KEGG   Mirounga leonina (Southern elephant seal): 118017467
Entry
118017467         CDS       T07472                                 
Symbol
CACNA1B
Name
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform X1
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04020  Calcium signaling pathway
mlx04721  Synaptic vesicle cycle
mlx04723  Retrograde endocannabinoid signaling
mlx04725  Cholinergic synapse
mlx04726  Serotonergic synapse
mlx04727  GABAergic synapse
mlx04728  Dopaminergic synapse
mlx04930  Type II diabetes mellitus
mlx05016  Huntington disease
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05032  Morphine addiction
mlx05033  Nicotine addiction
mlx05207  Chemical carcinogenesis - receptor activation
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118017467 (CACNA1B)
   04020 Calcium signaling pathway
    118017467 (CACNA1B)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    118017467 (CACNA1B)
   04725 Cholinergic synapse
    118017467 (CACNA1B)
   04728 Dopaminergic synapse
    118017467 (CACNA1B)
   04726 Serotonergic synapse
    118017467 (CACNA1B)
   04723 Retrograde endocannabinoid signaling
    118017467 (CACNA1B)
   04721 Synaptic vesicle cycle
    118017467 (CACNA1B)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    118017467 (CACNA1B)
  09164 Neurodegenerative disease
   05016 Huntington disease
    118017467 (CACNA1B)
   05020 Prion disease
    118017467 (CACNA1B)
   05022 Pathways of neurodegeneration - multiple diseases
    118017467 (CACNA1B)
  09165 Substance dependence
   05032 Morphine addiction
    118017467 (CACNA1B)
   05033 Nicotine addiction
    118017467 (CACNA1B)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    118017467 (CACNA1B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:mlx04040]
    118017467 (CACNA1B)
Ion channels [BR:mlx04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   118017467 (CACNA1B)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel Phage_TAC_15
Other DBs
NCBI-GeneID: 118017467
NCBI-ProteinID: XP_034871223
LinkDB
Position
Unknown
AA seq 2238 aa
MILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKG
SYLRNGWNVMDFVVVLTGILATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKA
MVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNGTDPDPVGDFPCGKEAPARLCEG
DTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPL
IIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVM
LAEEDKNAEEKSPLDAVLKRAATKKSRNDLIHAEEGEDRFADLCAVGSPFTRSSLKSGKT
ESSSYFRRKEKMFRFFIRRMVKAQSFYWAVLCVVALNTLCVAMVHYNQPQRLTTALYFAE
FVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSIFEVVWAAIRPGASFGISVLR
ALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFK
DETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNY
TLLNVFLAIAVDNLANAQELTKDEEEMEEAANQKLALQKAKEVAEVSPMSAANISVAAAR
PQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRYATTRHLRPDMKTHLDRPL
