Mirounga leonina (Southern elephant seal): 118017649
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Entry
118017649 CDS
T07472
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00790
Folate biosynthesis
mlx01100
Metabolic pathways
mlx01240
Biosynthesis of cofactors
mlx01523
Antifolate resistance
mlx04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
118017649 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
118017649 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
118017649 (FPGS)
Enzymes [BR:
mlx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
118017649 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
118017649
NCBI-ProteinID:
XP_034871635
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All DBs
Position
Unknown
AA seq
588 aa
AA seq
DB search
MSQARCHLRAALFLAAVSPRGATTGVTARRGLSAWPAPQEPGMEYQDAVRTLNTLQTNAG
YLEQVKRQRRDPQTQLEAMKLFLARSGLQVEDLDQLNIIHVTGTKGKGSTCAFTERVLRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWLLYHRLEETKDSSSCVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEEI
AWQKGGIFKRGVPAFTVLQPDGPLAVLWDRAQQISCPLYLCPPLEALEEGGPPLALGLDG
EHQRFNAALALQLARCWLQQKGHQGLGELKVSRPSVLRQMPLAPVFQPTPHMRHGLRDTE
WLGRTQVLRRGPLTWYLDGAHTASSVQACVRWFHQALLQGHRPGRGPEVRILLFNSTGDR
DSAALLKLLQPCQFDYAVFCPNLTEVSSAGNADQQNFMVTLDQVLLRCLAHQQYWSHLAE
AQASPDPWSAPSPEPGEPTSSLLASHPPRTHSTSSLVFSCISHALQWISQGRDPVFQPPS
PPQGLLAHPVAGSGAGVLREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1767 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcaggcacgctgccacctgcgtgccgctctcttcctggcagcagtttctccgcgc
ggtgcaacgaccggggtcacggcgcggcgagggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtatcaggatgctgtgcgcacactgaacaccctgcagaccaatgctggc
tacctggagcaggtaaagcgccagcggcgtgaccctcagacacagctggaagcgatgaag
ctgttcttggcccggagtgggctgcaggtggaagacttggaccagctgaacatcattcac
gtcactgggaccaaggggaagggttccacgtgtgccttcaccgaacgtgttctccgcagc
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgggagcggatc
cgcatcaacgggcagcccataagccccgagctcttcaccaagcacttttggctcctctac
caccggctggaggagaccaaggacagcagcagctgtgtctccatgcctgcctacttccgc
ttcctcacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaagtgggcatcggtggcgcttacgactgcaccaacatcatcaggaagcctgtggtgtgt
ggcgtctcttctcttggcatcgaccacaccagccttctgggggacacagtggaggagatc
gcatggcagaaagggggcatcttcaagcgtggcgtccctgccttcacggtgctccagcct
gacggtcccctggcggtgctgtgggaccgtgcccagcagatctcctgtcctctctacctg
tgcccaccactggaagccctggaggaaggggggccgccgctggccctgggcctggatgga
gagcaccagcggttcaacgccgccttggccttgcagctggctcgctgctggctacagcaa
aagggccaccagggcctcggggagctgaaggtgtctcggcccagcgtcttgcggcagatg
cccctggcacccgtgttccagcccacgccccacatgcggcatgggcttcgggacacggag
tggctgggccggacacaggtgctgcggcgcgggcccctcacctggtacctggacggcgcg
cacaccgccagcagcgtgcaggcctgcgtgcgctggttccaccaggcgctgctccaaggc
cacaggcccggccgcggccctgaggtacgcatcttgctcttcaactccaccggggaccgg
gattccgccgccctgctgaagctgctgcagccctgtcagtttgactatgctgttttctgc
cctaacctgacagaggtgtcgtctgctggcaacgcagaccagcagaacttcatggtgacc
ctggaccaggtgctgctccgttgcctcgctcaccaacagtactggagccatctggccgag
gcgcaggccagcccagacccctggagcgcccccagtccggagcctggtgagcccacatcc
tcgctgctggcttcccacccaccccgcacgcatagcaccagctccctcgtcttcagctgc
atctcgcacgccctgcagtggatcagccaaggccgggaccctgtcttccagccacccagt
cccccacagggcctccttgcccaccctgtggcaggcagcggggccggcgtgctccgcgag
gctgccgccatccatgtacttgtcacgggcagcttgcacctggtgggcggcgtcctgaag
ctgctggagcctgccctgtcccagtag
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