctggtc
cggcctcagaagtgcaggccttacttggtaaaccttttgccttgcctgactcgaataagc
aagagacctgaggaatctgttcaggagaccttggctgcagctgtacccaaaattatggct
tcttttggcaattttgcaaatgacaatgaaattaaggttctcttaaaggctttcatagcg
aatctgaagtcaagctccccgaccattcggcggacggcggctggctcagcggtgagcatc
tgccagcactcgagaaggacgcagtatttttatagctggctactaaatgtgctcttaggt
ttgctggtccctgttgagggtgaacattctaccctcctgattcttggagtgctgctcaca
ctgagatacctggtgcccttgttgcagcagcaggtcgaggacacgagcctgaaaggcagc
tttggggtgacacggaaagaactggaagtctccccgtcgacagagcagcttatccaggtc
tacgagctgaccctgcagtacactcaacaccgagaccacaacgccgtgaccggagcgctg
gaactcctgcagcagttgctcaggacgccgccgcccgagctcctgcaggccctgagcacg
ccgggcggcgggccattcgccgccacccaccgccagcccggctgccggagccgcagcggc
agcatcgtggagctgctagctggagggggttcttcatgcagccctgtcctttcaagaaaa
caaaaagggaaagtactcttcggagaagcagcggccttggaggatgactccgagtccagg
tcggagggcagcagccccgccttcacagcctcagtcaagggtgagcttggtggcgagctg
gctgcctcttccggggtctccactcctggctctgccagttcagccaccgactccgtgggc
cacgacatcatcactgagcagccccggtcacagcacacgctacagccagactcggtggat
ctgaccggctgtgacctggcgagcgctgccaccgacggggatgaggaggacatcctgagc
cacagctccagccagatcagtgccgtcccgtctgacccggccatggacctgaacgatggc
acccaggcctcctccccagtcagcgacagctcccagaccaccactgaggggcctgattca
gctgtgaccccttcagacagttctgaaattgtgttagatggtgccgacagccagtattcg
gggatgcagatcggacagccacaggacgaggatgaggaagccacgggcattcttccggat
gaagacgtagatgctttcagaagctcttcagttgccctgcagcaagcacatttattgaaa
agtatgggccacagcaggcagccctctgacagcagtatagataaacttgtctccagagat
gaagctgccgaaccgggagatcaagaaaacaagccttgccggatcaaaggtgacatagga
cagtctactgatgacgattctgttcctcttgtccattgtgtccgccttctatctgcttca
tttttgctgactggggaaaaaaatgtgctggttccggacagggacgtgagggtcagtgtg
aaggcgctggcactcagctgtgtgggggccgctgtggcccttcatcctgagtctttcttc
agcaaactttataaagtacctcttgacaccatggagtaccctgaggagcagtatgtgtca
gacatcctgaactacatcgatcatggagacccccaggtcagaggagccacggccgttctc
tgtgggaccctcatctcctccatcctcagcaggtcccgcttccaagtgggagactggatg
agcaccatcagggccctgacaggaaatacattttctctggtggactgcattcctttgctg
cagaaaactttgaaggatgaatcttctgtgacttgcaagttggcttgtacagctgcgagg
cactgtgtcatgagtctctgcagcagtagttatagcgaattgggattacagctgatcacc
gacatgctgaccttgagggatagttcctactggctggtgaggacagagcttttggaaact
cttgcagagattgactttaggttggtgagctttttggaggcaaaagcagaaaacctgcac
agaggggcgcatcattacacagggcttttaaaactgcaagaacgagtgctgcatgatgtc
gtcatctatctgctcggggacgaggaccccagggtgcggcacgttgccgcagcagctttg
atgaggcttgtcccaaagctgttctacaagtgcgaccaaggacaagctgaccctgtcgtg
gctgtggcgagagatcaaagcagtgtttacctgaagctcctcatgcacgagacgcagcct
ccatctcacttctccgtcagcaccatcaccagaatatacagaggctataacttactgccg
agcatgacggacatcactgtggaaaacaacctctccagagtcatcgcggcagtttcccgt
gaactggtcacgtccaccacgcgcgcactcacatttggatgctgcgaagctctgtgtctc
ctttcaaccacctttcccgtctgcatttggagtttaggttggcattgtggggtgccccca
ctgaacacctctgatgaatcgagaaagagctgtactgttggcatggccacaatgatcctc
accttgctctcatcagcttggttcccgctggatctctcagcccatcaggatgctttggtt
ttagccggaaacttgcttgcagccagtgcccccaaatctctgagaagttcctggacctcc
gaagaagaggccaacccaacagctgccaagcaggaagaggtctggccagctctgggtgac
cggaccctggtgcccatggtggaacagctcttctcccacctgctgaaggtgattaatatc
tgtgctcacgtcttggacgatgtggctccgggaccagcaatgaaggcagccttgccatct
