KEGG   Mirounga leonina (Southern elephant seal): 118022080
Entry
118022080         CDS       T07472                                 
Symbol
PPP3CC
Name
(RefSeq) serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X1
  KO
K04348  serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]
Organism
mlx  Mirounga leonina (Southern elephant seal)
Pathway
mlx04010  MAPK signaling pathway
mlx04020  Calcium signaling pathway
mlx04022  cGMP-PKG signaling pathway
mlx04114  Oocyte meiosis
mlx04218  Cellular senescence
mlx04310  Wnt signaling pathway
mlx04360  Axon guidance
mlx04370  VEGF signaling pathway
mlx04380  Osteoclast differentiation
mlx04625  C-type lectin receptor signaling pathway
mlx04650  Natural killer cell mediated cytotoxicity
mlx04658  Th1 and Th2 cell differentiation
mlx04659  Th17 cell differentiation
mlx04660  T cell receptor signaling pathway
mlx04662  B cell receptor signaling pathway
mlx04720  Long-term potentiation
mlx04724  Glutamatergic synapse
mlx04728  Dopaminergic synapse
mlx04921  Oxytocin signaling pathway
mlx04922  Glucagon signaling pathway
mlx04924  Renin secretion
mlx05010  Alzheimer disease
mlx05014  Amyotrophic lateral sclerosis
mlx05020  Prion disease
mlx05022  Pathways of neurodegeneration - multiple diseases
mlx05031  Amphetamine addiction
mlx05152  Tuberculosis
mlx05163  Human cytomegalovirus infection
mlx05166  Human T-cell leukemia virus 1 infection
mlx05167  Kaposi sarcoma-associated herpesvirus infection
mlx05170  Human immunodeficiency virus 1 infection
mlx05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mlx05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mlx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    118022080 (PPP3CC)
   04310 Wnt signaling pathway
    118022080 (PPP3CC)
   04370 VEGF signaling pathway
    118022080 (PPP3CC)
   04020 Calcium signaling pathway
    118022080 (PPP3CC)
   04022 cGMP-PKG signaling pathway
    118022080 (PPP3CC)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    118022080 (PPP3CC)
   04218 Cellular senescence
    118022080 (PPP3CC)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    118022080 (PPP3CC)
   04650 Natural killer cell mediated cytotoxicity
    118022080 (PPP3CC)
   04660 T cell receptor signaling pathway
    118022080 (PPP3CC)
   04658 Th1 and Th2 cell differentiation
    118022080 (PPP3CC)
   04659 Th17 cell differentiation
    118022080 (PPP3CC)
   04662 B cell receptor signaling pathway
    118022080 (PPP3CC)
  09152 Endocrine system
   04922 Glucagon signaling pathway
    118022080 (PPP3CC)
   04921 Oxytocin signaling pathway
    118022080 (PPP3CC)
   04924 Renin secretion
    118022080 (PPP3CC)
  09156 Nervous system
   04724 Glutamatergic synapse
    118022080 (PPP3CC)
   04728 Dopaminergic synapse
    118022080 (PPP3CC)
   04720 Long-term potentiation
    118022080 (PPP3CC)
  09158 Development and regeneration
   04360 Axon guidance
    118022080 (PPP3CC)
   04380 Osteoclast differentiation
    118022080 (PPP3CC)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    118022080 (PPP3CC)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    118022080 (PPP3CC)
   05170 Human immunodeficiency virus 1 infection
    118022080 (PPP3CC)
   05163 Human cytomegalovirus infection
