Mirounga leonina (Southern elephant seal): 118017579
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Entry
118017579 CDS
T07472
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04012
ErbB signaling pathway
mlx04014
Ras signaling pathway
mlx04110
Cell cycle
mlx04360
Axon guidance
mlx04722
Neurotrophin signaling pathway
mlx05200
Pathways in cancer
mlx05206
MicroRNAs in cancer
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05220
Chronic myeloid leukemia
mlx05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
118017579 (ABL1)
04014 Ras signaling pathway
118017579 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
118017579 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
118017579 (ABL1)
09158 Development and regeneration
04360 Axon guidance
118017579 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118017579 (ABL1)
05206 MicroRNAs in cancer
118017579 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
118017579 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
118017579 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
118017579 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118017579 (ABL1)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
118017579 (ABL1)
Protein kinases [BR:
mlx01001
]
Non-receptor tyrosine kinases
ABL family
118017579 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
118017579
NCBI-ProteinID:
XP_034871493
LinkDB
All DBs
Position
Unknown
AA seq
1150 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRKAAEHKDPTDVPETPHSKGPGETDPLDHEPPVSPLLPRKERGPQD
GALNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKAPSEEEGRET
SNGAPALTPSDAAEPAKSPKPSSGAGVPNGAFRESGGAGFRSPHLWKKSSTLTSSRLAAG
EEESGSSSGKRFLRSCSASCVPHGARDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPA
LPRKRASENRSDQVTRGTVTPPPRLVKKTEDAADEVFRDAGESSPGSSPPSLTPKLLRRQ
VAGAPSSGLPHKDEAGKSGALGTPATAEPVPPASRAGPGASGGTGKAPTEEPRARRHKPS
SESPGRDKGKLSKLKPVPPPPPPASGGKAGKPSQSLSQEAAGEAGTGGKAKATAVVVDAV
NSDTVRPGPLGEGVKKPVLPSMPKPQSSSKPAGTPTSPAPSPSTLPSASSALAADQPAST
AFIPLISTRVSLRKTRQPPERIASGTITKGVVLDGTEALCLAISKNSEQMASHSAVLEAG
KNLYTFCVSYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSS
VKEISDIVQR
NT seq
3453 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccagagaaggccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggaatcatcgaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcagaggccagtagcatctgactttgagccccaaggt
ctcagcgaagcagctcgttggaactccaaggaaaaccttcttgctggccccagtgaaaat
gaccccaaccttttcgttgcactgtatgattttgtggccagtggggacaacaccctaagt
ataactaaaggtgagaagctccgggttttaggctacaatcacaatggggaatggtgtgaa
gcccaaaccaaaaatggccaagggtgggtcccaagcaactatatcacgccagtcaacagt
ctggagaaacattcctggtatcacgggcccgtgtcccgcaacgcggctgaatacctgctg
agcagtgggatcaacggcagcttcttggtccgggagagcgagagcagtcctggccagagg
tccatctcgctgagatacgaagggagggtgtaccactacaggatcaacactgcttccgat
ggcaagctctacgtctcctcagagagccgcttcaacactttggctgagttggttcatcat
