Mirounga leonina (Southern elephant seal): 118018354
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Entry
118018354 CDS
T07472
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx03030
DNA replication
mlx03410
Base excision repair
mlx03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
118018354 (POLE)
03410 Base excision repair
118018354 (POLE)
03420 Nucleotide excision repair
118018354 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlx03032
]
118018354 (POLE)
03400 DNA repair and recombination proteins [BR:
mlx03400
]
118018354 (POLE)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
118018354 (POLE)
DNA replication proteins [BR:
mlx03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
118018354 (POLE)
DNA repair and recombination proteins [BR:
mlx03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
118018354 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
CTNNB1_binding
Motif
Other DBs
NCBI-GeneID:
118018354
NCBI-ProteinID:
XP_034872671
LinkDB
All DBs
Position
Unknown
AA seq
2281 aa
AA seq
DB search
MVLRNSGRRRAEPGPDGEASRDDGPSSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
GWLINMHPTEVLDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SKKFQGKIAKIETVPKEDLDLPNHLVGLKRNYIKLSFNTVEDLVRVRKDVSPAVKKNREQ
GHAHDAYTAMLSCVLQGGSVVIDEEEASKKVTDQLDNIVDMREYDVPYHIRLSIDLKIHV
AHWYNVRYRGSAFPVEIARRDDLVERPDPVVLAFDIETTKLPLKFPDPETDQIMMISYMI
DGQGYLITNREIVSEDVEDFEFTPKPEYEGPFCVFNEPDEVHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAVHGLNMYQEIGFQKDSQGEYKASQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDAETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTMRHAIEEEEKVPMEQVTNFQEVC
DQIKTKLTSLKDVPNRIECPLIYHLDVGAMYPNIILTNRLQPSAVVDEATCAACDFNKPG
ADCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLTAEGPARAFHELSREEQAKYEK
RRLSDYCRKAYKKIHVTRVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAMELGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRRGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVIKTTSVKKPKVTISYPGAMLNIM
VKEGFTNDQYQELTEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEIKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPMVRKHFLRKWLKSSSLQDFDIRTILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVCKQKKISELFVLEGRRQVGTAQA
PESTQSLGASDMEDFGLVKPPHSAVPVATKRKRVLWESQEESQDLELTVPWQEILGQPPA
LGTTQEEWLVWLRFHKKKWQLQARQRLARKKRRRLEVAEGNPLPGAIRDRPATGLGSFLR
RTARSVLDLPWQIVQISETSQAGLFRLWAVISSDLYCIRLNIPRVFYVNQRVAKAEEGPS
YRKVSRVLPRSNMVYNLYEYSVPEDMYQEHINEINTELSAPDIEGVYETQVPLLFRALVQ
LGCVCVVNKPPTRHLSGWEAETFALEHLEMRSLAQFSYLDPGSIRHIYLYHHAQGHKALF
GLFVPSQRRASVFVLDTVRSNQMPSLSALYSAEHSLLMEKVGPELLPPSKHTFEVRAETD