ctgacaaaccctccttctctaagtcccatccgacgaaagggaaaggagaaagaacccgga
gagccggcctctgtgcccttgagccccaagaaaggcagtgaagccagtccagcctctcga
caatctgatgccccagggcctgttacagcaaataagtcctcgtcgctggggagtttctgt
caccttccttcgtacctcaaattgcatgacgtcctgaaagctactcacgccaactacaag
gttaccttggatcttcagaacagcgctgaaaagtttgggggctttctgcgctctgccttg
gatgtcctctctcagatcctagagctggcgacgctgcaggacatcgggaagtgtgttgag
gagatcctagggtatctgaaatcctgtttcagtcgggaaccagtgatggcaactgtttgc
gttcagcagctgttgaagactctctttgggacaaacctggcctcccagtttgatggctta
tcctccaaccccagcaagtctcaaggccgagcacagcgtctgggctcctccagtgtgagg
ccaggcttgtaccactactgcttcatggctccgtacacccacttcacccaggccttagcc
gacgccagcctgaggaacatggtgcaggcggagcaggaccacgacacttcagggtggttt
gacgtgcttcagaaggtgtctacccagttgaagaccaacctcacgagcgccacaaagaac
cgcgcggataagaatgctattcataatcacattcgcttgttcgagcctctggttattaaa
gctttgaaacagtacacaaccaccacgtccgtgcagctgcagaggcaggtcctggacctg
ctggcccagctggtgcagttacgggtcaattactgtcttctggactcggaccaggtgttt
attggatttgtgctgaagcagtttgaatacattgaagtaggccagttcagggaatcagag
gcaattattccaaacatctttttcttcctggtattactatcttacgaacgctatcattca
aaacagatcattggaattcctaaaatcattcagctctgtgatggcatcatggccagtggg
aggaaggctgtgacacatgccataccagctctgcagccgatagtccacgacctctttgtc
ctgagaggaaccaataaagccgacgcaggaaaagagcttgaaacccagaaagaggtggtg
gtgtcgatgctgctgagactcatccagtaccatcaggtgttggagatgttcatcctggtc
ctgcagcagtgccacaaggagaacgaagacaagtggaagcgactgtctcggcagatagcc
gacgtcatcctcccgatgttagccaagcagcagatgcacattgattctcatgaagccctt
ggagtgttaaatactttatttgagattctggccccttcctccctccgtcccgtggacatg
cttttacggagtatgtttgtcactccagatacaatggcatctgtgagcactgttcaactg
tggatctcaggaatcctggccattttgagggttctcatttcccagtcaactgaagatatt
gttctttctcgtattcaggagctctccttctccccatatttaatctcctgtccaataatt
gataggttaagagatggggacagtacttcaacaccggaagaacacaacgaagggagacaa
atcaagagtttgccagaggaaacattttcaaggtttctactacaactagttggcattctt
ttggaggatattgttacaaaacagctaaaagtggaaatgagtgaacagcaacatactttc
tattgtcaagaactaggcacgctgctaatgtgtctgatccatatcttcaagtctggaatg
ttccggagaatcacggcggctgcctcgagactcttcgcggcggaccacgccgacggcact
ttctacgacctggagaggctgaatgcgcgcgtgcgcaccatgctgcccacgcacccagcg
ctcgtgctgctctggtgccagatcctgctgctcgtcagccacaccgactaccgctggtgg
gcagaggtgcagcagacccccaggagacgcagtctgtccagtacgaagtcactcagcccc
cagatgcctggagaggaggaggaccccgatgcagcctgcaagcttggggtgtgcaataga
gaaatagtgcgaaggggagcactcattctcttctgcgattatgtctgtcagaacctacac
gattcagagcacctaacatggctcattgtgaatcacatccaggacctgatcaatctatcc
cacgagccccccgtgcaggattttatcagtgctgttcatcggaactccgctgccagtggc
ctcttcatccaggcgattcagtctcgttgtgaaaacctttcaacccctaccaccctgaag
aagacgcttcagtgcttagaagggatccacctcagccagtcgggcgctgtgttaatactg
tatgtggacaagcttttgtgtactccgttccgtgtgctggctcgcatggtcgacactcta
gcctgtcgccgggtggaaatgcttctggctgcaaatttacagagcagcacggcccagctg
ccagtggaggagctcagcaggatccaggaataccttcagagcagcggcctggctcacaga
caccagaggctctactccctgctggacaggcttcgtctcgccactgcacccggctcacgt
ggcccttctcctccggtcacgtcccacccgctggacggggatgggcccctggcactggag
accatgattccagacaaagactggtacctacgtctagtcaaatcccagtgctggactagg
tcagattctgcgctgctggaaggggcagaactggtgaatcggattcctcccagtgacatg
agtacattcatgatgaactcggaattcaacttaagcctgttggccccgtgcctgggcctg
ggcatgcgcgaaatctccggaggccagaggagtcccctcttcgaagcagctcgcctggcc
