Mirounga leonina (Southern elephant seal): 118013325
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Entry
118013325 CDS
T07472
Symbol
ARHGEF12
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04270
Vascular smooth muscle contraction
mlx04360
Axon guidance
mlx04611
Platelet activation
mlx04625
C-type lectin receptor signaling pathway
mlx04810
Regulation of actin cytoskeleton
mlx05135
Yersinia infection
mlx05152
Tuberculosis
mlx05163
Human cytomegalovirus infection
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
118013325 (ARHGEF12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
118013325 (ARHGEF12)
04625 C-type lectin receptor signaling pathway
118013325 (ARHGEF12)
09153 Circulatory system
04270 Vascular smooth muscle contraction
118013325 (ARHGEF12)
09158 Development and regeneration
04360 Axon guidance
118013325 (ARHGEF12)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118013325 (ARHGEF12)
05205 Proteoglycans in cancer
118013325 (ARHGEF12)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
118013325 (ARHGEF12)
09171 Infectious disease: bacterial
05135 Yersinia infection
118013325 (ARHGEF12)
05152 Tuberculosis
118013325 (ARHGEF12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118013325 (ARHGEF12)
Membrane trafficking [BR:
mlx04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
118013325 (ARHGEF12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RGS-like
PH_16
RhoGEF
PDZ
PDZ_6
PH_13
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
Ribonuc_2-5A
AAA_23
Motif
Other DBs
NCBI-GeneID:
118013325
NCBI-ProteinID:
XP_034865038
LinkDB
All DBs
Position
Unknown
AA seq
1549 aa
AA seq
DB search
MELVDPLPRGLTHMLGRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSKKT
KSSSEESRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRI
IKVNGTLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLAESEVEPSVIGHMSPIMT
SPHSPGASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQR
LLKEIQEAKKHIPELQEQLSKATGSAQDGAVVTSSKPLGDPLTVSEVEADPGDGLGRIDS
SSGDASRPSSDSADSPKSAVKERIYLEENPEKSEVTQDTDTQSLIGSPSPRIAPHIIGAE
DDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTN
SKETRRVFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIQTMQERVHP
EVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRVTLEKERACAEQIIAKIEEVLMTAQ
AVEEDKSSTMQYVILMYMKHLGVKVKEPRSLEHKRGRIGFLPKIKQSMKKDREGEEKGKR
RGFPSILGPPRRPSRHDNSAIGRAMELQKQRHPKHLPAPSSVSPEPQDPAKVRQSGSAGE
GTDVGYLPANSMSSVASGAAPSQEGGKENDTGSKPVGETPASGDCIDSTPRTPNTVFDFP
PPPLDQVQEEEWEVERVTEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVS
REVLLGLKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSN
LEDILQLHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEDKLKHAAATFCSNQPFA
LEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWP
