Mirounga leonina (Southern elephant seal): 118025163
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Entry
118025163 CDS
T07472
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx04020
Calcium signaling pathway
mlx04022
cGMP-PKG signaling pathway
mlx04024
cAMP signaling pathway
mlx04148
Efferocytosis
mlx04260
Cardiac muscle contraction
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04380
Osteoclast differentiation
mlx04919
Thyroid hormone signaling pathway
mlx04972
Pancreatic secretion
mlx05010
Alzheimer disease
mlx05017
Spinocerebellar ataxia
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05410
Hypertrophic cardiomyopathy
mlx05412
Arrhythmogenic right ventricular cardiomyopathy
mlx05414
Dilated cardiomyopathy
mlx05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
118025163 (ATP2A3)
04024 cAMP signaling pathway
118025163 (ATP2A3)
04022 cGMP-PKG signaling pathway
118025163 (ATP2A3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
118025163 (ATP2A3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118025163 (ATP2A3)
09153 Circulatory system
04260 Cardiac muscle contraction
118025163 (ATP2A3)
04261 Adrenergic signaling in cardiomyocytes
118025163 (ATP2A3)
09154 Digestive system
04972 Pancreatic secretion
118025163 (ATP2A3)
09158 Development and regeneration
04380 Osteoclast differentiation
118025163 (ATP2A3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
118025163 (ATP2A3)
05017 Spinocerebellar ataxia
118025163 (ATP2A3)
05022 Pathways of neurodegeneration - multiple diseases
118025163 (ATP2A3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
118025163 (ATP2A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
118025163 (ATP2A3)
05414 Dilated cardiomyopathy
118025163 (ATP2A3)
05415 Diabetic cardiomyopathy
118025163 (ATP2A3)
Enzymes [BR:
mlx01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
118025163 (ATP2A3)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF3106
TNP-like_RNaseH_N
Motif
Other DBs
NCBI-GeneID:
118025163
NCBI-ProteinID:
XP_034883379
LinkDB
All DBs
Position
Unknown
AA seq
999 aa
AA seq
DB search
MEAAHLLPAADVLNRFSVRVESGLRPEQVSGARERYGPNELPTEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLACFEEGEETATAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRVRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAILDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLRTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSRAISVICVAVWVINISHFADPAHGGSWLHGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGSCRLHEFTVSGTTYAPEGEVRRAEQPVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTNVQALSRVERASACNAVIKQLMR
KEFTLEFSRDRKSMSVYCTPTGPGLAAQGSKMFVKGAPESVIERCSSVRVGGHTVPLTAT
CREQILAKIRDWGSGSDMLRCLALATRDAPPRKEDMQLDDCSKFVQYEADLTFVGCVGML
DPPRPEVAACIARCHQAGIRVVMITGDNKGTAVAICRRLGIFRDTEDVVGKAYTGREFDD
LSPEEQRHACRTACCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPHEALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDPEGPHVTFYQLRNFLKCSKDNPLFADIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVVVLQISLPVILLDEALKYLSRNHMDEEKDQK
NT seq