actctggaccgtgtgagcggcctggttcagcagctccctgccacccaccacgttttccag
ccgttcttgcctgtggagcccaccgcctactggaacaagttgaatgatctatttggggat
gctgtattgtatcggtccttgaccactctggcccgggccctggcccagtacctgcttgtg
ttctccaagctgcccagccatttgcacctccctcctgagaaggagagggacactgtgaaa
tttgtggtcatgactctcgaggccctggcgtggcatttgatccatgagcagatcccactg
agtctggacctacaggccggcctagactgctgttgcctggccctgcagctgcccagcctc
tggagcgtgctatcctccccagagatggtcacccatgcctgctctctcattcactgtgtc
cgcttcgtcttggaagccgttgtggtgcagcctggggatcagcttcttagtccagaaaga
aggatgaacaccacaaaggcttccagagaggatgaagtagattcaaacacacaaaacccg
gcatatatcaccgcagcctgtgggatggtggcagaaatggtggagtctttgccgtcggtg
ttggccttggggcataaaaggaatagcaacaccccagcgtttctcacgttggtgctcagg
aacatcatcgtcagcctggctcgcttacccctcgtcaacagctatacgcgcgtcccccca
ctggtttggaagctcggatggtcgcccaagccgggaggtgactttggcacatgcttccct
gagatcccggtggagttcctccaggagaaggaagtctttaaagagttcatctaccgcatc
aatgcactagggtggaccagccgcacccagtttgaggaaacgtgggccaccctccttggc
gtcctggtgactcagcccctcgtgatggagcaggaggagagcccgccggaagaagacacg
gagcggacccagatcaatgtcctggccgtgcaggccatcacctccctggtgctgagcgcc
atgaccgtgcccgtggccggcaacccagccgtgagctgcttggaacagcagccccggaac
aagcccctcaaagccctcgacaccaggtttgggaggaagctgagcattatccgaggaatt
gtagagcaggaaatccaagcgatggtttcaaagagagagaacatcgccacgcatcactta
taccaggcgtgggaccccgtcccttctctgtctccagctacgacaggtgccctcatcagc
catgacaagcttctgctgcagatcaaccccgagcgggagctggggaacatgagctataag
ctcggccaggtgtccattcactccgtgtggctggggaacagcatcacacccctgagagag
gaggagtgggaggaagaggaggaggaggaggccgatgttcccgcccctgcgtctccaccc
acatcacccgtcaactccaggaagcaccgggctggggtcgatatccactcctgttcccag
tttttgctcgaactgtacagtcgctggatcctaccgtcagggtcagcccgaaggacgccc
atcatcctgatcagtgaagtggttcgatctctcctagtggtctcagacttgttcactgaa
cgcacccagtttgagatgatgtatctgacgctgacagagctgcggagggtgcaccctgca
gaagatgagattcttattcagtacctggtacccgccacctgcaaggcggctgccgtcctg
ggaatggataaggctgtggcagagcccgtcagccggctgctggagagtaccctgaggagc
agccacctgcccagcaaggtcggggccctgcacggcgctctctacgtgctggagtgtgac
ctcctggatgagacggccaaacagctcgtcccagtcatcagcgactacctcctgtccaac
ctcaaaggggtggcccactgcgtgaacattcatagccagcagcatgtgctggtgatgtgt
gccaccgccttctacctgatcgagaactatcccctggatgtgggcccggagttctctgcg
tcaatcatacagatgtgtggggtgatgctgtccggaagtgaggaagccaccccgtccatc
atctaccactgcgtcctgcggggcctggagcgcctcctgctgtgcgaacagctgtgccgc
ctggatgcggagtccctggtcaagctgagtgtggacagagtgaatgtgcacagcccacac
cgggccatggccgccctgggcctgatgctcacctgcatgtacacagggaaggagaaaatc
agtccgggcagaacctcagaccccagccccggcgccccagacagtgagtcagtgattgtg
gctatggaacgcgtgtctgttctttttgacagggtcaggaaagggttcccctgtgaagcc
agagtggtggcacggatccttcctcagtttttagacgacttcttcccaccccaggatgtc
atgaacaaagtcattggagaatttctctccaaccagcagccataccctcagttcatggcc
accgttgtgtacaaggttttccagacgctgcacaccaccgggcagtcatccatggtccgg
gactgggtcatgctgtccctctccaacttcacccagaggaccccggtggcaatggccgtg
tggagcctctcctgcttcttcatcagcgcttccaccagcccgtgggtctcggctgtcctt
ccccacgtcatcagcaggatgggcaagctggagcaggtggacgtgaacctcttctgcctg
gtggccacggacttttacagacaccagatagaagaggagctggaccgccgggccttccag
tccgtgttcgaggtggtcgcggcaccaggaaacccatatcatcgattgctgacttgtttg
cggaacgtccacaaggtcgccacatgctga
DBGET
integrated database retrieval system
