Mirounga leonina (Southern elephant seal): 118024846
Help
Entry
118024846 CDS
T07472
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01521
EGFR tyrosine kinase inhibitor resistance
mlx01522
Endocrine resistance
mlx01524
Platinum drug resistance
mlx04010
MAPK signaling pathway
mlx04012
ErbB signaling pathway
mlx04020
Calcium signaling pathway
mlx04066
HIF-1 signaling pathway
mlx04151
PI3K-Akt signaling pathway
mlx04510
Focal adhesion
mlx04520
Adherens junction
mlx04530
Tight junction
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
mlx05206
MicroRNAs in cancer
mlx05212
Pancreatic cancer
mlx05213
Endometrial cancer
mlx05215
Prostate cancer
mlx05219
Bladder cancer
mlx05223
Non-small cell lung cancer
mlx05224
Breast cancer
mlx05226
Gastric cancer
mlx05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118024846 (ERBB2)
04012 ErbB signaling pathway
118024846 (ERBB2)
04066 HIF-1 signaling pathway
118024846 (ERBB2)
04020 Calcium signaling pathway
118024846 (ERBB2)
04151 PI3K-Akt signaling pathway
118024846 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118024846 (ERBB2)
04520 Adherens junction
118024846 (ERBB2)
04530 Tight junction
118024846 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118024846 (ERBB2)
05206 MicroRNAs in cancer
118024846 (ERBB2)
05205 Proteoglycans in cancer
118024846 (ERBB2)
05230 Central carbon metabolism in cancer
118024846 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
118024846 (ERBB2)
05226 Gastric cancer
118024846 (ERBB2)
05219 Bladder cancer
118024846 (ERBB2)
05215 Prostate cancer
118024846 (ERBB2)
05213 Endometrial cancer
118024846 (ERBB2)
05224 Breast cancer
118024846 (ERBB2)
05223 Non-small cell lung cancer
118024846 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118024846 (ERBB2)
01524 Platinum drug resistance
118024846 (ERBB2)
01522 Endocrine resistance
118024846 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118024846 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mlx04147
]
118024846 (ERBB2)
04090 CD molecules [BR:
mlx04090
]
118024846 (ERBB2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118024846 (ERBB2)
Protein kinases [BR:
mlx01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
118024846 (ERBB2)
Exosome [BR:
mlx04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
118024846 (ERBB2)
CD molecules [BR:
mlx04090
]
Proteins
118024846 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
118024846
NCBI-ProteinID:
XP_034882920
LinkDB
All DBs
Position
Unknown
AA seq
1260 aa
AA seq
DB search
MELAAWCRWGLLLALLPCGAAGTQVCTGTDMKLQLPASPETHLDMLRHLYQACQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHSQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
EPPEGGASEAGAAPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDTNRSRACPPCSPACKDPHCWGASSGDCQSLTRTVCAGGCARCKGPKPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKVFGSLAFLPESFEGDPGSNTAPLQPEQLRVFEALEEITGYLYISAWPDSLP
NLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNARLCFIHTV
PWDQLFRNPHQALLHSANRPEAECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHSECRPQNGSVTCFGAEADQCVACAHYKDPPFCVARC
PSGVKPDLSFMPIWKFADEEGTCQPCPINCTHSCADLDERGCPAEQRASPVTSIIAAVVG
ILLAVVVGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGPAHHRHRSSSTRSGGGEVTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLHSLPPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVWPQPPSPLEGPLPPSRPAGATLERPKTLSPKTLSPGKNGVVKDVFAFGSAVENPE
YLAPRGRAPPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3783 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccctgcggagcc
gcgggcacccaagtgtgtaccggtacagacatgaagctgcagctcccagccagtcccgag