cactcgactgtggcggacggcctcatcaccactctccattacccggcccccaagcgcaac
aagcccaccgtttacggcgtgtcccccaactacgacaagtgggagatggagcgcacggac
atcaccatgaagcacaagctgggcggaggccagtacggggaggtgtacgaaggcgtgtgg
aagaaatacagcctgacggtggccgtgaagaccttgaaggaggacaccatggaggtggag
gagttcttgaaagaagctgcagtaatgaaagagatcaagcaccccaatctagtacagttg
ctcggggtctgtacccgggagcccccgttctatataatcactgagttcatgacctatggg
aacctgttggattacctgagagagtgtaaccggcaggaggtgaacgccgtggtactgctg
tacatggccactcagatctcgtcggccatggagtacctcgagaagaagaacttcatccac
agagatcttgctgcccggaactgcctggtaggggagaaccacttggtgaaggtggctgat
ttcggcctgagcaggttaatgacaggggatacctacacagcccatgccggggccaagttc
ccgatcaagtggacggcgccagaaagcctggcctacaacaagttctccatcaagtccgac
gtctgggcttttggagtattgctttgggaaattgccacctatggcatgtcgccttacccg
ggaattgacctgtcccaggtgtatgagctgctagagaaggactaccgcatggagcgcccg
gaaggctgcccggagaaggtttatgaactgatgcgcgcatgttggcagtggaatccctct
gaccggccctcctttgctgaaatccaccaagcctttgagacaatgttccaggaatccagc
atatcagatgaagtggaaaaggaactggggaaaaaaggtgtgcgaggggttgcaagtact
ttgctgcaggccccagagctgcccaccaagacaagaacctccaggaaagctgcggagcac
aaagaccccactgatgtgcctgagacgccccactccaagggcccaggagagaccgatcct
ctggaccatgagcctcctgtgtctccactgctccctcggaaagaacgaggtccccaggac
ggcgccctaaatgaagatgagcgccttctccccaaagacaaaaagaccaatttgttcagt
gccttgatcaagaagaagaagaaaacagccccaacccccccgaaacgcagcagctccttc
cgggagatggacggccagcccgagcgcaaggcgcccagtgaggaagagggccgagaaacc
agcaacggggcgccagccctcacaccctcggacgcagccgagccagccaagtccccaaag
cccagcagcggagctggcgtccccaatggagccttccgggagtcagggggtgcaggcttc
cggtctccccacctgtggaaaaagtccagcacactgaccagcagccgcctggcggccggt
gaggaggagagtggcagcagctccggcaagcgcttcctaaggtcctgctctgcctcctgc
gtgcctcacggggccagggacacagagtggaggtctgtcaccctgcctcgggacctgcag
tccacggggaggcagttcgactcgtccacgtttggagggcacaaaagcgagaagccagct
ctgcctcggaagcgggcaagtgagaacaggtccgatcaggtgaccagaggcacggtgact
cccccacccaggctggtgaaaaagaccgaggatgcagcggacgaggtcttccgagacgcg
ggggagtccagccccggctccagccctcccagtctgactccgaaactcctccgcaggcag
gtcgcgggggctccttcctctggcctcccccacaaggacgaggccgggaagtccggtgcc
ttggggacacctgccacagctgagccggtgccccccgccagcagagcagggccaggcgcg
tccggagggactggcaaggcccccaccgaggaacccagagcgaggaggcacaagccctcc
tctgagtccccagggagagacaaggggaaactgtccaagctcaaacctgtcccgccgccc
ccgccaccagcctccggtgggaaggccgggaagccctctcagagcctgagccaggaagca
gctggggaggccggcactggcgggaaagccaaagccacggccgtggtcgtggatgctgtg
aacagtgacaccgtcaggcccggtccgctgggagagggcgtcaaaaagcccgtgctcccg
tccatgccaaagccacagtcgtccagcaagccggcggggaccccaaccagcccagctccc
tccccctccaccttgccatcggcatcctccgccctggctgcggaccagccagcctccact
gccttcatccctctcatatcgacccgtgtgtcacttcggaaaacccgccagcctccggag
cggatcgccagtggcaccatcaccaagggcgtggtcctggatggcacggaggctctgtgc
ctggccatctccaagaactccgagcagatggccagccatagcgccgtgctagaagccggc
aagaacctctacacgttctgtgtgagctatgtggattccatccagcaaatgaggaacaag
ttcgccttccgcgaggccatcaacaaactggagaataatctccgggagcttcagatctgc
ccggcgacagcagggagtggcccagcggccactcaggacttcagcaaactcctcagctcc
gtgaaagagatcagtgacatcgtacagaggtag
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