| Entry |
|
|---|
| Symbol |
ABCC2
|
|---|
| Name |
(RefSeq) canalicular multispecific organic anion transporter 1
|
|---|
| KO |
| K05666 | ATP-binding cassette, subfamily C (CFTR/MRP), member 2 |
|
|---|
| Organism |
mlx Mirounga leonina (Southern elephant seal)
|
|---|
| Pathway |
| mlx04981 | Folate transport and metabolism |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:mlx00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
118024908 (ABCC2)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
118024908 (ABCC2)
04981 Folate transport and metabolism
118024908 (ABCC2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118024908 (ABCC2)
01523 Antifolate resistance
118024908 (ABCC2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mlx02000]
118024908 (ABCC2)
Transporters [BR:mlx02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
118024908 (ABCC2)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
Unknown
|
|---|
| AA seq |
1542 aa
MLEKFCNSTFWNSSFLDSPEADLPLCFEQTVLVWIPLGFLWFLAPWQLLHVYRSKIKRSP
ITKLYLAKQVLVGFLLILAAIELALVLTEDSGQATVPAIRYTNPSLYLGTWLLVLLIQHS
RRWCMQKDSWFLSLFWILSILCGIFQLQTLIRTLLKGSSSNLAYSCLFFICYALQILILI
LSAFSEKDASSTNPSFTASFLSSITFSWYDSIIMKGYKQPLTLEDVWDVDEEIKTKALVS
TFEKHMVGELQKARKALQGRQRRKAWRASGDGLRGLNKNQSQSQDIIVLEEVKKKSGTTE
DFPKSWLVKTLFKTFYIMLLKSFLLKLVHDLLMFLSPQLLKLLISFTNDRDAHVWTAYLY
SVLFFVVALIQSLCLQCYFQMCFRLGVSVRTTVMASIYRKALTLSNQARKQYTIGETVNL
MSVDAQKLMDVTSYFHLLWSDVLQITLSIYFLWAELGPSILAGVGVMVLLIPVNAILAAK
SRAIQVKNMKNKDKRLKIMNEILSGIKILKYFAWEPSFKNQVHELRKKELKNLLAFGQMQ
SVIVFLLYLTPVLVSVITFSVYALVDSNNVLDAEKAFTSITLFNILRFPLSMLPMVISSI
LQASVSRDRLEQYLGGDDLDPSAICRLDCNFDKAVQFSEASFTWDQDSEATIRDVNLDIM
PGQLVAVVGTVGSGKSSLMSAMLGEMENVHGHITIKGTIAYVPQQSWIQNGTIRDNILFG
SELDEKRYQQILEACALLQDLEVLPGGDLAEIGEKGINLSGGQKQRISLARAIYQNSDIY
VLDDPLSAVDAHVGKHIFNKILGPKGLLKGKTRLLVTHSIHFLPQVDEIVVLGNGTILEK
GSYSTLLAKKGSFAKILKTFTKQTGPVEEATVNEDTEEEDDCGLMPSVEEIPEDVASLTM
KRENSLHQILSRNSRSNSRHRKSLRNSLKTRNVNTLKEEEEPVKGQKLIKKEFIQTGKVK
FSIYLKYLQAVGWFSIFFIIFAYVINSVAYIGSNLWLSAWTNDSKTFNGTNYPASQRDLR
IGVYGALGLVQGAFVIIANLWNAYGSTHASNILHRQLLTNILQAPMSFFDTTPTGRIVNR
FSGDISTVDDTLPLSLRSWILCFLGIISTLVMICTATPIFIVVIIPLGLIYASVQIFYVA
TSRQLKRLDSVTRSPIYSHFSETMSGLSVIRAFEHQQRFLKHNEVGIDTNQKCVFSWITS
NRWLAVRLELIGNLIVFFSSLMMVIYRDTLSGDTVGFVLSNALNITQTLNWLVRMTSEIE
TNIVAVERINEYIKVENEAPWVTDKRPPPGWPSKGEIRFNNYQVRYRPELDLVLRGITCD
IRSMEKIGVVGRTGAGKSSLTNGLFRILEAAGGQIIIDGVDIASIGLHDLREKLTIIPQD
PILFSGSLRMNLDPFNNHSDEEIWKALELAHLKSFVSGLQLGLSHEVTEAGDNLSIGQRQ
