Mirounga leonina (Southern elephant seal): 118022694
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Entry
118022694 CDS
T07472
Symbol
ACTN4
Name
(RefSeq) alpha-actinin-4 isoform X1
KO
K05699
actinin alpha 1/4
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04510
Focal adhesion
mlx04517
IgSF CAM signaling
mlx04520
Adherens junction
mlx04530
Tight junction
mlx04670
Leukocyte transendothelial migration
mlx04810
Regulation of actin cytoskeleton
mlx05146
Amoebiasis
mlx05203
Viral carcinogenesis
mlx05322
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
118022694 (ACTN4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118022694 (ACTN4)
04520 Adherens junction
118022694 (ACTN4)
04530 Tight junction
118022694 (ACTN4)
09142 Cell motility
04810 Regulation of actin cytoskeleton
118022694 (ACTN4)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
118022694 (ACTN4)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
118022694 (ACTN4)
09174 Infectious disease: parasitic
05146 Amoebiasis
118022694 (ACTN4)
09163 Immune disease
05322 Systemic lupus erythematosus
118022694 (ACTN4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mlx04131
]
118022694 (ACTN4)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
mlx04812
]
118022694 (ACTN4)
04147 Exosome [BR:
mlx04147
]
118022694 (ACTN4)
Membrane trafficking [BR:
mlx04131
]
Exocytosis
Small GTPases and associated proteins
Rab associated proteins
118022694 (ACTN4)
Cytoskeleton proteins [BR:
mlx04812
]
Eukaryotic cytoskeleton proteins
Actin filaments / Microfilaments
Actin-binding proteins
Cross-linking proteins
118022694 (ACTN4)
Exosome [BR:
mlx04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
118022694 (ACTN4)
Exosomal proteins of colorectal cancer cells
118022694 (ACTN4)
Exosomal proteins of bladder cancer cells
118022694 (ACTN4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Spectrin
CH
EFhand_Ca_insen
EF-hand_1
EF-hand_6
EF-hand_7
XisI
Motif
Other DBs
NCBI-GeneID:
118022694
NCBI-ProteinID:
XP_034879324
LinkDB
All DBs
Position
Unknown
AA seq
911 aa
AA seq
DB search
MVDYHAANQSYQYGPNSGGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWC
NSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIA
SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPY
KNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKM
LDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYER
LASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTL
QTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQ
KASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQEL
NELDYYDSHNVNTRCQKICDQWDALGSLTQSRREALEKTEKQLETIDQLHLEYAKRAAPF
NNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAES
NHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNERLRRQFASQANI
VGPWIQTKMEEIGRISIEMNGTLEDQLNHLKRYERSIVDYKPNLDLLEQQHQLIQEALIF
DNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKD
HGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETT
DTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKS
FSTALYGESDL
NT seq
2736 nt
NT seq
+upstream
nt +downstream
nt
atggtggactaccacgcggcgaaccagtcgtaccagtacggccctaacagcgggggcaat
ggcgccggcggcgggggaagcatgggcgactacatggcccaggaggacgactgggaccgg
gacctgctcttggacccggcctgggagaagcagcagcgcaagacattcacagcctggtgc
aactcccaccttcggaaggccggcacgcagatcgagaacatcgacgaggactttcgagac
gggctcaagctcatgctccttctggaggtcatctcaggagagcggttacctaagccggag
cggggcaagatgagagtgcacaaaatcaacaatgtgaacaaagctctggacttcatcgcc
agcaaaggagtcaagctggtctccatcggggcggaagagattgtggacggcaatgcaaag
atgaccttgggaatgatctggaccatcatcctccggttcgccatccaggacatctctgtg
gaagagacctctgccaaggaagggctactcctgtggtgtcagaggaagactgccccatat
aagaacgtcaacgtgcagaacttccacatcagctggaaggacggtcttgccttcaatgca
ctgatccaccggcaccgaccagagctgatcgagtatgacaagctgagaaaggatgaccct
gtcaccaacctgaacaatgccttcgaagtggccgagaaatacctagacatccccaagatg
ttggatgcggaggacatcgtgaacacggcccggcccgacgagaaggccataatgacctat
gtgtccagcttctaccatgccttttcgggagcgcagaaggctgagaccgctgccaaccgg
atctgcaaggtgctggccgtcaaccaggagaatgagcacctcatggaagattatgagagg
ctggccagtgacctcctggagtggatccggcgcaccatcccctggctggaggatcgggtg
ccgcagaagaccatccaggagatgcagcagaagctggaggacttccgggactaccggcgc
gtccacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacgctg
cagacgaagctgcgcctcagcaaccggcccgccttcatgccctccgagggcaagatggtc
tcggacatcaacaacggctggcagcacctggagcaggccgagaagggctacgaggagtgg
ctgctgaacgagatccgcaggctggagcggctcgaccacctggcagagaagttccggcag
aaggcctccatccacgaggcctggactgacgggaaggaggccatgctgaagcaccgggac
tatgagacagccaccctgtcggacatcaaagccctcattcgcaagcacgaggcctttgag
agcgacctggccgcgcaccaggaccgcgtggagcagatcgccgcgattgctcaggagctc
aatgagctggactactatgactcgcacaacgtcaacacccgctgccagaagatctgcgac
cagtgggacgcccttggctctctgacccagagtcgcagggaagctctggagaaaacggag
aagcagctggagaccatcgaccagctgcacctggagtatgccaagcgggcggcgcccttc
aacaactggatggagagcgccatggaggacctccaggacatgttcatcgtccacaccatc
gaggagatcgagggcctgatttcagcccacgaccagttcaagtcgacgctgccagacgcc
gacagggagcgcgaggccatcctggccatccacaaggaggcccagagaatcgccgagagc
aaccacatcaaactgtcgggcagcaacccttacaccacggtcaccccgcagatcatcaac
tccaagtgggagaaggtgcagcagctggtgcccaagcgggaccacgcactcctggaggag
cagagcaagcagcagtccaacgagcgcctccgccgccagttcgccagccaggccaacatc
gtggggccctggatccagacgaagatggaggagatcgggcgcatctccattgagatgaac
gggaccctggaggaccagctgaaccacctgaagcggtacgagcgcagcatcgtggactat
aagccgaacctcgacctgcttgagcagcagcaccagctcatccaggaggccctcatcttc
gacaacaagcacaccaactacaccatggagcatatccgcgtgggctgggagcagctgctc
accaccatcgcccgcaccatcaatgaggtcgagaaccagatcctcacccgcgatgccaag
ggcatcagccaggagcagatgcaggagttccgggcgtccttcaaccactttgacaaggac
cacggcggggcgctggggccggaggagttcaaggcctgcctcatcagcctgggctacgac
gtggagaatgaccggcagggtgatgccgagttcaaccgcatcatgagcgtggttgacccc
aaccacagcggtctcgtgaccttccaagccttcattgacttcatgtcaagggagaccacc
gacacagacacggccgaccaggtcatcgcctccttcaaggtcctggcaggggacaagaac
ttcatcacggccgaggagctgcggagagagctgcccccggaccaggccgagtactgcatc
gctcgcatggcgccctaccagggccctgacgccgtgcccggcgccctcgactacaagtcc
ttctcgacagccctgtacggcgagagtgacctgtga
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