Mirounga leonina (Southern elephant seal): 118024865
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Entry
118024865 CDS
T07472
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118024865 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mlx03032
]
118024865 (TOP2A)
03036 Chromosome and associated proteins [BR:
mlx03036
]
118024865 (TOP2A)
Enzymes [BR:
mlx01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
118024865 (TOP2A)
DNA replication proteins [BR:
mlx03032
]
Eukaryotic type
DNA Topoisomerases
118024865 (TOP2A)
Chromosome and associated proteins [BR:
mlx03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
118024865 (TOP2A)
Centrosome formation proteins
Centriole proteins
118024865 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
118024865
NCBI-ProteinID:
XP_034882958
LinkDB
All DBs
Position
Unknown
AA seq
1533 aa
AA seq
DB search
MEVSPLQPVNENMQISKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDIGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSSKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNSRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSNECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLTRLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDIREVVNNIRRLMDGEEPLPMLPSYKTFRGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQLKVPDEEENEESDNENEAEKSDSVRDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVETKEKQEEQIGLPGKGGKA
KGKKTQMAEVLPSPSGKRVIPRVTVEMKAEAEKKIKKKIKNENTEGSPPEDSIELEGLKQ
RLEKKQKREPGTKTKKQTTLPFKPIKKGKKRNPWSDSESDMSSDESNFDVPPREIEPRRA
ATKTKFTVDLDSDDDFSDFDEKTQDEDFVPSSDISPLKTKASPKHTTKELKPQKSATSVM
DLDADDAKDSVPFPAGSAADFSADTEIPNPVSKKKVAVKKTAAKSQSSTSSAGAKKRAAP
KGSKTDPGWNSDVPQKPDAPKTKIRRKRKPSTSDDSDSNFEKMISKAVTNKKSKGESEDF
HLDLDSAVAPRAKSGRAKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccattgcagcctgtaaatgaaaatatgcaaatcagcaaaacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcaaaagaaaacccaactg
gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttacgatgaagatattggcattaactatagggaagtcacctttgtccctggg
ttgtacaaaatctttgatgagatcctagtcaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatgggaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggggccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataacatggggaga
gctggtgagatggaactcaaaccctttaatggggaagattatacatgtattaccttccag
cctgacttgtccaagtttaaaatgcaaagcctagataaagatattgttgcactaatggtt
agaagagcatatgatattgctggatcctcgaaagatgtcaaagtctttctcaatggaaat
aagctgccagtaaaaggattccgtagctatgtagatatgtatttgaaggataaggtagat
gaaactggcaatccactgaaaattatccacgaacaagtaaactccaggtgggaagtatgc
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagtcaagagctttggatcgacatgccaattaagtgaaaaattcatcaaa
gctgcaactggctgtggtattgtggaaagcatactaaactgggtgaagtttaaggcccaa
gtccaattaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
ctcgatgatgccaatgatgcagggggtcgaaactccaatgagtgtacacttatcctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtagttgggagagacaaa
tatggggttttcccacttagaggaaaaatactcaatgttcgagaagcttctcataaacag
atcatggaaaatgccgaaattaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttacggaaagataatgattatgaca
gatcaggaccaagatggttcccatatcaaaggcctgctgattaattttatccatcacaac
tggccctctcttctacggcatcgttttctggaagaatttatcactcccattgtaaaggtg
tctaaaaacaaacaagaaatggcattctatagccttcctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtactacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatactttgcagatatgaaaagacatcgtattcaattcaaatat
tctggtcctgaagatgatgctgccatcagcctggcctttagcaagaaacagatcgatgat
cgaaaggaatggttaactcatttcatggaggatagaaggcaacggaagttacttggcctt
cctgaggattacttgtatggacaaactaccacatatctgacatacaatgacttcataaat
aaggaacttatcctgttctcaaattctgataacgagagatctatcccatctatggtggat
ggcttgaaaccaggtcaaagaaaggttttgtttacctgtttcaaacggaacgacaagcga
gaggtgaaagttgcccagttagctgggtcagtggctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtactaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttgactcggttgttatttccacca
aaagatgatcatacattgaagtttttatatgatgacaatcaacgtgttgaacctgaatgg
tacattcctattatacccatggtgctgataaatggtgctgaaggaatcggtactgggtgg
tcctgcaaaatccccaactttgatattcgtgaagttgtaaataatatcaggcgtttgatg
gatggggaagaacctttgccaatgcttccaagttacaagaccttcaggggtactattgaa
gagctggctccaaatcaatatgtgattagcggcgaagtggctattcttaattccacaacc
attgaaatctcagagcttcctatcagaacttggacccagacatacaaagaacaggttcta
gaacctatgttgaatggaactgagaagacaccacctctcataacagattatagggaatac
catacagacactactgtgaagtttgttgtgaaaatgactgaagagaaactggcagaggca
gagagagtgggactacacaaagtattcaaactccaaactagtctcacatgcaactctatg
gtactttttgaccatgtaggatgtttaaagaaatacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattaattaaagttctgattcagagg
ggatatgattcagatcccgtgaaggcttggaaagaagcccagctaaaggtaccagatgaa
gaagagaatgaagagagtgacaatgaaaatgaagctgaaaagagtgactctgtaagagac
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctcaccaaggagaag
aaggatgaactgtgcaagctgagaaatgaaaaagagcaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagagctggaggct
gttgaaacaaaggaaaaacaagaagaacaaataggacttcctgggaaaggggggaaagca
aagggaaaaaaaacacaaatggctgaagttttgccttctccgtccggtaaaagagtcatc
ccccgagtgaccgtagagatgaaagcagaggcagaaaagaaaattaaaaagaaaattaag
aatgaaaacactgaagggagccctccagaagacagtatcgaactagaaggtctgaaacaa
aggttggagaaaaaacagaaaagagaaccaggtaccaagacaaagaagcaaactacattg
ccatttaaaccaatcaaaaaaggaaagaagagaaacccctggtctgattcagaatcagat
atgagcagtgacgaaagtaactttgatgtccctccacgagagatagagccacggagggca
gcaacaaaaaccaaattcacagtggatttggattcagatgacgatttctcagattttgat
gaaaaaactcaagatgaggattttgttccatcatcagatattagtccacttaagaccaaa
gcttccccaaaacatactaccaaagaactgaagccgcagaaaagtgccacgtcagtaatg
gaccttgatgctgatgatgccaaggacagtgtaccatttcctgcaggttctgctgctgat
ttctcagctgacactgaaatcccaaaccctgtttctaaaaagaaggtggcagtgaagaag
acggcagcaaaaagtcagtcttccacctccagtgcaggtgccaaaaaaagggctgcacca
aaaggatccaaaacggatccaggctggaattctgatgtaccccagaagcctgatgccccc
aaaaccaaaattcgccgcaaaaggaagccatccacgtctgatgattccgactctaatttt
gagaaaatgatttctaaagccgtcacaaacaagaaatccaagggggagagtgaagacttc
catctggacttagactcagctgtggctcctcgggccaaatctggacgggcaaagaaacct
ataaagtacctcgaagaatcagacgaagatgatctgttctaa
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integrated database retrieval system