MKTICRAIQRFLLAYKEERRGPTLIAVQSNWELKRLAGEVPVLEEFPLVPVRVADKISYG
VLDWQRLGGRRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFLARHLQRH
SHLLWLSPTSRPDLGGKEADDNRLVMEFDDQASVEINCPGCYSTVCVELDIQNLAVNTIL
QSHHINDMEGADSVGISFDVIQQASLEDMITGNQAASTLASYDETALCSSTFRILKSMVV
GWVKEITHYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
SSVIYANFNRIILCTKKRRIEDAIAYVEYITSSIHSKEIFHSLTISFSRCWEFLLWMDPS
NYGGIKGNVPSRIHCGQRDSPKEGREEEEEEEEEEEEEEDAGALEPDVEDMLENNWNIVQ
FLPQTASCQSYFLMIVSAYVVAVYHSMKEELRRSAPGATPLRRRGPSQLSQDAPAASALP
GMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSAELSSMFPVLPGSHLLLTNPALEFI
KYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCRSYVLPEVICRSCNFCR
DLDLCRESSFSQDGALLAQWLCSNCQIAYDTSVIEMALVEALQKKVMAFTLQDLICLKCR
GVKETNMPVYCHCAGGFALTIHTKVFMEQIGIFRNIAQHYGMSYLMETLEWLLQKNPQLG
H
NT seq
6846 nt
NT seq
+upstream
nt +downstream
nt
atggttctgaggaacagcgggcggcggcgcgcggagccgggcccggacggcgaggccagc
cgggatgatggcccctcttcctctgtctcggcacttaagcgcctggaacgcagtcagtgg
acagataagatggatttgcggtttggttttgagagactcaaggagcctggtgagaagaca
ggctggctcatcaacatgcaccctactgaggttttagatgaagacaaacgcttagtcagt
gcagtggattactactttattcaagatgatgggagcagatttaaggtggccttgccctac
aagccgtatttctacattgcaaccagaaagggttgtgaacgagaagtttcatcttttctc
tccaagaagtttcagggtaaaattgctaaaatagagactgtccccaaagaggatctggac
ttgccaaatcacttggtgggtttgaagcgaaattacattaagctatccttcaacaccgtg
gaggatcttgtcagagtgaggaaggatgtctcccctgccgtgaagaagaaccgggagcag
ggccatgcccatgatgcctacacagctatgctctcctgtgttctgcaagggggcagtgtg
gttattgatgaagaggaagcctctaagaaggtcaccgaccagttggataacattgtggac
atgcgggagtatgatgtgccctaccacatccgcctctccattgacctgaagatccatgtg
gctcattggtacaatgtcagataccgaggaagtgcctttcctgtggaaatcgcccgacga
gatgaccttgttgaacgacccgaccctgtggtattggcatttgacatcgagacgaccaaa
ctgcccctcaagtttcccgaccctgagactgaccagattatgatgatttcttatatgatc
gatggtcagggctacctcatcaccaacagggagatcgtttcagaagatgttgaagatttc
gagttcacccccaagccagagtatgaaggacctttttgtgtcttcaatgaacccgatgag
gttcatctaatccagagatggtttgaacatgtccaggagaccaaacccaccatcatggtc
acctacaatggtgacttttttgactggccgtttgtggaggccagagcagcggtccacgga
ttgaacatgtaccaggagatagggttccagaaggacagccagggggagtacaaggcctcc
cagtgcatccacatggactgtctcaggtgggtgaagagggacagttaccttcctgtgggc
agccataacctcaaggcggctgccaaagccaagctgggctacgaccctgtggagctggac
cccgaggacatgtgccggatggccactgagcagccccagactctggccacgtactcggtc
tcagatgcagtggccacgtactacctgtacatgaaatatgtccacccctttatattcgcc
ctctgcaccattatccccatggagcctgatgaggtgctgcggaagggctccgggacgctg
tgtgaggccctgttgatggtgcaggccttccatgccaacatcatcttccccaacaagcag
gagcaggagtttaacaagctcacagatgacggtcacgtgctggatgccgagacctatgtg
ggtggccacgtggaggcccttgagtcaggcgtgtttcgcagtgacatcccctgcaggttc
aggatgaatcctgctgcctttgacttcctgctgcagcgggtggagaaaaccatgcgtcat