VVELGRDGPRVASGGKARPEGPEAAEGADPPRRHHRHRDKAAAPAPAPAPAAAGEDRGDA
PKAERAEPGAREERARPHRSRSKETRSERGRGPGPEGGRRHHRRASPEEAAEREPRRHRA
HRHAPAQGKEGGAAAAKGERRARHRGGPRAGPREAGSGEEPARRHRARHKALPTHEDVEK
EAAEKEGEAEDRDKEKELRNHQPKEAHCDLEASGIMGVGPVHALPSTCLQKVEEQPEDAD
NQRNVTRMGSQPSDLSATVHIPVTLTGPPGETTTVPSGNVDLESQAEGKKEVEADDVMRS
GPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSPR
NNALKYMDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGS
KGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILVVYMLFMFIFAVI
AVQLFKGKFFYCTDESKGLERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLF
TVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITF
QEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQDKQSFQYKTWTFVVSPPFEYFIMA
MIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFD
FVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKAL
PYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHE
IMLSCLSNQACDEHANASECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSS
ILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMN
MPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISSVWANLPQKTLDL
LVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQIHQATGGLSQMGPVSLFHPLKATLEQ
TQPAVLRGARVFLRQKSSASLSNGGAVQTQESGIKESVSWGTQRTQEVPSEARTPLERGH
STEIPVVQPGKPAVDVQMQSMALRGPDGEPQLGLESQGRAASMPRLAAETQPAPNASPMK
RSISTLAPQRPHMAHLCSAALDRAPASQAAPHHHHRCHRRRDRKQKSLEKGPSLSADTDG
APSSVAGPGPPPGEGPTGCRRERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPSQP
KPSLSSHPTSPTAGQEPGPLRPGGGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSV
TYKTANSSPVHFAGAQTSLPTFSPGRLSRGLSEHNALLQRDPLSQPLAAGSRIGSDPYLG
QRLDSEDTARTQPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLS
SGGRVRHSYHHPDQDHWC
NT seq 6717 nt   +upstreamnt  +downstreamnt
atgatcctggccacaatcatcgccaactgcatcgtgctggcgctggagcagcacctcccc
gacggggacaagacgcccatgtccgagcggctggacgacacagagccctatttcattggc
atcttctgctttgaggcggggatcaagatcatagccctgggctttgtcttccacaagggc
tcctacttacggaacggctggaacgtcatggacttcgtggtggttctcacagggatcctg
gccacggctggcactgactttgacctgcggaccctgcgggctgtgcgcgtgctcaggccc
ctgaagttggtgtctgggattccgagtttgcaggtggtgctcaagtccatcatgaaggcc
atggttccactcctgcagattgggttgcttctcttctttgccatccttatgttcgcgatc
atcggcctcgagttctacatgggcaaattccacaaggcctgtttccccaacggcacagat
ccagatccagtgggtgacttcccctgtggcaaagaggccccagcccggctgtgtgagggt
gacactgaatgtcgggaatactggccagggcccaactttggcatcaccaactttgacaat
atcctgtttgccatcttgacggtattccagtgcatcaccatggagggctggactgacatc
ctctacaacacaaatgatgcagctggtaacacctggaactggctctacttcatccctctc
atcatcattggctccttcttcatgctcaacctggtgctgggcgtgctctcaggagagttt
gccaaggagcgtgagagggtcgagaaccgccgggccttcttgaagcttcgccggcagcag
cagatcgagcgggagctcaatgggtacctggagtggatcttcaaggctgaggaagtcatg
ctggccgaggaggacaagaatgcggaggagaagtcccctctggatgcagtgttgaagaga
gcagccaccaagaagagtcggaatgacctgattcatgctgaggagggggaagaccggttt
gcagacctctgtgccgtgggatcccccttcacccgttccagcctcaagagcggaaagaca
gagagctcgtcatacttccgtaggaaggagaagatgttccggttcttcatccggcgcatg
