Mirounga leonina (Southern elephant seal): 118018518
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Entry
118018518 CDS
T07472
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00220
Arginine biosynthesis
mlx00330
Arginine and proline metabolism
mlx01100
Metabolic pathways
mlx04020
Calcium signaling pathway
mlx04081
Hormone signaling
mlx04145
Phagosome
mlx04371
Apelin signaling pathway
mlx04713
Circadian entrainment
mlx04730
Long-term depression
mlx04926
Relaxin signaling pathway
mlx04970
Salivary secretion
mlx05010
Alzheimer disease
mlx05014
Amyotrophic lateral sclerosis
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
mlx05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
118018518 (NOS1)
00330 Arginine and proline metabolism
118018518 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
118018518 (NOS1)
04020 Calcium signaling pathway
118018518 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
118018518 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
118018518 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
118018518 (NOS1)
09154 Digestive system
04970 Salivary secretion
118018518 (NOS1)
09156 Nervous system
04730 Long-term depression
118018518 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
118018518 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118018518 (NOS1)
05014 Amyotrophic lateral sclerosis
118018518 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
118018518 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118018518 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
118018518 (NOS1)
05414 Dilated cardiomyopathy
118018518 (NOS1)
05416 Viral myocarditis
118018518 (NOS1)
Enzymes [BR:
mlx01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
118018518 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
118018518
NCBI-ProteinID:
XP_034872983
LinkDB
All DBs
Position
Unknown
AA seq
1467 aa
AA seq
DB search
MENQVFNVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLGPPTAAVDLSHQSSASKEHTLPVDGTLGPGNGPQHAQDSGQGASALSNTNSLAR
RPPGQDPTKKSTGVALQDSQNSELLKEIEPVLSLLTSGSKGINGGGPSKAETKDAEVQVD
RGVDGKSHKPLPLSVENDRVFSDLWGKGNVPVILNNPYSEKEQPPASGKQSPTKNGSPSK
CPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHVCMSSIMLPSQQIRRPEDVRTKEQLFP
LAKEFIDQYYSSIKRFGSKAHTERLEEVNKEIETNGTYQLKDTELIYGAKHAWRNASRCV
GRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVWN
SQLIRYAGYKQPDGTILGDPANVEFTEICMKQGWKPPRGRFDVLPLLLQANGNDPELFQI
PPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVR
DYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSATE
SFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPEPWNTHVW
KGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCEI
FKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSMHE
ERKYPERLRFFPRKGPPLPQGDPGVRRLAAARDSQQRSYKVRFNSVSSYSDSHKSSGDGP
DLRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCG
QEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYMAEAPELTQ
GLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNRED
LVNALIERLEDAPPVNQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDITT
PPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPSTL
LLTQLSLLQPRYYSISSSPDMYPDEVHLTVAVVSYRTRDGEGPIHHGVCSSWLNQIQADE
VVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVFG
CRQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEHLAESVYRALKEQ
GGHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRLRDDNRYHEDIFGVTLRTY
EVTNRLRSESIAFIEESKKDTDEVFSS
NT seq
4404 nt
NT seq
+upstream
nt +downstream
nt
atggagaatcaggtgttcaatgttcagcagatccaacccaacgtcatttctgtccgcctc
ttcaagcgcaaggttgggggcctgggcttcctggtgaaggagcgggtgagcaagccaccc
gtgatcatctccgacctgatccgagggggtgccgcggagcagagcggcctcatccaggcc
ggcgacatcatcctcgccgtcaacggccagcccttggtggatctgagctatgacagtgcc
ctggaggtgctcaggggcattgcctctgagacccacgtggtcctcattctgaggggccct
gagggcttcaccactcacctggagaccaccttcactggggatgggacccccaagaccatc
cgggtgacacggcccctgggtccccccaccgcagctgtcgatctgtctcaccagtcatcg
gccagcaaagagcacacactgccagtggacgggaccctggggcctggcaatgggccccag
catgcccaagacagtgggcagggagccagcgcactctcgaataccaacagcctggctcgc