MEREKVKKAADHCRQILNYVNQAVKEAENKQHLEDYQRRLDTSNLKLSEYPNVEELRNLD
LTKRKMIHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKH
TFSPVIKLNTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASV
KEQSAKPIPLPQSPPCEGDNDEEAAPKLKVEHHSISVPGLQSPDRDLGLESPLISSKPQS
HSLGTSGKSEVDDLFVAERQFAKEQHADGTLQEAGASYQITTPDPHLPASEERWALDALR
NLGLLKQLLVQQLGLTEKSAQEDWPHFPSYRTASSGVQTDGGAQNSENSKAYPPVEGQMP
FSTGTGDIAPCHSPRTSTESPASRDSVVLAFQDSQASTIFVMDHMLMTPEMPPAEPEGSL
DESGEHFFDAREAHSDDNPSEGDGAVKKEEDVNLRISGNYLILDGYEAVQESSTDEEVAS
SLPPPPATGIPSMDSAPLQHHSPRRAHSDGAASPFTPEFLVQQRWGAMDDSCFEIQSPPS
CADSQSQIMEYIRKIEADLEHLKKVEESYSMLCQRLAGSALTDKHSDKS
NT seq
4650 nt
NT seq
+upstream
nt +downstream
nt
atggagctggtggatccacttccaaggggactcactcacatgctgggcaggtttcccctc
aaaaaacctataaggcatgggagtattttgaaccgagagtcaccaacagataagaagcag
aaagttgagcgcagtgcatcacatgattttgatcctacagatagctcctccaagaagaca
aagtctagttcagaggagagtagatccgagatatatggtcttgttcagcgttgtgtgatc
atccagaaggatgacaatggatttgggctgacggtcagtggagacaatccagtcttcgta
cagtctgtcaaagaagatggagcagccatgcgggctggggtacagacaggtgatcgaatc
atcaaggtgaatggaactctggtgactcattcaaaccatttggaagtggtgaagctaatc
aaatctggttcctatgtagctctcactgtgcagggacgcccacctgggtcgccccagatt
ccactcgccgaatctgaagtagagccatcagtcattggacatatgtctcccatcatgaca
tcccctcattcacctggagcatctgggaacatggagagaattactagtcctgtgctcatg
ggggaggaaaacaatgtggttcataaccagaaagtagaaattctgagaaaaatgttacag
aaagagcaggaacggctgcagttattgcaggaagattacaaccgaacacctgcccaaaga
ttgctaaaagagatccaagaggccaagaaacacattcctgagctgcaagagcagctatcc
aaagccacaggctctgctcaggatggagctgttgttacatcctccaagcctttaggtgac
cccctgacagtcagtgaggtggaagccgatcctggtgacgggctaggcagaattgactct
agcagtggagatgcttctcggcccagtagtgacagcgcagacagtcccaagagtgccgtg
aaagagaggatttatctagaggaaaacccagagaaaagtgaagtgactcaggacactgat
actcagtcactcatcgggagtccctctccccgtatagcacctcatattattggagcagag
gatgatgatttcggtactgaacatgaacagatcaatgggcagtgcagctgtttccagagc
atcgaactgctgaaatctcgccctgctcacctggctgttttcttacaccacgtggtctca
cagtttgaccccgcgacgctgctttgttatctctattcagacctgtataagcagaccaat
tccaaggagactcgtcgtgtcttccttgagtttcatcagttcttcctggatcgatctgca
cacctgaaagtttctgtgcctgatgaaatatcagtagatctagaaaaaagaagacctgag
cttatacccgaggatctgcaccgccactatatccaaactatgcaggaaagagtccaccca
gaagttcagaggcacttggaagattttcggcagaagcgtagcatggggctgaccttggct
gaaagcgaactgactaaactcgatgcagagcgagacaaggaccgggtaactttggagaag
gaacgggcatgtgcggaacagatcattgccaaaattgaagaagtgttgatgactgctcag
gctgtagaagaagataagagctcaacaatgcagtatgttatccttatgtacatgaagcac
ttgggggtaaaagtgaaagaacctcgaagtttggagcacaagcggggtcggattggattc
ctcccaaagatcaagcagagtatgaagaaagatcgagaaggcgaagaaaaagggaagcgc
agaggattccccagcatcctgggacccccaaggagaccaagccgtcatgacaacagtgca
attggcagagccatggagctacagaaacagcgccacccaaagcacttacccgcaccctct
tctgtaagtcctgagcctcaggatcctgctaaggtgcgccagagtgggtcagcaggtgaa
ggaacagatgtcggatacctgccagccaattccatgtcctctgtggcatcaggagccgct
