Mirounga leonina (Southern elephant seal): 118014221
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Entry
118014221 CDS
T07472
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S isoform X1
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04010
MAPK signaling pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04270
Vascular smooth muscle contraction
mlx04723
Retrograde endocannabinoid signaling
mlx04725
Cholinergic synapse
mlx04726
Serotonergic synapse
mlx04727
GABAergic synapse
mlx04911
Insulin secretion
mlx04912
GnRH signaling pathway
mlx04921
Oxytocin signaling pathway
mlx04924
Renin secretion
mlx04925
Aldosterone synthesis and secretion
mlx04927
Cortisol synthesis and secretion
mlx04929
GnRH secretion
mlx04934
Cushing syndrome
mlx04935
Growth hormone synthesis, secretion and action
mlx05010
Alzheimer disease
mlx05020
Prion disease
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05207
Chemical carcinogenesis - receptor activation
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118014221 (CACNA1S)
04020 Calcium signaling pathway
118014221 (CACNA1S)
04024 cAMP signaling pathway
118014221 (CACNA1S)
04022 cGMP-PKG signaling pathway
118014221 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
118014221 (CACNA1S)
04929 GnRH secretion
118014221 (CACNA1S)
04912 GnRH signaling pathway
118014221 (CACNA1S)
04921 Oxytocin signaling pathway
118014221 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
118014221 (CACNA1S)
04924 Renin secretion
118014221 (CACNA1S)
04925 Aldosterone synthesis and secretion
118014221 (CACNA1S)
04927 Cortisol synthesis and secretion
118014221 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
118014221 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
118014221 (CACNA1S)
04270 Vascular smooth muscle contraction
118014221 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
118014221 (CACNA1S)
04725 Cholinergic synapse
118014221 (CACNA1S)
04726 Serotonergic synapse
118014221 (CACNA1S)
04723 Retrograde endocannabinoid signaling
118014221 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
118014221 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
118014221 (CACNA1S)
05020 Prion disease
118014221 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
118014221 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118014221 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
118014221 (CACNA1S)
05414 Dilated cardiomyopathy
118014221 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
118014221 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
mlx04040
]
118014221 (CACNA1S)
Ion channels [BR:
mlx04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
118014221 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
118014221
NCBI-ProteinID:
XP_034866251
LinkDB
All DBs
Position
Unknown
AA seq
1873 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
FRWKCHDVIKSKVFYWLVILVIALNTLSIASEHHNQPLWLTHLQDVANRVLLALFTIEML
MKIYGLGLHQYFMSIFNRFDCFVVCSGILEILLVEWGAMSPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDMEVRRSNFDNF
PQALISVFQVLTGEDWNSMMYNGIMAYGGPSYPGVLVCVYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEEKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLLVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEKECRGYYYVYKDGDPTQMELRPRQWIHSDFHFDNVLSAMMSLFTVSTFEGWPQLL
YQAIDSYKEDMGPVYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHY
NQSEEMNHISDILNVAFTIIFTLEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQVNRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEESTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTIQIQAGLR
TIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLPP
VMANQRPLQFAEIEMEELESPVFLEDFPQDPSTNPLAHANTNNANANIAYGNSNHSNRQV
FSSIHYEREFPGETETPAARGGAFGQPRRVLGPHSKSCVEKLKGQLTQREMTRSQAFPAP
CQRARAESPLPEERRSPTPGSLPEEATHSRRTKESSPRCQTPATAQLIQEALVRGGLDTL
AADADFVLVTGQALADACQMAPEEVEVAATELLKRQGSPEGLASALGRWSLRSSLGSLDL
HQGSQETLIPPRL
NT seq
5622 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggcctgaggaagaaacagcccaagaagcccgtt
cctgagattctgccaaggccaccccgggccttgttctgcttgaccctccagaatcctctg
aggaaggcctgcatcaacatcgtggaatggaaaccctttgagacaatcatcttgctcacc
atctttgccaactgtgtggccctggctgtgtacctgcccatgccagaagatgacaacaac
actctgaaccttggcctggagaaactggagtatttcttcctcattgtgttctcgattgaa
gccgccatgaagatcattgcctacggcttcctcttccaccaggatgcctacctgcgcagt
ggctggaatgtgctagacttcatcattgtcttcctgggggttttcaccgtgattctggaa
caggttaacgtcatccaaagcaacacagccccaatgagcagcaaaggggctggtctggac
gtcaaggccctgagagccttccgcgtgctcagacccctccggctggtgtccggggtgccg
agcctgcaggtggtcctcaactccatcttcaaggccatgctgcccctgttccacatcgcc
ctgcttgtcctctttatggtcatcatctacgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcattgggacagatatcgtggccacagtggagaacgag
aagccctcaccctgcgccaggacgggctcggggcgcccatgcacgatcaatggcagcgag
tgtcggggcggctggccggggcccaaccacggcatcacccacttcgacaatttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaatgatgccatcgggaacgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcattctcaacctggtgctgggtgtcctgagcggggaattcactaaggag
cgggagaaggccaagtccaggggaaccttccaaaagctccgggagaagcagcagctggag
gaggacctccggggctacatgagctggatcacgcagggcgaggtcatggacgttgaggac
ttgagagaagggaagctgtctttggatgaaggaggctccgacacagagagcctgtatgaa
atcgagggcttgaacaaaatcatccagttcgttcgccactggaggcagtggaaccgcatc
tttcgctggaagtgccatgacgtgatcaagtccaaggtcttctattggctggtgatcctg
gtcattgccctcaacaccctgtcaatcgcctccgagcaccacaaccagcctctgtggctg
acccacttgcaagacgtggccaaccgggtgctgctggccctcttcaccatcgagatgctg
atgaagatatacgggctgggactgcaccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggcatcctggagatcctgctcgtggaatggggcgccatgagc
cccctgggcatctccgtgctgcgctgcatccgcctccttaggatcttcaagatcaccaag
tactggacatctctgagcaacctggtggcgtccctgctcaactccatccgctctatcgcc
tccttactgctgctactcttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcgggggcaggtatgactttgaggacatggaggtacggcgcagcaactttgacaacttc
ccgcaggccctcatcagtgtcttccaggtcctgacaggtgaagactggaactccatgatg
tataacgggatcatggcctacggcggaccgtcctacccgggggtgctagtgtgtgtttat
ttcatcatccttttcgtctgtggcaattatatcctgctcaatgtcttcctggccattgct
gtggacaacctggctgaggccgagagcctgacttctgcccagaaggccaaggctgaggag
agaaagcgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaaatcagtg
atggccaagaagctggaacagaaacccaagggtgagggcatccctaccaccgccaagctg
aaaatcgatgaatttgaatctaatgtcaatgaagagaaggatccctacccttcagctgac
ttcccaggcgatgatgaagaagatgagcctgagattcccgtgagcccccgaccacgcccc
ctggctgagctgcagctgaaagagaaggcagtacccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcttgtgtcatcgtattgtcaatgctacctgg
ttcaccaacttcatcttgctcttcatcctgctcagcagtgctgcactggccgctgaggac