LLCLARALLRKSKILVMDEATAAVDLETDHLIQTTIQKEFSHCTTITIAHRLHTIMDSDK
IMVLDNGKIVEYGSPQDLLRSSGPFYLMAKEAGIESVNSTSF |
|---|
| NT seq |
4629 nt +upstreamnt +downstreamnt
atgttggagaagttctgcaactctacattttggaattcttcattcttggatagtccagaa
gcggacctgccactttgttttgagcaaactgttctggtgtggattcccttgggtttcctt
tggttcctggccccttggcagcttcttcatgtgtatagatccaagatcaaaagatctcct
ataaccaaactctaccttgctaagcaggtgcttgttgggtttcttcttattctagcagcc
atagagctggcccttgtactcacagaagactctggacaagccacggtccctgccattaga
tacaccaatccaagcctttacctgggcacatggctcctggttttgttgatccaacatagc
aggcgatggtgcatgcagaaggattcttggttcctgtccctattctggattctctcaata
ctctgtggcattttccaattacagactctgatccggacactcttaaagggcagcagttct
aacctggcctattcctgcctgttcttcatctgctatgcactgcagatcctgatcctgatc
ctttcagcattttcagaaaaagatgcctcatcaactaatccatcattcacagcctcattt
ctgagtagcattacatttagttggtatgacagcatcattatgaaaggctacaagcaacct
ctgacacttgaagatgtctgggatgttgatgaagagattaaaaccaaggcactggtcagc
acgtttgaaaaacatatggtaggagagctgcagaaggccaggaaggcgctccagggacgg
cagcggaggaaggcctggagggcctctggagatgggctgcgtggcttgaacaagaatcag
agtcaaagccaagatatcattgtcctggaagaagttaaaaagaagtctgggaccacagaa
gactttcccaagtcctggttggtcaagactctcttcaagactttctacatcatgctcttg
aaatcattcctcctgaagctggtgcatgacctcctcatgtttctgagtcctcagctgctg
aaattgctgatctccttcacaaatgaccgagacgcacacgtgtggaccgcatatctctat
tcagtcctcttctttgttgtggccctcatccagtctctttgccttcagtgctactttcaa
atgtgcttcaggctgggtgtctccgtacggacaaccgtcatggcgtccatatataggaag
gcgctgaccctatccaaccaggccaggaagcagtataccattggagaaacagtgaacctg
atgtctgtggatgcccagaagctcatggatgtgactagctactttcatctgctgtggtca
gatgttctgcagattactttatctatctacttcctatgggcagagctgggaccctccatc
ttggcaggtgttggggtgatggtactcctaattccagttaatgcgatacttgctgccaag
agtagagctattcaggtaaaaaatatgaagaacaaagacaaacggttaaagatcatgaat
gaaattctcagtgggataaagatcctgaaatattttgcttgggaaccttcattcaaaaac
caagttcacgaacttcggaagaaagaactcaagaacctgctggcttttgggcagatgcag
tctgtaatcgtgtttctcttatacttaactccagtcctggtgtctgtgatcacattttca
gtttacgctctggtggatagcaataatgttttggatgcagaaaaggccttcacctccatc
accctcttcaatatcctgcgctttcccctgagcatgcttcccatggtaatctcctccatt
ctccaggccagcgtttccagagaccggctagaacagtacctgggaggggatgacttggac
ccctccgccatttgccgccttgactgcaattttgacaaagcagtgcaattctcagaggcc
tcctttacctgggaccaggactcagaagccaccatccgagatgtgaacctggacattatg
ccaggccagttggtggctgtggtaggcactgtgggctctgggaagtcctccttgatgtca
gccatgctgggagaaatggaaaatgtccatgggcacatcaccatcaagggcaccatagcc
tatgtcccgcagcaatcctggatccagaacggcaccataagggacaacatcctttttgga
tcagagctggatgaaaagagataccagcagattctggaagcctgtgcccttctccaagac