3000 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgcacctgctcccggccgccgacgtgctgaaccgcttctcggtgagggtc
gagagcggcctgaggccggagcaggtgtctggcgcgcgggagcgctacggccccaacgag
ctcccgactgaggaagggaagtccctgtgggagctggtgctggagcagtttgaggacctc
ctggtgcgcatcctgctgttggctgccctggtctccttcgtcctggcctgctttgaggag
ggtgaagagacagcaacagccttcgtggagcccctggtcatcatgctgatcctcgtggcc
aatgctatcgtgggcgtatggcaggaacgcaatgctgagagcgccattgaggccttgaag
gagtacgagcctgagatgggcaaggtgatccgctcagaccgcaaaggtgtgcagagggtc
cgtgcccgggacatcgtccctggagacattgtggaggtggcagtgggggacaaagtaccc
gctgacctccgcctcatcgagatcaagtccaccacactgagagtggaccagtccatcctg
acaggtgaatctgtgtctgtgaccaagcacacagatgccatcctggatcccagagctgtg
aaccaggacaagaagaacatgctcttctctggcaccaatatcgcatcgggcaaggccctg
ggtgtggcggtggccacaggcctgcgcacggagctgggcaagatccggagccagatggct
gcggtggagccggagcggacgccgctgcagcgcaagctggatgagttcgggcggcagctg
tcccgagccatctctgtgatctgtgtggccgtgtgggtcatcaacatcagccactttgct
gacccggcccatggcggctcctggctccatggcgctgtctactacttcaagattgccgtg
gccctggctgtggctgccatccctgagggcctcccggccgttatcactacctgcctggct
ctgggcacacggcgcatggcacgcaagaatgctattgtgcggagcctgccctccgtggag
accctgggctgcacctcagtcatctgctccgacaagaccggcacactcaccaccaaccag
atgtccgtctgccggatgttcgtggtagccgaggccgaagcaggctcctgccgtctgcac
gagttcaccgtctcaggcaccacttatgccccggagggcgaagtgaggcgggcggagcag
cctgtgcgctgtgggcagttcgatgggttggtggagctggcgacgatctgtgccctctgc
aacgactcggcgctggactacaacgaggctaagggcgtgtatgagaaggtaggagaggcc
acggagacggctctgacttgcttggtggagaaaatgaatgtgtttgacaccaacgtgcag
gccctatcccgggtggagcgagccagtgcctgcaatgcggtcatcaagcagctgatgcgc
aaggagtttactctggagttctcccgagaccggaagtccatgtcagtgtactgcacgccc
actggccctggcctggcagcgcagggcagcaagatgttcgtgaagggggctcctgagagt
gtgatcgagcgctgcagctcagtccgagtggggggccacacagtacccctgactgccacc
tgcagggagcaaatcctggccaagattcgggattggggctcaggctcagacatgttgcgc
tgcctggcactggccactcgggatgcaccccccaggaaggaggacatgcagctggacgac
tgcagcaagtttgtgcagtacgaggcggacctgacttttgtgggctgcgtgggcatgctg
gaccctccaaggcctgaggtggctgcttgcatcgcacgctgccaccaggccggcatccgt
gtggtcatgatcacaggggacaacaaaggcacagctgtggccatctgccgccggcttggc
atcttcagggacacagaggacgtggtggggaaggcctacacaggccgcgagttcgatgac
ctcagccccgaggagcagcgccacgcctgccgcacggcttgctgttttgcccgtgtggaa
cctgcgcacaagtcccgaatcgtagagaacctacagtcctttaatgagatcaccgccatg
accggagacggggtgaatgatgccccggctctgaagaaagcagagattggcattgccatg
ggctctggcacagctgtggccaagtcagcagctgagatggtgctgtcagatgacaacttt
gcctcgatcgtggccgcagtggaggagggacgtgccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctcacggcaatt
ctgggcctcccggaagccctgatccctgtgcagctgctctgggtgaacctggtgacagat
gggctacctgccacagccctgggctttaacccaccagacctggacatcatggagaagctg
ccgaggaaccctcatgaggccctcatcagcggctggctcttttttcgatatctggctatt
ggagtgtacgtgggcctggccacggtggctgctgccacttggtggttcctttatgatccc
gagggacctcacgtcaccttctaccaactgaggaacttcctgaagtgctccaaggacaac
ccactctttgctgacattgactgcgaggtcttcgagtcacgctttcccacaaccatggcc
ttgtctgtgctggtgaccattgaaatgtgcaatgccctcaacagcgtgtcggagaaccag
tcgctgctgcggatgccgccctggctgaacccttggctgctggccgctgtggccatgtcc
atggcgctgcacttcctcatcctattggtaccacccctgccccttattttccaggtgacc
ccactgagcgggcgccagtgggtggtggtgctccagatatctctgcctgtcatcctgctt
gatgaagccctcaagtacctgtcccggaaccacatggatgaagagaaggaccagaagtga
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