gtgaaggcgcagagcttctactgggcggtgctgtgtgtggtggccctgaatacgctgtgc
gtggccatggtgcattacaaccagccgcagcggctcaccacggcgctgtactttgcagag
tttgttttcctgggtctcttcctcacagagatgtccctgaagatgtatggcctggggccc
agaagctacttccggtcctcattcaactgcttcgactttggggtcattgtggggagcatc
tttgaagtggtctgggctgccatcaggccaggagcctccttcgggatcagtgtgctgagg
gcactccggctgctgaggatcttcaaagtcacaaagtactggagctccctgcggaacctg
gtggtgtctctgctcaactccatgaagtccatcatcagcctcctcttcctgctgttcctg
ttcatcgtggtcttcgctctgctgggcatgcagctgtttgggggacagttcaactttaag
gatgagaccccgacaacgaactttgacactttccccgcggccattctcactgtcttccag
atcctaacaggagaggattggaatgcagtgatgtatcacgggatcgagtcgcaaggtgga
gtcagcaaaggcatgttctcctccttttacttcattgtcctgacgctgtttggaaattac
actctgctgaatgtcttcctggccatcgccgtggacaacctcgccaatgctcaggagctg
accaaggacgaagaggagatggaagaagcagccaatcagaagcttgctctgcaaaaggcc
aaagaagtggctgaagtcagtcccatgtctgccgccaacatctccgttgctgctgccagg
ccgcagaactcggccaaggcgcgctcggtgtgggagcagcgcgccagccagctgcggctg
cagaacctgagggccagctgcgaggcgctgtacagcgagatggaccccgaggagaggctg
cgctacgccaccacgcgccacctgcggcctgacatgaagacgcacctggaccggccgctc
gtggtggagctcggccgcgacgggccgcgggtcgcctcgggcggcaaggcccggcccgag
ggcccggaggctgccgagggcgcggacccgccgcgcaggcaccaccggcaccgcgacaag
gccgcggccccggccccggccccggccccggcggcagcgggggaggacaggggggacgcg
ccgaaggccgagcgcgcggagcccggggcccgggaggagcgcgcgaggccgcaccgcagc
cgcagcaaggagacccggagcgagcgcggccgcggcccgggccccgagggcggccggcgc
caccaccggcgcgcctccccagaggaggcggccgagcgggagccgcggcgccaccgcgcg
cacaggcacgcacccgcccagggcaaggaaggcggcgcggccgcggccaagggcgagcgg
cgagcgcgccaccgcggcggcccgcgggccgggcccagggaggccgggagcggggaggag
ccggcgcggcggcaccgggcccggcacaaggcgctgcccacgcacgaggatgtggagaag
gaggcggcggagaaggagggcgaggccgaggaccgggacaaggagaaggagctccggaac
caccagcccaaggaggcacactgtgacctggaggccagtgggataatgggtgtgggccct
gtgcatgcactgcccagcacttgtctacagaaggtggaggaacagccagaggatgcagat
aatcagcggaatgtcacacggatgggcagtcaaccgtccgacctgagtgctactgtgcat
atcccagtgacgctgaccggccctcctggggagaccacaactgttcccagtggtaacgtg
gacctggaaagccaagctgaggggaagaaggaggtggaagctgatgatgtgatgaggagt
ggcccgcgacccatcgtcccatacagctccatgttctgtttaagccccaccaacctgctc
cgccgcttctgccattatatcgtgaccatgcggtactttgagatggtcattctcgtggtc
atcgccctgagcagcattgccctggctgccgaggatccagtgcggacagactcgcccagg
aacaacgctctgaagtacatggactacattttcacaggcgtcttcacctttgagatggtg
atcaagatgattgatttgggactgctcctacaccctggggcctacttccgggacttatgg
aatattctggacttcatcgtggtcagtggggccctggtggcatttgccttctcaggatcc
aaagggaaagacatcaataccatcaagtccctgagagtcttgcgtgtcctgcggcccctc
aagaccataaaacggctgcctaagctcaaggctgtgtttgactgtgtggtgaactcgctg
aagaatgtcctcaacatcctggtcgtctacatgctcttcatgttcatatttgctgtcatt
gcggtgcagctcttcaaagggaagtttttctactgcacggatgagtctaaggggctggag
agggactgccggggtcagtatttggattatgagaaggaggaggtggaagctcagccccgg
cagtggaagaaatacgactttcactacgacaatgtgctctgggctctgctgacgctgttc
acagtgtccacaggagaagggtggcccatggtcctgaaacactctgtggacgccacctat
gaggagcaaggcccaagccccgggtaccgcatggagctgtccatcttctacgtggtctac
tttgtggtcttccccttctttttcgtcaacatctttgtggccttgatcatcatcaccttc
