KEGG   Mirounga leonina (Southern elephant seal): 118017899
Entry
118017899         CDS       T07472                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04060  Cytokine-cytokine receptor interaction
mlx04068  FoxO signaling pathway
mlx04144  Endocytosis
mlx04218  Cellular senescence
mlx04350  TGF-beta signaling pathway
mlx04371  Apelin signaling pathway
mlx04380  Osteoclast differentiation
mlx04390  Hippo signaling pathway
mlx04520  Adherens junction
mlx04659  Th17 cell differentiation
mlx04926  Relaxin signaling pathway
mlx04933  AGE-RAGE signaling pathway in diabetic complications
mlx05142  Chagas disease
mlx05161  Hepatitis B
mlx05166  Human T-cell leukemia virus 1 infection
mlx05200  Pathways in cancer
mlx05210  Colorectal cancer
mlx05212  Pancreatic cancer
mlx05220  Chronic myeloid leukemia
mlx05225  Hepatocellular carcinoma
mlx05226  Gastric cancer
mlx05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118017899 (TGFBR1)
   04350 TGF-beta signaling pathway
    118017899 (TGFBR1)
   04390 Hippo signaling pathway
    118017899 (TGFBR1)
   04371 Apelin signaling pathway
    118017899 (TGFBR1)
   04068 FoxO signaling pathway
    118017899 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    118017899 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    118017899 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    118017899 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    118017899 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    118017899 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    118017899 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    118017899 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    118017899 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    118017899 (TGFBR1)
   05212 Pancreatic cancer
    118017899 (TGFBR1)
   05225 Hepatocellular carcinoma
    118017899 (TGFBR1)
   05226 Gastric cancer
    118017899 (TGFBR1)
   05220 Chronic myeloid leukemia
    118017899 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118017899 (TGFBR1)
   05161 Hepatitis B
    118017899 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    118017899 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    118017899 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    118017899 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:mlx01001]
    118017899 (TGFBR1)
Enzymes [BR:mlx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     118017899 (TGFBR1)
Protein kinases [BR:mlx01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   118017899 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2 Haspin_kinase
Other DBs
NCBI-GeneID: 118017899
NCBI-ProteinID: XP_034872108
LinkDB
Position
Unknown
AA seq 503 aa
MEAAAAAPRPRLLLLVLAAAATLVPGTTALQCFCHLCTKDNFTCVTDGLCFVSVTETTDK
VIHNSMCIAEIDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGSFSGKPSSG
LGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq 1512 nt   +upstreamnt  +downstreamnt
atggaggcggcggccgctgctccgcgtccccggctgctcctcctcgtgttggcggcggcg
gcgacgctggtcccggggacgacggcattacagtgtttctgccacctttgtacaaaagac
aattttacttgtgtgacagatgggctctgctttgtctctgtcacagagaccacagacaaa
gttatacacaatagcatgtgtatagctgaaattgacctaattcctcgagacagaccattt
gtatgtgcaccatcttcaaaaactgggtctgttactacaacctattgctgcaaccaggac
cattgcaataaaatagaactcccaactgttggctctttttcaggaaagccatcatctggc
cttggtcccgtcgaactggcagctgtcattgctggaccagtctgctttgtctgcatctca
ctcatgttgatggtttatatctgccataaccgtactgtcattcaccatcgcgtgccaaat
gaagaggatccttccttagatcgcccttttatttcagagggcactacattaaaagattta
atatatgatatgacgacatcaggttctggatcaggtttacctctgctcgttcagagaaca
attgcaagaactattgtgttacaagaaagtattggcaaaggtcgatttggagaagtttgg
cgaggaaagtggagaggagaagaagttgctgttaaaatattctcctctagagaagagcgc
tcatggttccgtgaggcagagatttatcagactgtaatgttacgtcatgaaaacatcttg
ggatttatagcagcagacaataaagataatggcacatggactcagctctggttggtgtca
gattaccatgagcatggatccctttttgattatttgaacagatatacagttactgtggaa
ggaatgataaaacttgctttgtccacagcaagtggacttgcccatctccacatggagatt
gttggtacccaagggaagccagccattgctcatagagatttgaaatccaagaatatcttg
gtaaagaagaatggaacttgctgtattgcagacttaggactggcagtgagacacgattca
gccacagatacaattgatattgctccaaatcacagagtgggaacaaaaaggtacatggcc
cctgaagttctagatgattccataaatatgaaacactttgaatccttcaaacgtgccgac
atctatgcaatgggcttagtattctgggaaatagctcgacgatgttccattggtggaatt
catgaagattaccagctgccttattatgatcttgtaccttctgatccatcagttgaagaa
atgagaaaagttgtttgtgaacagaagttaaggccaaatattccaaacagatggcagagt
tgtgaagctttgagagtaatggctaaaattatgagagaatgttggtatgccaatggagca
gcgaggcttacggctttgcgtattaagaaaacattgtcacaactcagtcaacaggaaggc
atcaaaatgtag

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