cccatccgggccgagtctgtgaggaatcagatccttgggtattttgacatcgcgttcacc
tctgtcttcactgtggagattgtcctcaagatgacgacctatggcgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctgctggtggtggccgtgtcactc
atctcaatgggactcgagtccagcgccatctccgtggtgaaaatcctgagggtgctgagg
gtgctcagacccctccgggccatcaacagagccaaaggcctgaagcacgtggtgcagtgc
gtgtttgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcattggcgtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacggagaaggagtgcaggggctattactacgtgtacaaggatggggacccc
acgcagatggagctgcgtccgcgccagtggatacacagcgatttccactttgacaatgtg
ctttcggccatgatgtcactcttcacggtgtccacctttgagggatggcctcagctactt
taccaggccatagactcatacaaggaggacatgggtcctgtctacaacaaccgggtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgtcatcgtcaccttccaggagcagggggagactgagtacaagaactgtgag
ctgaacaagaaccagcggcaatgtgtgcagtacgccctgaaggcccgcccgctgaggtgc
tacatccccaaaaacccataccagtaccaggtatggtatgtcgtcacctcctcctacttc
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcattac
aaccagtcagaggagatgaaccacatctcggacatcctcaatgtggccttcaccatcatc
ttcaccctggagatggtcctcaagctcatggcgttcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgattgtcatcggcagcatcatcgacgtcatcctcagt
gaaatcgatactttcctggcctccagcggaggactgtattgcctgggtggaggctgcggg
aacgttgatccagacgagagtgcccgcatctccagcgccttctttcgcctgttccgggtc
atgaggctgatcaagctgctgagccgggcggagggagtgcgcactctactgtggaccttc
atcaagtccttccaggccctgccctatgtggctctgctcatcgtcatgctcttcttcatc
tacgcggtcatcggcatgcagatgtttggtaagatcgccatggtggacgggacccaagta
aaccgcaacaacaacttccagacctttccacaagctgtgctactgcttttcaggtgtgcg
acaggagaggcatggcaggagattctgctggcctgcagctacggcaagttgtgtgaccct
gagtcggattatgccccgggtgaggagtccacgtgcggcaccaacttcgcctactactac
ttcatcagcttctacatgctctgtgctttcctgatcatcaacctctttgttgctgtcatc
atggacaactttgactacctcacacgggactggtccatcctgggccctcatcacctggat
gagttcaaggccatttgggcagagtatgacccagaggcgaagggcagaatcaaacacttg
gatgtggtgactctgctgagacggatccagccccctctgggcttcgggaagttctgcccc
caccgggtggcatgtaagcggctggtgggtatgaacatgcccttgaacagcgatggcacg
gtcaccttcaatgccacactcttcgctctggtccgcacggcactcaagatcaagacggaa
ggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctcctggaccaggtcattcctccaataggagatgatgaggtgactgta
gggaagttctacgccacatttctcatccaggagcacttccggaagttcatgaagcgccag
gaagagtattatgggtatcggcccaagaaggacactatacagatccaggccggactgcgg
accattgaggaagaggcagccccagagatccgccgcaccatctcaggagacctgacagcg
gaagaggagctggagagagccatggtggaggctgcgatggaggaagggatattccggagg
actggaggcctctttggccaggtggacaacttcctggaaaggaccaactccctgccccct
gtcatggccaaccagagacccctccagtttgctgagatagagatggaagagctggaatcg
cctgtcttcttggaggatttccctcaagatccaagcaccaaccctcttgctcatgccaat
accaacaatgccaacgccaacatcgcctatggcaacagcaaccatagcaacaggcaggtg
ttttccagcatccactacgaaagggagttccctggagagacagagacgcctgctgccaga
ggaggagcctttggccaaccccgaagggtcctgggaccccacagcaaatcctgtgtggaa
aagctaaaaggacagctgacccagagagaaatgaccagatcccaggcatttcctgcccct
tgccagcgtgccagggccgagtctcccctgcctgaggagaggaggagccccaccccaggg
tctctgcctgaggaagcaacccacagccgtaggaccaaggagagcagtcctcggtgccag
actccagcgacagcccagctgattcaagaggctctggttcgagggggcctggacaccttg
gcggctgatgctgactttgtcctggtgaccggccaggccctggcagatgcctgccagatg
gcaccagaggaagtggaggtggcagccacagagctactgaaaagacaagggtccccagag
ggtctggccagtgcccttggacgctggagcctcaggtcctctctgggcagccttgacctg
catcagggctcccaggagaccctgatcccccccaggctgtga
DBGET
integrated database retrieval system