caggagcagggggacaaggtgatgtctgaatgcagcctggagaagaacgagagggcttgc
atcgacttcgccattagtgccaagcccctgacgcggtacatgccccaggacaagcagtcg
ttccagtacaagacatggacttttgtggtctcgcctcccttcgagtacttcatcatggcc
atgatcgccctcaacacagtggtgctaatgatgaagttctatgacgcaccgtatgaatat
gagctaatgttgaaatgcctgaacattgtgttcacatccatgttctccatggaatgcgtg
ctgaagatcatcgcttttggggtgctgaactatttcagagatgcctggaatgtctttgac
tttgtcactgtgttgggaagtattactgatattttagtaacagagattgcggaaacgaac
aatttcatcaacctcagctttctccgcctcttccgtgctgcccggctcatcaagctgctg
cgccagggctataccatccgcatcctgctgtggaccttcgtccagtccttcaaggccctg
ccctacgtgtgtctgctcatcgccatgctgttcttcatctacgccatcatcggcatgcag
gtttttggaaatattgccctggatgatgacaccagcatcaaccggcacaacaacttcagg
acgtttttacaagccttgatgctgttgttcaggagtgccactggggaggcctggcacgag
atcatgctgtcttgtctcagcaaccaggcctgtgatgagcacgccaatgccagtgagtgt
gggagcgactttgcctacttctactttgtctccttcatcttcctttgctcctttctgatg
ttgaacctctttgtggccgtgatcatggacaattttgagtaccttacacgggactcttcc
atcctagggcctcaccacctggacgagttcatccgggtctgggctgagtacgacccggcc
gcgtgtgggcgcatcagttacaatgacatgtttgagatgctgaaacacatgtccccaccc
ctggggctggggaagaaatgccctgctcgagttgcatacaagcgcctggttcgcatgaac
atgcccatctccaatgaggacatgactgtccacttcacatccacgctgatggccctcatt
cggactgcactggagatcaagctggctccagccggcaccaagcagcatcagtgtgatgca
gagttgaggaaggagatttcctctgtgtgggccaatctgccccagaagaccctggattta
ctggtgccaccccataaacccgatgagatgaccgtaggaaaagtgtatgcagctctgatg
atatttgacttctacaaacagaacaagaccaccagagaccagattcaccaggccacggga
ggcctgtcccagatgggccctgtgtccctgttccaccctctgaaggccacgctggagcag
acacagccggctgtgctccgaggagcccgggttttccttcggcagaagagctctgcgtcc
ctcagcaacggcggggccgtacaaacccaggagagtggcatcaaggagtctgtttcctgg
ggcactcagaggacccaggaggtaccctctgaggcaaggacacccctggagcgtggccac
tctacagagatcccagtggtgcagccaggaaaaccggctgtggatgtccagatgcagagc
atggccctgagaggtcctgacggggagccccaactcggactggagagccagggacgagcg
gcctccatgccccgcctggctgcagagactcagccggcccccaacgccagccccatgaag
cgctccatctccacactggcgccccagcgtccccacatggctcatctctgcagcgctgcc
ctggaccgcgccccggccagccaggctgcgccccatcaccaccaccgctgccatcgccgc
agagacaggaagcagaagtccttggagaaggggcccagcctgtccgcagacacagatggc
gcacccagcagtgttgcagggccaggcccacccccgggagagggtcccacaggctgccgg
agggagcgcaggcaggagcggggccggtcccaagagcggaggcagccctcttcctcttcc
tcggagaagcagcgtttctactcctgtgaccgttttgggggccgggagccctcgcagccc
aaaccctccctcagcagccaccccacgtcaccaacagctgggcaggagccaggacccctg
agaccgggtggtggctcagtgaacgggagccccttgttgtcaacatccggtgctagcacc
cctggccgtggtgggcggaggcagctcccccagactccgctgaccccccgtcccagtgtc
acctacaagacggccaactcttcgcctgtccactttgctggggcgcagaccagcctcccc
accttttccccgggccggcttagccggggcctttccgaacacaacgctctgctccagaga
gaccccctcagccagcctctggccgccggctctaggatcggctctgacccttacttgggg
cagcgtctggacagtgaggacactgcccgcacccagcccgaggacacgcttaccttcgag
gaggctgtggccaccaactcaggccgctcctcccggacttcctacgtgtcctctctgacc
tcccagtcacaccccctccgccgcgtgcccaacggctaccactgcaccctgggactcagc
tcgggcggccgtgttcggcacagctaccaccaccccgaccaagaccactggtgctag

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