Mirounga leonina (Southern elephant seal): 118019366
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Entry
118019366 CDS
T07472
Symbol
PRKAA2
Name
(RefSeq) 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform X1
KO
K07198
5'-AMP-activated protein kinase, catalytic alpha subunit [EC:
2.7.11.31
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04068
FoxO signaling pathway
mlx04140
Autophagy - animal
mlx04150
mTOR signaling pathway
mlx04151
PI3K-Akt signaling pathway
mlx04152
AMPK signaling pathway
mlx04211
Longevity regulating pathway
mlx04213
Longevity regulating pathway - multiple species
mlx04371
Apelin signaling pathway
mlx04530
Tight junction
mlx04710
Circadian rhythm
mlx04714
Thermogenesis
mlx04910
Insulin signaling pathway
mlx04920
Adipocytokine signaling pathway
mlx04921
Oxytocin signaling pathway
mlx04922
Glucagon signaling pathway
mlx04931
Insulin resistance
mlx04932
Non-alcoholic fatty liver disease
mlx04936
Alcoholic liver disease
mlx05410
Hypertrophic cardiomyopathy
mlx05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
118019366 (PRKAA2)
04068 FoxO signaling pathway
118019366 (PRKAA2)
04151 PI3K-Akt signaling pathway
118019366 (PRKAA2)
04152 AMPK signaling pathway
118019366 (PRKAA2)
04150 mTOR signaling pathway
118019366 (PRKAA2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118019366 (PRKAA2)
09144 Cellular community - eukaryotes
04530 Tight junction
118019366 (PRKAA2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118019366 (PRKAA2)
04922 Glucagon signaling pathway
118019366 (PRKAA2)
04920 Adipocytokine signaling pathway
118019366 (PRKAA2)
04921 Oxytocin signaling pathway
118019366 (PRKAA2)
09149 Aging
04211 Longevity regulating pathway
118019366 (PRKAA2)
04213 Longevity regulating pathway - multiple species
118019366 (PRKAA2)
09159 Environmental adaptation
04710 Circadian rhythm
118019366 (PRKAA2)
04714 Thermogenesis
118019366 (PRKAA2)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
118019366 (PRKAA2)
05410 Hypertrophic cardiomyopathy
118019366 (PRKAA2)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
118019366 (PRKAA2)
04932 Non-alcoholic fatty liver disease
118019366 (PRKAA2)
04931 Insulin resistance
118019366 (PRKAA2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118019366 (PRKAA2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118019366 (PRKAA2)
03029 Mitochondrial biogenesis [BR:
mlx03029
]
118019366 (PRKAA2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
118019366 (PRKAA2)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: CAMK group
CAMKL family
118019366 (PRKAA2)
Membrane trafficking [BR:
mlx04131
]
Autophagy
Other autophagy associated proteins
Others
118019366 (PRKAA2)
Mitochondrial biogenesis [BR:
mlx03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
118019366 (PRKAA2)
Mitophagy factors
Other mitophagy factors
118019366 (PRKAA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
AMPK_alpha_AID
AdenylateSensor
Kinase-like
ABC1
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
118019366
NCBI-ProteinID:
XP_034874353
LinkDB
All DBs
Position
Unknown
AA seq
552 aa
AA seq
DB search
MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGK
IKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEVEARRLF
QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPTGSFMDDSTMHIP
PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
SGSSTPQRSCSAAGLHRPRSSFDCVTAESHSLPGSLPGSLTGSTLSSVPPRLGSHTMDFF
EMCASLITTLAH
NT seq
1659 nt
NT seq
+upstream
nt +downstream
nt
atggctgagaagcagaagcacgacgggcgggtgaagatcggacactacgtgttgggcgac
acgctgggcgtcggcaccttcggcaaagtgaagattggagaacatcaattgacaggccat
aaagtggcagttaaaatcttaaatagacagaagattcgcagtttagatgttgttggaaaa
ataaaacgagaaattcaaaatctgaaactgtttcgtcatcctcatattatcaaactatac
caggtgatcagcactccaacagatttttttatggtaatggaatatgtgtctggtggtgaa
ttatttgactacatctgtaaacatggccgggttgaagaggtggaagcaaggcggctcttt
cagcagattctatcagctgtggattactgtcataggcatatggtggttcatcgagacctg
aaaccagagaatgtgctgttggatgctcacatgaatgccaagatagctgactttggattg
tctaatatgatgtcagatggtgaatttctgagaactagttgtggatctccaaattatgca
gcacctgaagtcatctcaggcagattgtatgcaggtcctgaagttgatatttggagctgt
ggtgttattttgtatgcccttctttgtggcaccctcccatttgatgatgagcatgtacct
acgttatttaagaagatccgagggggtgttttttatatcccagaatatctcaatcgttct
gttgccactctcttgatgcatatgctgcaggttgaccccctgaaacgagcgaccatcaaa
gatataagagagcatgaatggtttaaacaagatttgcccagttacttatttcctgaagac
ccctcctatgatgctaacgtcattgatgatgaggctgtgaaagaagtgtgtgaaaaattt
gagtgtacagaatcagaagtaatgaacagtttatatagtggtgaccctcaagaccagctt
gcagtggcttatcatcttatcattgacaatcggagaataatgaaccaagccagtgagttc
tacctcgcctctagtcccccaactggttcttttatggatgatagtaccatgcatattccc
ccaggcctgaaacctcatccagaaaggatgccacctcttatagcagacagccctaaagca
agatgtccgttggatgcactgaatacaactaagcccaaatctttagctgtgaaaaaagcc
aaatggcatcttggaatcagaagtcaaagcaaaccgtatgacattatggctgaagtctac
cgagctatgaagcagctggattttgaatggaaggtagtgaatgcataccatcttcgtgta
agaagaaaaaatccagtgactggcaattatgtgaaaatgagcttacaactttacctggtt
gacaatagaagctatcttttggactttaaaagcattgatgatgaggtggtggagcagagg
tcgggttcttcaacgcctcagcgttcctgttctgctgctggcttacatagaccaagatca
agttttgattgtgtaacagcggagagccattcacttcctggctctctccctggctccttg
accggaagcacattgtcttcagttccaccccgcctaggcagtcacaccatggattttttt
gaaatgtgtgccagtctgatcactactttagcccattga
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