Mirounga leonina (Southern elephant seal): 118013609
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Entry
118013609 CDS
T07472
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00010
Glycolysis / Gluconeogenesis
mlx00620
Pyruvate metabolism
mlx01100
Metabolic pathways
mlx01200
Carbon metabolism
mlx01230
Biosynthesis of amino acids
mlx04910
Insulin signaling pathway
mlx04930
Type II diabetes mellitus
mlx04932
Non-alcoholic fatty liver disease
mlx04950
Maturity onset diabetes of the young
Module
mlx_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mlx_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118013609 (PKLR)
00620 Pyruvate metabolism
118013609 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
118013609 (PKLR)
04950 Maturity onset diabetes of the young
118013609 (PKLR)
04932 Non-alcoholic fatty liver disease
118013609 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlx04147
]
118013609 (PKLR)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
118013609 (PKLR)
Exosome [BR:
mlx04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118013609 (PKLR)
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Paralog
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
118013609
NCBI-ProteinID:
XP_034865364
LinkDB
All DBs
Position
Unknown
AA seq
573 aa
AA seq
DB search
MSSQESIQAQELWSRISKSQRDLAKSFLIGAPGGPAGYLRRASAAQLTHELGTAFFQQQL
SAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASHSVESLKEMIKAGMNIARLNFSH
GSHEYHAQSIANIREAVESFATSPLGYRPVAIALDTKGPEIRTGVLRGGPEAEVELVKGS
LVLVTVDTAFRTLGDANTMWVDYPNIVKVVPVGSRIYIDDGLISLLVKKIGPEGLETQVE
NGGLLGSRKGVNLPGVEVDLPGLSEQDVLDLRFGVQHNVDIVFASFVRKASDVAAIRAAL
GPEGRDIKIISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCN
LAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGRFPVEAVKMQ
HAIAREAEAAVYHRQLFEELRRAASLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSA
QLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGIESGK
LRGFLRMGDLVIVVTGWRPGSGHTNIMRVLSIP
NT seq
1722 nt
NT seq
+upstream
nt +downstream
nt
atgtccagccaggagagcatacaagcccaggagctttggtcaaggatttctaagtcccaa
agggacttagcaaagtccttcctgattggggctccaggagggccggcgggctacctgcgg
cgggccagcgcggcccagctgacccacgagctgggcacggccttcttccagcagcagctg
tcggccgccatggcggacaccttccttgagcacctgtgcctgctggacatcgactcggag
cccgtggccgcccgcagcaccagcatcatcgccaccatcggaccggcctctcactcggtg
gagagcctcaaggagatgatcaaggccgggatgaacatcgcgcgcctcaacttctcgcac
ggctcccacgagtatcacgctcagtccatcgccaacattcgggaggcggtggagagcttt
gcaacttctccgctcggctaccgacccgtggccatcgccctggacaccaagggaccggag
atacgcaccggggtcctgcgggggggcccggaggccgaggtggagctggtgaagggctcc
ctggtgctggtgaccgtggacacggcgttccggactctgggggacgcgaacaccatgtgg
gtggactaccccaatatcgtcaaggtcgtgccggtggggagccgcatctacatagacgac
ggcctcatctccctcctggtcaagaaaatcggcccagaggggctggagacccaagtggag
aacggaggcctcctgggcagccggaagggcgtgaacttgccaggtgttgaggtggacttg
cccgggctgtctgagcaagacgtcctggacctgcgcttcggggtgcagcacaacgtggac
atcgtctttgcctccttcgtgagaaaagccagtgatgtggctgccatcagggctgctctg
gggcccgaaggacgcgacatcaagatcattagcaaaatcgagaaccacgaaggcgtgaag
aagtttgatgaaatcctggaggtgagtgacggcatcatggtggcacggggcgacctgggc
atcgagattccagccgagaaggttttcctggcccagaagatgatgattggacggtgcaac
ctggcgggcaagcccgttgtctgcgccacacagatgctggagagcatgatcactaagccg
cggccgacccgggcggagaccagtgacgtagccaacgctgtgctggacggagcagactgc
atcatgctgtcgggggagactgccaaaggccgatttcccgtggaggcagtgaagatgcag
cacgcgattgcccgggaggcagaggcggccgtgtaccaccggcagctgtttgaggagctg
cgccgggcagcgtccctgagccgcgatcccactgaggtcaccgccataggcgcggtggag
gccgccttcaagtgctgtgctgcagccatcatcgtgctgaccacgactggccgctcagca
cagttgctgtctcggtaccgacctcgggcagcggtcattgctgttacccgctctgcccag
gctgcccggcaggcccacctgtgccgaggggtcttccccttactctacagtgaacctcca
gaggccatctgggcagacgacgtggatcgccgggtccaatttggcattgaaagtggaaaa
ctccgtggcttcctccgcatgggggacctggtgatcgtggtgacaggctggcgccctggc
tctggccataccaacatcatgcgcgtgctgagcataccctga
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