gccatcgaggaagaggagaaggtgcccatggagcaggtcaccaatttccaagaggtgtgt
gatcagattaagaccaagctcacctccctgaaagatgttccaaacagaatagagtgtccc
cttatctaccacctggacgtgggggccatgtaccccaacatcatcctgacaaaccgcctg
cagccctctgccgtggtggatgaggccacgtgtgctgcctgtgacttcaacaagccggga
gcagactgccagaggaagatggcctggcagtggaggggcgagttcatgccagccagccgc
agcgagtaccatcggatccagcaccagctggagtcggagaagttccctcccttgactgca
gagggcccagcccgggcctttcacgagctgtcccgcgaggagcaggctaaatatgagaag
cggaggctgtcagattactgccggaaggcgtacaagaagatccatgtgaccagggtggag
gagcgcctcaccaccatctgccagcgggagaactccttctatgtggacacggtgcgtgcc
ttccgagacaggcggtatgagttcaaaggtcttcacaaggtgtggaaaaagaagctctcc
gcggccatggagctgggcgacgcagcggaagtgaagcgctgcaagaacatggaggtcctg
tacgactccctgcagctggcgcacaagtgcatcctcaactccttctacggctacgtcatg
cgcaggggggctcgctggtactccatggagatggcaggcatcgtctgcttcacgggggcc
aacatcatcacccaggcacgggagctgattgagcagatcgggaggcccttggagctggac
acggatggaatatggtgcgtcctgcccaacagcttccctgaaaactttgtcatcaaaacg
accagtgtaaaaaagcccaaggtgaccatttcctatcctggggccatgttaaacatcatg
gtcaaggaaggcttcaccaacgatcagtaccaggagctgactgagccatcctcactcacc
tatgtcacccgctcagagaacagcatctttttcgaggttgacgggccctacctcgccatg
atccttccagcctccaaggaagaaggcaagaaactgaagaagagatacgccgtctttaat
gaggacggttccctggctgagctaaagggcttcgagatcaaacgccgaggggagctgcaa
ctgattaagatcttccagtcctcggtgttcgaggccttcctcaagggcagcacgctagaa
gaagtgtatggctctgttgccaaggtggctgattactggctggatgtgctgtacagtaag
gcagctaacatgcccgattctgagctgtttgagctgatctctgagaaccgctccatgtct
cggaagctggaagattatggggagcagaagtccacgtctatcagcaccgccaagcgcctg
gctgagttcctgggagatcagatggtgaaggacgcggggctgagctgccgctacatcatc
tcgcggaagcctgaggggtctcctgttacagagagggctatcccgcttgccattttccag
gcagagcccatggtgaggaagcactttctccggaaatggcttaagagttcttccctccaa
gattttgatattcggacgattctggattgggactactacatcgagcgtctggggagtgcc
atacagaagatcatcacaatccctgcggctctgcagcaggtgaagaacccagtgccacgc
gtcaagcaccctgactggctgcacaagaaacttttggagaagaatgatgtctgcaagcag
aagaagatcagtgagctctttgtcctcgagggcaggagacaggtgggcacagcccaggct
ccagaaagcacgcagagccttggtgcttctgacatggaggattttggccttgtgaagcca
ccgcactcggcagttcctgttgccactaagaggaagcgtgtcctctgggagagccaggag
gagtcgcaggacctggaactgacggtaccctggcaggaaatcctggggcagcccccggcc
ctcggaaccacccaggaagagtggctggtctggctccggttccataagaagaagtggcag
ttgcaggcccggcagcgcctggcccgcaagaagaggcggcgtctggaggtggcagaaggc
aaccctctgcccggggccatccgagacaggcccgccaccgggttggggagcttcttgcga
aggaccgcccgtagcgtcttggaccttccgtggcagattgtgcagatcagtgagaccagc
caggcgggtctgttcaggctgtgggctgttatcagcagtgacttgtactgcatcaggctg
aacatcccccgtgtgttctatgtcaaccagcgggtggctaaagccgaggaggggccttca
tatcgcaaggtcagccgtgtccttccgcgctccaacatggtctacaatctctatgagtac
tcggtgcccgaagacatgtaccaggagcacatcaacgagatcaacactgagttgtcggcc
ccagacattgagggcgtgtatgagactcaggtcccgttactgttccgggccctggtgcag
