Mycobacterium marinum E11: MMARE11_48300
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Entry
MMARE11_48300 CDS
T04774
Symbol
gcs2
Name
(GenBank) glutamate--cysteine ligase, Gcs2
KO
K06048
glutamate---cysteine ligase / carboxylate-amine ligase [EC:
6.3.2.2
6.3.-.-]
Organism
mmae
Mycobacterium marinum E11
Pathway
mmae00480
Glutathione metabolism
mmae01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
mmae00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MMARE11_48300 (gcs2)
Enzymes [BR:
mmae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
MMARE11_48300 (gcs2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CP_ATPgrasp_2
CP_ATPgrasp_1
GCS2
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
CDM78966
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All DBs
Position
5794294..5796903
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AA seq
869 aa
AA seq
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MRRDPPRTMGVEEEFHLVDLRSRRLTTRAPDLLAKLPEDYVAELQSCVVETNSGIVDSLD
ALRADLLRHRRLLVDAADEIGVGVVAAGAVPLSVPAELQITQTPRYLHMLADYQLLAREQ
LICATHVHVGIDDRDEAIAIANRLLPCLPTLLALSASSPFWADGSDTGYASMRTLVWRRW
PTTGLAAPVQSATEYDALVKALIASQVITDYGMIYFDLRPSSHAPTLELRVCDSCPSVDT
IVLVAGLYRAAVAREAEAIRAGTPAPAFPSTVGSAALWRAARSGLEGDLVDLTGPVPASR
PAGDVVNDLVSSLRPQLEDSGDWEMIGELTRQTLLSGTSSARQRRALRRRGRLTDVVDQL
IAETAGRVKPTTAAISHDGGLLAAYQPTGEAGKPADDMFASYDEAVDADGRARPNYKTAL
KTIEGLGVDVLRARDRDIEQERRAGNVTFRAAGHSRVQVNPLDLVPRIVTADEWAQLSQG
LAQRARALDAFLRDVYSEQAILADGVLSAQVLDRSPGFRSTGRLAGDGVRAHISGIDLVC
DRAGNWMVLEDNLRIPSGVAYAIVNRRLLGKYLPELPPPGGVADLDRVAHLLLETLRAAA
PPHAPDQPTVTLLSAGRDDPGWFEHGFLAEEMGVALVAPSDLSVRDRRVFRHGGSGGSPV
DVIYSRMYEDMLLSSTGHDGAPLRSGLLEALDAGNLTIVNALGNGVAEDKAVYAFVPAMI
EYYLGEKPALAQVPTWVCAEREQRDYVLGHLGELVVKPTDGLSGSGVLIGPEATDAAIEA
RRRELLIQPERFVAQQLVALSTHPTFDDDGLYPHHVDLRAFVHLRQAPRGPVTAKVLPAA
LTRVASRGSRIANSSSGAGSKDTWIFTDG
NT seq
2610 nt
NT seq
+upstream
nt +downstream
nt
atgcgccgcgacccgccgcgaacgatgggcgtcgaggaggagttccaccttgtcgacctg
aggtccaggcgcctgacgacacgcgccccggacctgctcgcgaagcttccggaggactac
gtcgccgaacttcaaagctgcgtcgtcgagaccaacagcggcatcgtcgacagcctggac
gcgctgcgcgccgacctgcttcggcaccggcggttgttggtggacgcggccgacgaaatc
ggcgtgggcgtggtggccgccggcgccgtgccactgtcggtacccgccgagcttcagatc
acccagactccccgctacctgcatatgctcgccgactaccagctactcgcccgcgaacag
ctgatctgcgccacccatgtgcacgtcggcatcgatgaccgcgacgaagcgatcgccatc
gccaaccgcctgctcccctgtctgccgacgctgctggccttgtcggccagctcgccgttc
tgggccgacgggtcggacaccggctatgccagcatgcgcacgctggtatggcgacgatgg
ccgacgaccggcctggccgccccggtgcagtcggcaaccgagtacgacgcgctggtcaag
gcattgatcgccagccaggtgatcaccgactacggcatgatctacttcgatctccggccg
tccagccacgcgcccacgctagaactgcgagtgtgcgacagctgcccgtcggtggacacc
atcgtgctggtcgccggactgtaccgggccgccgtcgcgcgggaggccgaagcgatccgc
gccggcacccccgcgccggcgtttccctcgacggtgggcagcgcggcgctctggcgtgct
gcccgctcggggctcgagggcgacctcgtcgacctcaccgggcccgtcccggcgagccga
ccggccggggacgtggtcaacgatctggtgtcctcgctgcgaccgcagctcgaagacagc
ggcgactgggagatgatcggcgaactgacccgccagaccctgctctccggtacgtcctcg
gctcggcagcggcgggcgctgcgccgccgcggccgcctcaccgacgtcgtagatcagctc
atcgccgagaccgctgggcgcgtcaagcccacgaccgcggcgatatcgcacgatggtggc
ctgctcgcggcatatcagcccaccggcgaggccggcaaacccgccgacgacatgttcgcc
agctacgacgaagccgtcgatgccgacgggcgggcacgcccgaactacaagacggcactg
aagacgatcgagggcctcggcgtcgatgtgttgcgcgcccgcgaccgcgacatcgagcag
gaacgccgtgccggcaacgtcacgttccgggccgccgggcacagccgtgtgcaggtgaac
ccgcttgatctggtgccgcgaatcgtgaccgccgacgagtgggcgcagctgtcccagggc
ctcgcacaacgagccagggcgctggacgccttcctgcgagacgtctactccgagcaggcg
atcctggcggacggcgtgctcagcgcgcaggttctcgaccgctcgcccggtttccgttcg
accggccgactggccggcgacggcgtgcgtgcgcacatcagcggcatcgacctggtgtgc
gaccgcgcgggtaactggatggtgctggaagacaacctgcgcatcccgtccggtgtggcg
tacgcgatcgtcaaccgccggctgcttggcaagtacctgcccgagctgccaccgccgggc
ggggtcgccgatctggaccgggtcgcgcacctgctgctggagacgctgcgggcggcggcc
ccaccgcacgctcccgatcagccgacggtcaccctgttgtcggccggccgcgacgacccg
ggctggttcgaacacggattcctcgccgaggagatgggcgttgcactggtcgcgccatcg
gacctgtcggtgcgcgatcgcagggtgttccgccacggcggttctggcggttctccggtc
gacgtcatctattcgcggatgtacgaggacatgctgctttcatcgaccggccacgatggc
gcgccgctgcggtccggactgctcgaggcgctggacgccggcaacctcaccatcgtcaac
gcgctgggtaacggcgtcgccgaggacaaggcggtctacgcgttcgtccccgccatgatc
gagtactacctcggggagaagccggcgctggcgcaggtgccgacgtgggtctgtgccgaa
cgcgagcagcgcgattacgtgctgggtcatctgggcgagctggtggtcaagccgaccgac
gggctcagcggcagcggcgtgctgatcggcccggaggccaccgacgccgcgatcgaggcg
cgccggcgcgagctgctcatccaaccggagcggttcgtcgcccagcagctggtggcactc
tcaacgcacccaaccttcgatgacgatgggctctacccgcaccacgtcgacctgcgcgcg
ttcgtccacctacgacaggcaccccgcggcccggtgacggcgaaagtcctgcccgccgcc
ctgacccgagtggccagccgagggtcgcggatagcgaactcgtcgtcgggcgccggcagc
aaggacacctggattttcaccgacggctag
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