    118022080 (PPP3CC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    118022080 (PPP3CC)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    118022080 (PPP3CC)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    118022080 (PPP3CC)
   05014 Amyotrophic lateral sclerosis
    118022080 (PPP3CC)
   05020 Prion disease
    118022080 (PPP3CC)
   05022 Pathways of neurodegeneration - multiple diseases
    118022080 (PPP3CC)
  09165 Substance dependence
   05031 Amphetamine addiction
    118022080 (PPP3CC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    118022080 (PPP3CC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mlx01009]
    118022080 (PPP3CC)
Enzymes [BR:mlx01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     118022080 (PPP3CC)
Protein phosphatases and associated proteins [BR:mlx01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Catalytic subunits
     118022080 (PPP3CC)
SSDB
Motif
Pfam: Metallophos DUF5378 DUF7084
Other DBs
NCBI-GeneID: 118022080
NCBI-ProteinID: XP_034878422
LinkDB
Position
Unknown
AA seq 534 aa
MSGRNLHLSTTERVIKAVPFPPTQRLTLKEVFENGKPKIDVLKNHLVKEGRLEEEVALKI
INDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRGY
FSIECVLFLWSLKINHPKTVFLLRGNHECRHLTEYFTFKQECRIKYSEQVYDACMETFDC
LPLAALLNQQFLCVHGGMSPEITSLDDIKKLDRFKEPPAFGPVCDLLWSDPSEDYGNEKT
LEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLIT
IFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCSPHPYWLPNFMDVFTWSLPFVGEKVTEM
LVNILNICSDDELISDDEIEDHYISSYRKGGTTVRKEIIKNKIRAIGKMARVFSILREES
ESVLTLKGLTPTGTLPLGVLSGGKQTIETATVEAVEAREAIRGFSLQHRIRSFEEARGLD
RINERMPPRKDSQYPDGPVKLVAPAQPNAVHRSNRGRRASNDAEPCCGTGGSKT
NT seq 1605 nt   +upstreamnt  +downstreamnt
atgtccgggaggaacctccacctctccaccaccgaacgcgtcatcaaagctgttcccttt
cctccaacccaacggcttactttgaaggaagtatttgagaatgggaaacctaaaattgat
gttttgaaaaaccatttggtgaaggaagggcgactggaagaggaagtagccttaaagata
atcaatgatggggctgccatcctgagacaagagaagactatgatagaagtagatgcacca
atcacagtgtgtggtgacattcatggacagttctttgacctgatgaagttgtttgaagtt
ggaggatcacctagtaacacacgctacctctttctgggtgactatgtggacagaggctat
ttcagtatagagtgtgtgctgtttttatggagtttaaagattaatcatcccaaaacagtg
tttttgcttcgaggaaatcatgaatgcagacatcttacagaatatttcaccttcaaacag
gaatgtcgaatcaaatattctgaacaggtgtatgatgcgtgtatggaaacatttgactgt
cttcctcttgctgccctcttaaaccagcagtttctgtgtgtacatggagggatgtcacct
gaaattactagtttagatgacattaagaaattagacaggtttaaagaacctccagccttt
gggccagtgtgtgacctgctttggtctgatccttcagaggattatggtaatgaaaagacc
ttggagcactatacccacaacactgtccgagggtgctcttatttttacagttaccctgca
gtttgtgaatttttacagaacaataatttgttatcaataatcagagcccacgaagcccag
gatgctgggtatcgaatgtacaggaagagccaaacaacaggctttccatcactcattaca
attttctctgcccccaattacctagatgtctataataataaagctgctgtgctaaaatat
gaaaacaatgtcatgaatatcaggcagtttaactgttctccacacccctactggcttcca
aactttatggacgttttcacatggtctttgccatttgttggggaaaaagtcacagagatg
ctggttaacattctcaacatatgctctgatgatgaattgatttccgatgatgaaattgaa
gatcactacatttcaagctatcggaaaggaggcactacagttcgaaaggagatcatcaag
aataaaatcagagccattgggaagatggcacgggtcttttcaattctgcgggaagagagt
gagagtgtgctgactctcaagggcctgactccaacagggacactccctctaggtgtcctc
tcaggaggaaagcagactattgagacagccacagtagaagcggtagaggcccgggaagcc
atcagagggttttcgcttcagcacaggatccggagttttgaagaagcccgaggtctggac
cgaattaacgaacggatgccaccccgaaaagacagccagtaccccgatgggccagtgaaa
ttggtggcccctgcacaacccaatgctgtgcacaggagcaacagggggagaagagccagt
aatgacgcagagccctgctgtggcacaggtggatccaaaacttaa

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