Mirounga leonina (Southern elephant seal): 118017539
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Entry
118017539 CDS
T07472
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2 isoform X1
KO
K05730
guanine nucleotide exchange factor VAV
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04015
Rap1 signaling pathway
mlx04024
cAMP signaling pathway
mlx04062
Chemokine signaling pathway
mlx04510
Focal adhesion
mlx04517
IgSF CAM signaling
mlx04650
Natural killer cell mediated cytotoxicity
mlx04660
T cell receptor signaling pathway
mlx04662
B cell receptor signaling pathway
mlx04664
Fc epsilon RI signaling pathway
mlx04666
Fc gamma R-mediated phagocytosis
mlx04670
Leukocyte transendothelial migration
mlx04810
Regulation of actin cytoskeleton
mlx05135
Yersinia infection
mlx05205
Proteoglycans in cancer
mlx05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
118017539 (VAV2)
04024 cAMP signaling pathway
118017539 (VAV2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
118017539 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118017539 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118017539 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
118017539 (VAV2)
04660 T cell receptor signaling pathway
118017539 (VAV2)
04662 B cell receptor signaling pathway
118017539 (VAV2)
04664 Fc epsilon RI signaling pathway
118017539 (VAV2)
04666 Fc gamma R-mediated phagocytosis
118017539 (VAV2)
04670 Leukocyte transendothelial migration
118017539 (VAV2)
04062 Chemokine signaling pathway
118017539 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
118017539 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
118017539 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118017539 (VAV2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
SH3_2
CAMSAP_CH
CH
SH3_1
SH3_9
SH2
SOS1_NGEF_PH
PH
C1_1
DUF7145
RHG20_PH
PLU-1
C1_2
SH2_2
CDC24
DH_Alsin
zf-RING-like
ANC1_spectrin
PH_10
Motif
Other DBs
NCBI-GeneID:
118017539
NCBI-ProteinID:
XP_034871390
LinkDB
All DBs
Position
Unknown
AA seq
839 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAAVFDLAQALRDGVLLCQLLHNLAPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHHV
AQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
RQPMKMGMSEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMTPLRLVLSPADMTAIFINLE
DLIKVHHSFLRAIDVSMMAGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASRE
DFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEYGRPKIDGELKVRSIVNHTKQDR
YLFLFDKVVIVCKRRGYSYELKEVIELLFHKMTDDPMNNKDVKKWSYGFYLIHLQGKQGF
QFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACRMFLRGTFYQ
GYLCTKCGVGAHKECLEVTPPCKISSPADLDASGAGPGPKMVAVQNYHGNPAPPGKPVLT
FQTGDVIELLRGDPESQWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSREIDYTA
YPWFAGNMERQQTDNLLKSHTSGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDSWIH
ITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERAASRASSRSPVFTPRVIG
TAVARYNFAARDMRELSLREGDVVKIYSRIGGDQGWWKGEANGRIGWFPSTYVEEEGIQ
NT seq
2520 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggcggcggtgttcgacctggcgcaggcgctgcgcgacggc
gtcctcctgtgtcagctgctgcacaacctcgcccccggctccatcgacctcaaggacatc
aacttccggccgcagatgtcccagttcctgtgcttgaagaacatccgcaccttccttaaa
gtctgccacgataaatttggactgagaaacagcgagctgtttgacccctttgacctcttc
gacgtccgagactttgggaaggtcatctctgccgtgtccagactctccctgcaccacgtg
gctcagaacaaagggatcaggccctttccctcggaggagaccaccgagaatgacgacgat
gtgtaccgcagcctggaggaactggcggacgagcatgacctcggggaggacatctatgac
tgcgtcccgtgtgaggacgagggggacgacatctatgaggacattatcaaggtggaggta
cggcagcccatgaaaatgggcatgtccgaggatgacaagaggaattgctgcttattggag
attcaggagaccgaggccaagtactaccggaccctggaggacatcgagaagaactatatg
acccccctgaggctggtgctgagcccggcggacatgacagccatcttcatcaacctggag
gacctgatcaaggtgcatcacagctttctgcgggccatcgacgtgtccatgatggcgggg
ggcagcactctggccaaggtcttcctcgatttcaaggaaaggctcctgatctacggggaa
tactgcagccacatggagcacgctcagaacacgctgaaccagctcctcgccagccgggaa
gacttcagacagaaggtcgaggaatgcacgctgaaggtccaggacgggaagtttaagctt
caagacctgctcgtggtccccatgcagagagtgctcaaataccacctcctcctgaaggaa
cttctgagccattccaccgatcggcccgagagacagcagctcaaagaagctctagaagcc
atgcaggacttagcgatgtacataaacgaagttaaacgggacaaggagaccctgaagaaa
atcagcgaatttcagagttctatagaaaacttgcaagtgaaactggaggagtatgggagg
ccgaagatcgacggggaactgaaggtccggtccatagtcaaccacaccaagcaagatagg
tacttgttcctgtttgacaaggtggtcattgtctgcaagaggagaggctacagctacgag
ttgaaggaggtcatcgagctgctcttccacaagatgactgacgaccccatgaacaacaag
gacgtcaagaagtggtcctacggtttctatttaattcatctgcaaggaaagcagggcttc
cagttcttctgcaagaccgaagacatgaagcggaaatggatggagcagttcgagatggcc
atgtccaacatcaagccagacaaagccaatgctaaccaccacagcttccagatgtacact
ttcgacaagactaccaactgcaaagcctgtaggatgttcctcaggggcacattttaccag
ggctacctatgcaccaagtgtggtgtcggggcccataaggagtgtctggaagtgacgcct
ccctgcaagatcagttctcccgccgacttggacgcctctggagcaggaccgggtcccaag
atggtggccgtgcagaattaccatggcaacccagctccccccgggaagccagtgctgacc
ttccagacgggcgatgtgatcgagctgctgagaggcgaccccgagtctcagtggtgggag
ggtcggctggtgcaaaccaggaagtcaggctactttcctagctcgtccgtgaagccctgc
cccgtggacggaaggccgcccatcagccggccgccatcccgggagatcgactacaccgcc
tacccctggtttgcgggcaacatggaaaggcagcagaccgacaacctgctcaagtcgcac
accagcgggacctacctaatcagggagcggccggccgaggcagagcgctttgccataagc
atcaagttcaacgacgaggtgaaacacatcaaggtggtggagaaggacagctggatccac
atcacagaagcgaagaaatttgaaagcctcttggagctggtggagtactaccagtgccac
tcgctcaaggagagcttcaagcagctggacaccacgctcaagtacccctacaagtcaagg
gagcgcgcggcctccagggcctccagccggtccccagtgttcacgccccgtgtcattggc
acggccgtggccaggtacaactttgccgcccgggacatgcgcgagctctcgctgcgggaa
ggtgacgtggtgaagatctatagccgcattggcggggaccagggctggtggaagggcgag
gccaacggacggatcggctggtttccttcaacatacgtagaggaggagggcatccagtga
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