Mirounga leonina (Southern elephant seal): 118012075
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Entry
118012075 CDS
T07472
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00230
Purine metabolism
mlx00670
One carbon pool by folate
mlx01100
Metabolic pathways
mlx01523
Antifolate resistance
Module
mlx_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
118012075 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
118012075 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118012075 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlx04147
]
118012075 (ATIC)
Enzymes [BR:
mlx01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
118012075 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
118012075 (ATIC)
Exosome [BR:
mlx04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118012075 (ATIC)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
118012075
NCBI-ProteinID:
XP_034863108
LinkDB
All DBs
Position
Unknown
AA seq
592 aa
AA seq
DB search
MAPSQLALFSVSDKTGLVDFARNLTSVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEM
LGGRVKTLHPAVHAGILARNIPEDSADMARLDFSFIRVVVCNLYPFVKTVASPDVTVEQA
VEQIDIGGVTLLRAAAKNHVRVTVICDPEDYVAVSTELQSSDSKDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELREALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPIS
TAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIVAPGYEDEALKILCKKKNG
SYCVLQMDQSYNPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKDLPEFALRDLIV
ATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPDLLTEEEKKKWVDKLSEVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggcacccagccagctcgccttatttagtgtctctgacaagacgggccttgtggatttt
gccagaaacctaacttctgttggtttgaatctgatcgcctccggagggactgcaaaagct
ctcagggatgcgggtctggcggtcagagatgtctctgagctgacgggatttcctgaaatg
ttagggggacgtgtgaaaaccttgcatcctgcagtccatgctggaatcttggctcgtaat
atcccagaagatagtgctgacatggccagacttgatttcagttttataagggttgttgtc
tgtaatctgtatccctttgtgaagacagtggcttctcctgatgtaactgttgaacaggct
gttgagcagattgatattggtggagtaaccctactgagagcagcagccaaaaaccacgtt
cgagtgacagtcatatgtgaccccgaggactatgtggccgtgtccacagagctgcaaagc
tctgacagcaaagacacctccttggagactagacgccagttagccttgaaggctttcact
catacggcacaatatgatgaagctatttcagattacttcaggagacagtatagtaaagga
atatctcagatgcctttgaggtatggaatgaaccctcatcaaactcctgcccagttatac
acactgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttg
tgtgatgctttgaatgcctggcagctggtgaaggaactcagagaagctttaggcattcca
gccgctgcctctttcaaacatgtcagcccagcaggtgctgctgttggaattccactcagt
gaagatgaggccaaagtctgcatggtctatgatctgtataaaacccttacacccatatca
actgcgtatgcaagagcaagaggggccgataggatgtcttcctttggtgattttgttgca
ttatctgatgtttgtgatgtccctactgccaaaattatctccagagaggtatctgatggt
attgttgccccaggatatgaagatgaagctttgaaaatactttgtaaaaagaaaaatggg
agttactgtgttcttcagatggatcagtcctacaatccagatgaaaacgaagttcgaact
ctctttggtcttcgtttaagtcagaagagaaataatggtgtcattgacaggtcattattt
agcaacgttgtgaccaagaataaagatttgccagagtttgcgctcagagacctcattgtg
gccaccattgctgtgaagtacacgcagtctaactccgtgtgctatgccaagaatggtcag
gttattggcattggagcgggacagcagtctcgaatacactgcacacgtcttgcaggagat
aaagcaaactattggtggcttagacatcatccacaggtgctttcaatgaagtttaaaact
ggagtgaagagagcagaaatctccaatgccattgatcagtatgttactggaaccattggc
gaggatgaagatttgataaagtggaaggcgttgtttgaggaagtgcctgatttactaact
gaagaagagaagaagaaatgggttgacaaacttagtgaagtttctgtcagctctgatgcc
ttttttcctttcagggataatgtagacagagctaaaaggagtggtgtggcctatattgct
gctccttctggttctgctgctgacaaagttgtgattgaggcttgcgatgaactgggaata
atccttgctcatacgaatcttcggctctttcatcactga
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