acgcacctggatatgctccgtcacctctaccaggcctgtcaagtggtgcagggtaacctg
gagctcacctacctgcctgccaatgccagcctgtccttcctgcaggatatccaggaggtg
cagggctacgtgctcattgctcacagccaagtgagacaggtcccgctgcagaggctccga
atcgtgcgaggcacccagctctttgaggacaactacgccctggccgtgctggacaatgga
gagccgcccgaggggggcgcctctgaggcaggggctgccccaggagggctgcgggagctg
cagcttcgaagcctcacagagatcctgaagggaggggtcttgattcagcggaacccacag
ctctgccaccaggacacgattttgtggaaggacatcttccacaagaacaaccagcttgcg
ctcatgctgatagacaccaaccgctctcgggcctgcccaccctgttctccagcttgtaaa
gacccccactgctggggagcaagttccggggactgtcagagcttgacgcgaacggtctgt
gccggaggctgtgcccgctgcaagggcccgaagcccactgactgctgccacgagcagtgt
gcagcgggttgcacaggccccaagcactcggactgcctggcctgccttcacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgaa
tccatgcccaaccccgagggccgatacaccttcggggccagctgtgtgaccgcctgtcca
tacaactacctatctacggacgtgggctcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacggctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctacggcctgggcatggagcacctgcgggaggtgagggcggtcaccagcgccaac
atccaagagtttgccggctgcaagaaggtctttgggagcctggcgtttctgccagagagc
tttgagggagacccaggctccaacactgcccccctccagcctgagcagctcagagtgttt
gaggctctggaggagatcacaggttacctgtatatctcagcgtggccagacagcctgcct
aacctcagtgtcttccagaacctgcgagtcatccggggacgagttctgcatgacggcgcc
tactcgctgaccctgcaagggctgggcatcagctggctggggctgcgctcactgcgggaa
ctgggcagtgggctggccctcatccaccacaacgcccgcctctgcttcatacacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctgcacagtgccaaccggccg
gaggccgagtgcgtgggcgagggcctggcctgctacccgctgtgcgcccatgggcactgc
tggggtccggggcccacccagtgcgtcaactgcagccaattccttcggggccaggagtgc
gtggaggaatgccgagtactgcaggggctaccccgggaatatgtgaaggacaggtactgt
ctgccgtgtcactccgagtgtcggccccagaacggctcagtgacctgctttggggcggag
gctgaccagtgtgtggcctgtgcccactacaaggaccctcccttctgcgtggctcgctgc
cccagtggtgtgaaacccgacctctccttcatgcccatttggaagttcgcagatgaggag
ggcacgtgccagccgtgtcccatcaactgcacccactcctgtgcggacctagacgagagg
ggctgccctgccgagcagagagccagccccgtgacatccatcattgctgctgtggtgggc
attctgctggctgtggtcgtggggctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccggaagtacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acgcctagcggagcgatgcccaaccaggctcagatgcggatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcttggatgaagcgtatgtgatggctggcgtgggctcccca
tatgtgtcccgccttctgggcatctgcctgacatccacggtgcagctggtaacacagctc
atgccctacggctgcctcttagaccatgtccgagagcaccgcgggcgcctaggctcccag
gacctgctgaactggtgtgtgcagatcgccaaggggatgagctacttggaggacgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggttgctggacattgacgagaccgagtaccacgcggat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
caccagagcgatgtgtggagctacggtgtgactgtgtgggaactgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccccatctgtaccattgacgtctacatgatcatggtcaaatgttggatg
atagactccgaatgtcgaccacggttccgggagctggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggttatccagaatgaagacttgggccccgccagcccgttg
gacagcaccttctaccgttcgctgctggaagatgatgacatgggggacctggtggatgct
gaggagtacctggtaccccagcaggggtttttctgtccagaccctgccccaggtgctggg
ggcccggcccaccacaggcaccgcagctcatccaccaggagtggcggtggtgaggtgaca
ctgggactggagccctccgaggaggagccccccaagtctccactggcaccctcagagggg
gctggctctgacgtgtttgatggcgacttgggaatgggggcagccaaggggctgcacagc
ctcccgccacaggaccccagtcctctacagcggtacagcgaggaccctacagtacccctg
ccccctgagactgatggctacgttgcccccctgacctgcagcccccagcctgaatatgtg
aatcagccagaggtttggccgcagcccccctcgcccctagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactttgtcccccaagactctctcccct
ggcaagaatggggttgttaaagacgtttttgcctttgggagtgctgtggagaaccctgag
tacttggcaccccggggcagggctccccctcagccccaccctcctccagccttcagccca
gcatttgacaacctctattactgggaccaggacccatcagagcggggctctccacccagc
acctttgaagggacccctacagcagaaaaccctgagtacctgggcctggacgtgccagtg
tga
DBGET
integrated database retrieval system
