Mirounga leonina (Southern elephant seal): 118018619
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Entry
118018619 CDS
T07472
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00760
Nicotinate and nicotinamide metabolism
mlx01100
Metabolic pathways
mlx04068
FoxO signaling pathway
mlx04148
Efferocytosis
mlx04152
AMPK signaling pathway
mlx04211
Longevity regulating pathway
mlx04213
Longevity regulating pathway - multiple species
mlx04218
Cellular senescence
mlx04310
Wnt signaling pathway
mlx04922
Glucagon signaling pathway
mlx04936
Alcoholic liver disease
mlx05031
Amphetamine addiction
mlx05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
118018619
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
118018619
04068 FoxO signaling pathway
118018619
04152 AMPK signaling pathway
118018619
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118018619
09143 Cell growth and death
04218 Cellular senescence
118018619
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118018619
09149 Aging
04211 Longevity regulating pathway
118018619
04213 Longevity regulating pathway - multiple species
118018619
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
118018619
09165 Substance dependence
05031 Amphetamine addiction
118018619
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
118018619
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlx03036
]
118018619
03029 Mitochondrial biogenesis [BR:
mlx03029
]
118018619
Enzymes [BR:
mlx01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
118018619
Chromosome and associated proteins [BR:
mlx03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
118018619
Mitochondrial biogenesis [BR:
mlx03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
118018619
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
118018619
NCBI-ProteinID:
XP_034873172
LinkDB
All DBs
Position
Unknown
AA seq
744 aa
AA seq
DB search
MADEAALALQPGGSPSAVAAEREAASPPAGEPLRKRPRRDCPGLGRSPGEPGGAATEREV
PAATGGCPAAAAALWREAAAAGGEREAQAATAGEGDNGPGLQGLSREPPPADDFYDDDDD
DDEGEEEEEAAAATIGYRDDLLFDDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPY
TFVQQHLMIGTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIED
AVKLLQECKKIIVLTGAGVSVSCGIPDFRSRDGIYARLAIDFPDLPDPQAMFDIEYFRKD
PRPFFKFAKEIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGS
FATASCLICKYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRA
MKYDKDEVDLLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVI
INELCHRLGGEYAKLCCNPVKLSEITEKPPRTQKELAHLSDLPPTPLNISEDSSSPERTS
PPDSSAIVTLLDQATRSNVDDPGVSESKDCMEEKSQEGQNSTRNIESVTEQLESPDLKNV
GSNTGEKNERTSVADTVRKCWPPRLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSED
DVLSSSSCGSNSDSGTCQSPSLEEHLEDESEIEEFYNGLEDEADVNERAGGTGFGIGGGD
QEAVSEAICMKQEGTDINYPSNKS
NT seq
2235 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcccttcagcccggcggctccccctcggcggtggcggcc
gagagggaggccgcgtcgccgcccgccggggagcctctccgcaagaggccgcggagagac
tgtcccggcctggggcggagcccgggcgagcccggtggggcggccactgagcgtgaggtg
ccggcggcgaccgggggctgccccgcggcggccgcggcgctgtggcgggaggcggcggcg
gcgggcggggagcgggaggcccaggcggcgacggccggggaaggagacaatgggccgggc
ctacagggcctatcccgggagccgccgccggccgacgacttctacgacgacgacgacgac
gacgacgaaggcgaagaggaggaagaggcggcggcggcgacgattgggtaccgagatgac
cttctgtttgatgatgaaataatcaccaacggttttcattcctgtgaaagtgatgaggat
gatagagcctcacatgcaagctctagtgactggactccaaggccacggataggtccatat
acttttgttcagcaacatctcatgattggcacagatcctcgaacaattcttaaagattta
ctaccagaaacaattcctccacctgaattggatgatatgacactgtggcagattgttatt
aatatactttcagaaccaccaaaaaggaaaaaaagaaaagatattaatacaattgaagat
gctgtgaaattactgcaagagtgcaaaaaaataatagttctaactggagctggggtttct
gtttcttgtggaatacctgacttcaggtcaagagatggtatttatgctcgccttgcaata
gacttcccagaccttccagatcctcaagcaatgtttgatattgaatatttcagaaaagat
ccaagaccattcttcaagtttgcaaaggaaatatatcctggacagttccaaccatctctc
tgtcacaaattcatagccttgtcagataaagaaggaaaactacttcggaactatactcag
aacatagatacactggaacaggttgcaggaatccaaaggataattcagtgtcatggttcc
tttgcaacagcatcttgcttgatttgtaaatacaaagtagactgtgaagctgtacgagga
gatatttttaatcaggtggttcctcgttgtcctaggtgcccagctgatgagccacttgct
atcatgaaaccagagattgtcttttttggtgaaaatttaccagagcagtttcatagagcc
atgaaatatgacaaagatgaagttgatctcctcattgttattgggtcttccctgaaagta
agaccagtagcactaattccaagttccataccccatgaagtgcctcagatattaataaat
agagaacctttgcctcatctgcattttgatgtagagcttcttggagactgtgatgttata
ataaatgaattatgtcataggttaggtggtgaatatgccaaactttgctgcaaccctgta
aagctttcagaaattactgaaaaacctccacgaacacaaaaagagttggctcatttgtca
gatttgccacccacgcctcttaatatttcagaagactcaagttcaccagaaagaacttca
ccaccagattcttcagcgattgttacacttttagaccaagcaactaggagtaatgttgat
gatcctggtgtgtccgaatcaaaagattgtatggaagaaaaatcacaggaaggacagaat
tctactaggaacattgaaagtgttactgaacagttggaaagtccagatttgaagaacgtt
ggctctaacactggggaaaaaaatgaaagaacttcagttgctgacacggtgaggaagtgc
tggccacctagacttgcaaaggagcagattagcaaacggcttgatggtaaccagtatctg
tttttaccaccaaatcgttatattttccatggcgctgaggtatattcggactctgaagat
gacgtcttatcctctagttcttgtggcagtaacagtgatagtggaacatgccagagtcca
agtttagaagaacacttggaggatgaaagtgagattgaagaattttacaatggtttggaa
gatgaagctgatgttaatgagagagctggaggaactggatttggaattggtggaggtgat
caagaggcagtcagtgaagctatatgcatgaaacaggaaggaacagacattaactatcca
tcaaacaaatcataa
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