agaccccctggccaggaccctaccaagaaaagcaccggggtggctctccaggacagccag
aacagtgaattgctcaaagagatagagcctgtgctgagccttctcaccagtgggagcaaa
gggatcaatggagggggaccttccaaggcagagacaaaggatgcagaagtccaggtagac
agaggtgtggatggcaagtcacacaaaccactgcccctcagcgtggagaatgaccgagtc
ttcagtgacctgtgggggaagggcaatgtgcctgtcatcctcaacaacccgtattcagag
aaggagcagccccctgcctcgggaaaacagtctcccacaaagaatggcagcccctccaag
tgcccccgcttcctcaaggtcaagaactgggagaccgacgtggtcctcactgacaccctt
caccttaagagcaccctggaaacaggatgcactgagcacgtctgtatgagctccattatg
ctcccttctcagcaaatacgaaggcctgaagatgtccgcacaaaagaacagctcttccct
ctcgccaaagagttcattgatcagtactactcatcaattaaaagatttggctccaaagcc
cacacagagaggctggaagaggtgaacaaagagatcgaaaccaacggcacctaccagctc
aaagacactgagctcatctatggggcgaagcacgcctggcggaatgcatcccgctgcgtt
ggcaggatccagtggtccaagctgcaggtgttcgatgcccgcgactgcaccacggctcac
gggatgttcaactacatctgcaaccacatcaagtatgccaccaacaaagggaacctcagg
tcagccatcaccatatttccacagaggactgacggcaagcacgatttccgagtctggaac
tctcagctcatccgctacgccggctacaagcagcccgacggcaccatcctcggggaccca
gccaacgtggaattcacagagatctgcatgaagcagggctggaaacccccaaggggccgc
ttcgatgtcctgccactcctgctccaggctaacggcaacgaccctgagctcttccagatc
cctccagagctggtgttggaagtgcccatcaggcaccccaagtttgagtggtttaaggat
ctgggcctgaagtggtacggcctccctgctgtgtccaacatgctgctggagattggcggc
ctggagttcagcgcctgccccttcagcggctggtacatgggcacggagatcggcgtccgt
gactactgtgacaactctcgatacaacatcctggaggaagtggccaagaagatgaacttg
gacatgaggaagacgtcctccctgtggaaggaccaggcgctggtggaaatcaacattgct
gttctctacagcttccagagtgacaaagtgaccatcgttgaccaccactctgccaccgag
tccttcattaagcacatggagaatgaataccgctgccgggggggctgccccgcagattgg
gtgtggattgtgccccccatgtctggcagtatcaccccggtcttccaccaggagatgctc
aactaccggctcaccccctccttcgaataccagcctgagccttggaacacccacgtctgg
aagggtaccaatgggacccccacaaagcggcgagccatcggcttcaagaagctggcagaa
gctgtcaagttctcggccaagctcatggggcaggcaatggccaagagggtcaaggcaacc
atcctttatgctacagagacaggcaagtcgcaggcctatgctaaaaccttgtgcgagatc
ttcaaacacgccttcgatgccaaggtgatgtccatggaagaatatgacattgtacatctg
gaacatgaaactctggtcctggtggttaccagcacttttggcaatggagacccccctgag
aatggggagaaattcggctgtgctttgatggaaatgaggcaccccaactctatgcacgaa
gaaaggaagtacccggaacgcttgcgtttctttccccgtaaagggcctcccctcccccaa
ggtgacccaggagtccgccgtctggctgcagcccgtgacagccagcagaggagctacaag
gtccgattcaatagcgtttcctcatattctgactcccataaatcatcgggcgatgggcca
gacctcagagacaactttgagagtgccggacccctggcaaacgtgaggttctctgtcttt
ggccttggctcccgggcttaccctcatttctgcgcctttggacatgctgtggacaccctc
ttggaggagctgggaggagagaggatcctgaagatgagggaaggggatgagctttgtggg
caagaagaggctttcaggacctgggccaagaaggtctttaaggcagcctgcgatgtgttc
tgcgtgggagatgatgtcaacatcgagaaggccaacaactccctcatcagcaatgaccgc
agctggaaaaggaacaagttccgtctcacctacatggccgaagctccagagcttacgcaa
ggtctctccaatgtccacaaaaagcgggtctcagctgctcgactcctcagccgtcaaaac
cttcagagccctaaatccagccgatcaaccatcttcgtgcgtctgcacaccaacgggaat
caggagctgcaataccagcctggggaccacctgggtgtcttccctggcaaccgcgaggac
ctcgtgaacgccctgatcgagcggctggaggacgcacctccggtcaaccagctggtgaag
gtggagctgctagaggagcgaaacacggctttgggagtcatcagtaactggacagatgag
caccgcctcccgccctgcaccatcttccaggccttcaagtactacctggacatcaccacg
ccgccaacgccactgcagctgcagcagtttgcctctctggccaccagcgagaaagagaag
cagcgtctgctggtcctcagcaagggtttgcaggagtacgaagaatggaagtggggcaag
aaccccaccatcgtggaggtgctggaggagttcccatccatccagatgccctctaccctg
ctcctgacccagctgtccctgctgcagccccgttactactccatcagctcctccccagac
atgtaccccgacgaggtgcacctcaccgtggccgttgtctcctaccgcacccgagatgga
gaaggaccaattcaccacggtgtgtgctcctcctggcttaaccagatacaggctgacgaa
gtggtcccgtgtttcgtgagaggagcacccagcttccacctgccccgaaacccccaagtg
ccctgcatcctcgttggcccaggcaccggcatcgcccctttccgaagtttctggcagcaa
cggcaatttgacatccaacacaaaggaatgagcccctgccccatggtcctggtgttcggg
tgccggcaatccaagatagaccacatctacagggaggagactctacaagccaagaacaag
ggggtcttcagagaactgtacacggcctactcccgggagccagacaaaccaaagaagtac
gtgcaggacatcctgcaagagcatttggcagaatcagtgtaccgagccctgaaggagcaa
gggggccacatctatgtctgtggggacgtcaccatggctgccgatgtcctcaaagccatc
cagcgcatcatgacccagcaggggaaactctcagcggaggatgcaggcgtgttcatcagc
aggctgagggatgacaaccggtaccatgaggatattttcggggtcaccctgcgaacgtat
gaagtgaccaaccgccttagatctgaatccattgccttcattgaggagagcaaaaaagac
accgatgaggttttcagctcctaa
DBGET
integrated database retrieval system
