KEGG   Mirounga leonina (Southern elephant seal): 118015830
Entry
118015830         CDS       T07472                                 
Symbol
DDB2
Name
(RefSeq) DNA damage-binding protein 2
  KO
K10140  DNA damage-binding protein 2
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx03420  Nucleotide excision repair
mlx04115  p53 signaling pathway
mlx04120  Ubiquitin mediated proteolysis
mlx05161  Hepatitis B
mlx05169  Epstein-Barr virus infection
mlx05200  Pathways in cancer
mlx05202  Transcriptional misregulation in cancer
mlx05210  Colorectal cancer
mlx05212  Pancreatic cancer
mlx05213  Endometrial cancer
mlx05214  Glioma
mlx05216  Thyroid cancer
mlx05217  Basal cell carcinoma
mlx05218  Melanoma
mlx05220  Chronic myeloid leukemia
mlx05222  Small cell lung cancer
mlx05223  Non-small cell lung cancer
mlx05224  Breast cancer
mlx05225  Hepatocellular carcinoma
mlx05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    118015830 (DDB2)
  09124 Replication and repair
   03420 Nucleotide excision repair
    118015830 (DDB2)
 09140 Cellular Processes
  09143 Cell growth and death
   04115 p53 signaling pathway
    118015830 (DDB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118015830 (DDB2)
   05202 Transcriptional misregulation in cancer
    118015830 (DDB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118015830 (DDB2)
   05212 Pancreatic cancer
    118015830 (DDB2)
   05225 Hepatocellular carcinoma
    118015830 (DDB2)
   05226 Gastric cancer
    118015830 (DDB2)
   05214 Glioma
    118015830 (DDB2)
   05216 Thyroid cancer
    118015830 (DDB2)
   05220 Chronic myeloid leukemia
    118015830 (DDB2)
   05217 Basal cell carcinoma
    118015830 (DDB2)
   05218 Melanoma
    118015830 (DDB2)
   05213 Endometrial cancer
    118015830 (DDB2)
   05224 Breast cancer
    118015830 (DDB2)
   05222 Small cell lung cancer
    118015830 (DDB2)
   05223 Non-small cell lung cancer
    118015830 (DDB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    118015830 (DDB2)
   05169 Epstein-Barr virus infection
    118015830 (DDB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:mlx04121]
    118015830 (DDB2)
   03400 DNA repair and recombination proteins [BR:mlx03400]
    118015830 (DDB2)
Ubiquitin system [BR:mlx04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul4 complex
    Target recognizing subunit (DCAF)
     118015830 (DDB2)
DNA repair and recombination proteins [BR:mlx03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     Cul4-DDB2 complex
      118015830 (DDB2)
SSDB
Motif
Pfam: WD40_CDC20-Fz WD40 WD40_Prp19 WD40_WDHD1_1st Beta-prop_EML_2 Beta-prop_WDR75_1st WDR55 Beta-prop_RIG_2nd Beta-prop_WDR90_POC16_2nd Beta-prop_IFT140_1st Beta-prop_EIPR1 Beta-prop_WDR19_1st EIF3I Beta-prop_TEP1_2nd WD40_RFWD3 Beta-prop_TEP1_C Beta-prop_CAF1B_HIR1 NBCH_WD40 WD40_MABP1-WDR62_2nd Beta-prop_HPS5 WD_LRWD1 Beta-prop_Vps41 EF-hand_1
Other DBs
NCBI-GeneID: 118015830
NCBI-ProteinID: XP_034868692
LinkDB
Position
Unknown
AA seq 426 aa
MAPRKRPETQKTLEVAVRPKSKRSRSPRELEPEAKKLCVKGPGSSRRFDSGCLWAGLASL
QVPPSCSIVRALHHHKLGNAVRPSLQQGLQQAFLHSLASYRIFQKAAPFDRRATSLAWHP
THPSTLAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLDTNQFFTSSMEGTT
RLQDFKGNTLRVFTSSGTCNFWFCSLDVSARSRMVVTGDNVGHVILLNMDGRELWNLRMH
KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKSSFLHSLPHSHPVNAACFSPDGA
QLLTTDQKSELRVYSASQWDCPPSLIPHPHRHFQHLTPIKATWHPRYNLVVVGRYPDPNF
KSCTPHELRTIDVFDGNSGKMMYQLYDPESSGIISLNEFNPMGDTLASVMGYHILIWSQE
EAGMRT
NT seq 1281 nt   +upstreamnt  +downstreamnt
atggctcctaggaaacgcccagaaacccagaagaccctcgaggtggcagtgcgccccaag
agcaagaggagcagaagcccccgggagctggagcccgaggccaagaagctctgtgtgaag
ggccccggttctagcagaagatttgactcaggctgcctttgggcggggttggctagcctg
caggtcccgccatcatgcagcatcgtcagggccctccaccaccataagctgggcaatgct
gtccggccatcactacagcagggtctccagcaggcctttctgcactctctggcttcttac
cggatattccaaaaggctgccccctttgacaggagggccacatccttggcatggcaccca
actcaccccagcaccctggccgtgggttccaaagggggagatatcatgctctggaacttt
ggcataaaggacaaacccaccttcattaaagggatcggagctggagggagcatcactggg
ctgaagtttaaccctcttgataccaaccagtttttcacctcctcaatggagggaacaact
aggctgcaagactttaaaggcaacactctccgagtttttaccagctcaggcacctgcaac
ttctggttttgcagcctggatgtgtctgccagaagccgaatggtggtcacgggagacaat
gtggggcacgtgatcctgctcaacatggatggcagggagctttggaatctgagaatgcac
aaaaagaaagtgacccatgtggccctgaacccatgctgtgattggttcctggccacagcc
tctgtagaccaaacagtgaaaatctgggacctgcgccaggttagagggaaatccagcttc
ctccactcgctgccgcatagccatcctgtcaacgcagcttgtttcagtcctgatggagcc
cagctcctgaccactgaccagaagagtgagctccgggtttactcggcctcccagtgggac
tgccccccaagcctgatcccacaccctcaccgccacttccagcacctgacgcccatcaag
gcaacctggcatcctcggtacaacctcgttgtcgtgggccgatacccagatcctaatttc
aaaagctgtaccccccatgaattaaggacgatcgatgtgtttgatggaaactcagggaag
atgatgtatcagctctatgacccagaatcttctggtatcatttcgctcaatgagttcaat
cccatgggggacacgctggcctctgtgatgggttatcacattctcatttggagccaggag
gaagctgggatgcggacatga

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