ttggaagtgctgcctggaggagacctggctgagattggagagaagggtataaatctcagt
gggggtcagaagcaacggattagcctggccagagctatctatcagaattcagacatctat
gttctggatgaccccctgtcagccgtggatgctcatgtgggaaaacatattttcaataag
atcttaggtcccaagggcctattgaaaggcaagactcgactcttggtgacgcatagcatt
cactttcttccccaagtggacgagatcgtggttctggggaatggcaccatcttggagaag
ggatcctacagcactctgctggccaagaaaggatcgtttgctaagattctgaagacattc
acaaaacagactggtcctgtggaagaggccacagtcaacgaggacactgaagaagaagat
gactgtgggctgatgcccagtgtggaggaaatccctgaggatgtggcctccttaaccatg
aaacgagagaacagtcttcatcaaatactcagtcgcaattctaggtccaatagcaggcat
cggaaatccctaagaaactctttgaaaactcggaatgtgaacaccctgaaggaggaggaa
gaaccagtgaaaggacagaaactaattaagaaggaattcatacaaactggaaaggtgaag
ttctccatctacctgaagtacctacaagcagtaggatggttttcgatattcttcatcatc
tttgcctatgtgatcaattctgtggcttatattggatccaacctctggctcagtgcttgg
accaatgactctaaaacctttaatggcactaactatccagcgtctcagagggacctgcga
attggcgtctatggagctctgggattagtacaaggtgcatttgtgatcatagcaaatctc
tggaatgcctatggttccactcacgcatcaaacatccttcataggcaactgctaaccaat
atccttcaagcacccatgagtttttttgacacaacacccacaggccggattgtgaacagg
ttttctggtgatatttccacagtggatgatacccttcccttatccttgcgcagctggata
ttgtgcttcctgggaataatcagcacccttgtcatgatctgcacggccactccaatcttc
attgtcgtcatcattcctcttggcctcatttatgcgtctgttcagatattttatgtggcc
acttcccgccagctgaaacgtctggactctgtcaccaggtccccaatctactctcacttc
agtgagactatgtcaggtttgtccgtcatccgtgcctttgagcaccagcagcgatttctg
aaacacaatgaggtggggattgacaccaaccagaaatgtgtcttctcctggattacctct
aacaggtggcttgcagttcgtctggagctgattgggaacctgattgtcttcttttcatcc
ctgatgatggttatttatagagataccctaagtggagacactgtgggctttgttctgtcc
aatgcacttaatatcacacagaccctgaactggctagtgaggatgacgtcagaaatagag
accaacattgtggctgttgaaagaataaatgagtacataaaagtggaaaacgaggcaccc
tgggtgactgataagagaccccccccaggttggcccagcaaaggggagatccggtttaac
aattaccaagtgcggtaccggccggagctggatcttgtattgagagggatcacttgtgac
atcaggagcatggagaagattggtgtggtcggcaggacaggagctgggaagtcatccttg
acgaatggcctcttcagaatcctagaggctgcaggtggccagatcatcattgatggagta
gatattgcttccattgggctccatgacctccgagagaaactgaccatcatcccccaggat
cccatcctgttctctggaagcctgaggatgaacctagacccttttaacaaccactcagat
gaggagatttggaaggccctggagctggctcacctcaaatcctttgtgtctgggctgcaa
cttgggttgtctcacgaagtgacagaggctggtgacaaccttagcatagggcagaggcag
ctgctgtgcttggcccgcgctctgcttcggaaatccaagattctggtcatggacgaggcc
acggccgccgtggatctagagactgatcacctcatccagacgaccatccagaaggagttc
tcccactgcaccaccatcaccatcgctcacaggctgcacaccatcatggacagtgacaag
ataatggtcctagacaatgggaagattgtagagtatggcagccctcaagacctgctgaga
agttcaggccccttttatttgatggccaaagaagctggcattgaaagtgtgaacagcaca
tcattctga |
|---|