ccttcccaggaaggagggaaagagaatgatacaggatcaaagccagttggagaaacacca
gcatctggagactgcatagatagcacccctcggactcccaatactgtctttgatttccca
cctcctcccttagaccaagtgcaggaggaagagtgggaagtggaaagggtgactgaacat
gggacaccaaagccctttcgaaagtttgacagcatagcttttggagaaagtcaaagtgag
gatgaacagtttgaaaatgacttagagacagatccacccaactggcaacagctcgttagt
cgagaagtattactgggactaaagccttctgagatcaaaagacaggaagtaattaatgaa
ttattctacactgaaagagctcatgttcgaacactgaaggttcttgatcaagtattctat
cagcgagtgtccagagaaggaattctgtcaccttcagaactacggaaaattttttcaaac
ttggaagatattcttcaacttcatattggattgaatgagcaaatgaaggctgttcgaaag
aggaatgagacctcagttattgatcagattggagaagatttgctgacctggttcagtgga
ccaggggaggacaagttgaagcatgctgctgccaccttttgcagtaaccaaccctttgcc
ctggaaatgatcaagtctcgtcagaaaaaggattctcgattccagacctttgtgcaagat
gctgagagtaatcctctgtgtcgtcgtctgcagctgaaggatatcattcctacccaaatg
cagaggcttaccaagtaccctcttctgttggataatattgccaaatacacagaatggcca
atggaaagggagaaggtgaagaaagccgcagatcactgtcgtcagatcttaaattatgta
aatcaggctgtcaaggaggcagaaaacaaacagcatttagaagactatcagcgtcgtctg
gatacctccaatctgaagttgtcagagtacccaaacgtggaagagctcaggaatttggat
ttaacaaaaaggaagatgatccacgaagggccattggtctggaaggtgaatcgagataaa
actattgatctatacacattgctgctcgaagacattcttgtattgttacaaaagcaggat
gacagactggtgttaagatgtcatagtaagattctggcgtctaccgctgatagcaaacac
acatttagccctgtcattaagttgaatacagtgttggttcgacaagtggcaacagataac
aaagctttatttgtcatctccatgtcagacaatggagcccaaatttatgaactggtggca
cagactgtttccgaaaagaccgtctggcaagacctcatctgtcggatggctgcatccgtg
aaggaacagtccgcaaagccaatcccattgccacagtcaccaccttgcgaaggagacaac
gatgaagaagcagctccaaagttaaaagtggaacatcacagcatttcggtccctggtcta
cagagtccagacagagatttgggattagagtctcccttaatatcgtcaaaacctcagtct
cattcactcggtacctctgggaaatccgaggtagatgatctgtttgtggctgagagacag
tttgctaaggagcagcatgcagatgggactctgcaggaagctggagcaagttaccagatc
acaaccccagacccacacttgcctgcctcagaagaacggtgggcattggatgcactaagg
aatttgggcttgctgaagcagctgctcgtacaacagctgggtttgactgagaagagcgct
caggaagactggccacatttcccaagctacaggacagcgtcttcaggggtgcagacagac
ggtggggcccagaactcagagaacagtaaggcctatcctcctgtcgaaggacagatgccc
tttagtactggaactggtgacattgcaccttgtcacagtccacggacttcaactgaatct
ccggcttcacgggattcagtggtactggccttccaagatagccaggcaagtaccatcttc
gtcatggaccacatgcttatgaccccagagatgcctcctgcagagccagaagggagtctc
gatgagagtggagagcacttttttgatgcccgtgaagcacacagtgatgataatccatca
gaaggtgatggagcagttaagaaggaagaggatgttaatttgcgcatctcaggaaactat
ttgattctggatggctatgaagcggtgcaggagagctccacggatgaggaggttgcctcc
tcgcttcccccgccacccgcgacaggcatcccctccatggactctgcccccctgcagcat
cactcgccccggcgtgcccattctgatggggcagcttcaccgttcaccccagaattcctg
gtccagcagcgctggggagctatggatgattcctgttttgagatccagagtcccccttct
tgtgcagactcacagagccagatcatggagtacattcgtaagatcgaggctgaccttgaa
cacttaaagaaggtggaggaaagttacagcatgctttgccaaaggctggctggatcagcc
ctcacagacaagcactcagataaaagttag
DBGET
integrated database retrieval system
