Mirounga leonina (Southern elephant seal): 118018451
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Entry
118018451 CDS
T07472
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04148
Efferocytosis
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04380
Osteoclast differentiation
mlx04919
Thyroid hormone signaling pathway
mlx04972
Pancreatic secretion
mlx05010
Alzheimer disease
mlx05017
Spinocerebellar ataxia
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
mlx05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
118018451 (ATP2A2)
04024 cAMP signaling pathway
118018451 (ATP2A2)
04022 cGMP-PKG signaling pathway
118018451 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118018451 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118018451 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
118018451 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
118018451 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
118018451 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
118018451 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118018451 (ATP2A2)
05017 Spinocerebellar ataxia
118018451 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
118018451 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118018451 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
118018451 (ATP2A2)
05414 Dilated cardiomyopathy
118018451 (ATP2A2)
05415 Diabetic cardiomyopathy
118018451 (ATP2A2)
Enzymes [BR:
mlx01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
118018451 (ATP2A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
118018451
NCBI-ProteinID:
XP_034872871
LinkDB
All DBs
Position
Unknown
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDGCSLNEFTITGSTYAPLGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKVERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFRQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaggcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtccagcggatt
aaagctaaagacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtccattctc
acaggtgagtctgtatctgtcatcaagcacactgaccccgtcccagacccacgggctgtc
aatcaagataaaaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacagaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacccccctccagcagaaactagacgagtttggggaacagctt
tccaaagtcatctccctgatttgcattgcagtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggcgctatttactacttcaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccttctgtggaa
acccttggttgtacttccgttatctgctcagacaagactggtacactgacgacgaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatggttgttcccttaat
gagtttaccattaccggatcaacatacgcccctcttggagaagtgcataaagatgataag
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcgttggattacaatgaggcgaagggtgtgtatgaaaaagttggagaagct
acggagactgctcttacctgcctagtagagaagatgaacgtatttgataccgaattgaag
ggtctttctaaagtagagcgagcaaatgcctgcaactcggtcattaagcagttgatgaaa
aaggaatttactctggagttttcacgtgatagaaaatcgatgtcagtttattgtacacca
aacaaaccaagccggacgtcgatgagcaaaatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaagttcctatgaccccaggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagtggcagcgacacgctgaggtgc
ctggctctggccactcacgacaacccactgagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaatctgactttcgttggctgcgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaggcaggcatccgggtt
atcatgatcactggggacaacaagggcactgctgtggccatctgtcggcgtattggcatc
ttcaggcaggatgaggatgtgacgtcgaaagcttttacgggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgtttgaatgcccgatgtttcgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagataacagctatgact
ggggacggcgtgaatgatgctcctgccctgaagaaatcggagatcggcattgccatgggc
tctggcactgcagtggctaaaacggcgtctgagatggtcctggctgacgacaacttctcc
accattgtggctgcggtggaggaggggcgggccatctacaacaatatgaagcagtttatc
cgctacctcatctcgtcgaatgtgggggaagttgtctgtatcttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcccgccactgccctggggttcaaccctcccgatctggacatcatgaataaaccaccc
cggaacccgaaggaacccctgatcagcggatggctctttttccgttatctggccattggc
tgttacgttggtgctgctaccgtgggtgcggctgcgtggtggttcattgctgccgacgga
ggtccgagagtgactttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccgtacccgatgacaatggcgctg
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgccgccctgggagaacatctggctcgtgggctccatttgcctgtccatg
tcgctccacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggac
gagacactcaagttcgtggcccgcaactacctggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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