ctgggctgtgtgtgtgtggtcaataaaccgccgacgaggcatctttcaggctgggaggca
gaaaccttcgctctcgagcacctggagatgcgctctctggcccagttcagctacctggac
ccagggagcatccgccacatctacctgtatcatcacgcccagggccataaagcactcttc
ggcttgttcgtgccctcccagcgcagagcgtctgtgtttgtgttggacaccgtgcgaagc
aaccaaatgcccagcctcagtgctctgtactccgccgagcacagcctcctgatggagaaa
gtgggtcccgagctcctgcctccgtccaaacacactttcgaagttcgggccgaaacggac
atgaagaccatctgcagggccatccagcgcttcttgctggcctacaaagaggagcgccgt
gggcccacactcatcgctgttcagtccaactgggagctgaagaggctggctggcgaggtc
cccgttctggaggagttcccgctggtgcctgtccgcgtggccgataagatcagctatggc
gtcctggactggcagcgccttggaggccggcgcatgatccgccactacctcaacctggac
acctgtctgtcacaggccttcgagatgagcaggtacttccacatccccattggtaatctg
cctgaggacatctccacctttggctccgacctcttcttagcccgccatctccagcgccac
agccacctgctctggctgtcccctacctcacgccctgacctgggtggcaaggaggctgat
gacaatcgcctcgtcatggagttcgatgaccaggccagtgtggagatcaactgtccaggc
tgctactccacggtgtgcgtggagctggacatccagaacctggccgtcaataccatcctg
cagtcccaccatatcaatgacatggaaggggccgacagcgtgggcatcagcttcgatgtg
atccagcaggcctccctggaggacatgatcaccggcaatcaggccgccagcaccctggcc
agctacgacgagacagcgctctgctccagcaccttcaggatcctgaagagcatggtggtg
ggctgggtgaaagagatcacacactaccacaacatctatgctgacaaccaggtgatgcac
ttttaccgctggctgcggtccccatcctcgctgctccatgaccctgctctgcaccgcaca
ctccacaacatgatgaagaagctctttctgcagctcatcgccgagttcaagcgcttgggg
tcctctgtcatctatgccaacttcaaccgcatcatcctctgcacgaaaaagcggcggatt
gaagatgccattgcctacgtggagtacatcaccagcagcatccattctaaagagatcttc
cattccttgacaatttctttctctcggtgctgggaatttcttctctggatggatccctcc
aactacggtggaatcaaaggaaacgttccatctcgtattcactgtggacagcgagactcc
ccaaaagagggcagagaggaggaggaggaggaggaggaggaggaggaggaggaggaggat
gcaggagcactggagcctgacgtggaggacatgctggaaaacaactggaacatcgtgcag
ttcctgccacagacagcctcgtgccagagctacttcctcatgatcgtgtcagcgtacgtc
gtggccgtgtaccacagcatgaaggaagagctgcggcgcagcgccccgggggccacgccg
ctgagacgccgggggcccagccagctgtcgcaggacgccccggcagccagcgcccttcct
ggaatgatcaccttctcgcaagactatgtggccaacgagctcacacagagcttcttcacc
atcactcagaagattcagaagaaggtcacgggctcgcggaactcggccgagctgtccagc
atgtttccggtgctcccgggttcccacctgctgctcaccaacccggcgctggagttcatc
aagtacgtgtgcaaggttctgtctctggacacgaacatcacaaaccaggtgaacaagttg
aaccgggacctgcttcgcctggtggacgtgggcgagttctcggaggaggcccagttccga
gacccctgtcgttcctacgtgcttcctgaggtcatatgccgcagctgtaacttctgccgg
gacctggacctgtgcagagaatcctccttctctcaggacggggctttgctggctcagtgg
ctctgctccaactgtcagattgcctatgacacatcagtcatcgagatggctctggtggaa
gccctgcagaagaaagtgatggccttcaccctgcaggacctgatctgcctgaagtgccgg
ggcgtgaaggagaccaacatgcccgtgtactgccactgtgcggggggctttgccctcacc
atccacaccaaggtcttcatggagcagattggaatcttccggaacattgcccagcactat
ggcatgtcgtacctcatggagaccctggagtggctgctgcagaagaaccctcagctgggc
cattag
DBGET
integrated database retrieval system
