Mycolicibacterium madagascariense: MMAD_21020
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Entry
MMAD_21020 CDS
T06841
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
mmag
Mycolicibacterium madagascariense
Pathway
mmag00290
Valine, leucine and isoleucine biosynthesis
mmag00660
C5-Branched dibasic acid metabolism
mmag01100
Metabolic pathways
mmag01110
Biosynthesis of secondary metabolites
mmag01210
2-Oxocarboxylic acid metabolism
mmag01230
Biosynthesis of amino acids
Module
mmag_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
mmag00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
MMAD_21020 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
MMAD_21020 (leuC)
Enzymes [BR:
mmag01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
MMAD_21020 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
MMAD_21020 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
BBZ27807
UniProt:
A0A7I7XF48
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Position
2200208..2201641
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AA seq
477 aa
AA seq
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MTSTARTLAEKVWADHVVVSGQGEGAAREPDLIYIDLHLVHEVTSPQAFDGLRLAGRPVR
RTDLTIATEDHNVPTIDIDKPIADPVSRTQVETLRRNCEEFGVRLYPVGDAEQGIVHIIG
PQLGLTQPGMTVVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDG
VLPAGTSPKDVILAVIAKIGTGGGQGYVIEYRGSAIEAMSMEGRMTICNMSIEAGARAGM
VAPDETTFDYLRGRPHAPTGADWDEAVEAWSQLRTDEGAEFDAEVYLDASTLSPFVTWGT
NPGQGVPLSEAVPDPELMFDDGERQSAEKALAYMDLQPGTAMRDIRIDTVFVGSCTNGRI
EDLRVVADVLRGRRIAEGMRMLVVPGSMKVRVQAESEGLGEIFTAAGAEWRQAGCSMCLG
MNPDQLAPGERCAATSNRNFEGRQGKGGRTHLVSPAVAAATAVRGTLSSPADLTESR
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgaccagcactgcacgcactctggcggagaaggtctgggccgaccacgtcgtggtcagc
ggccagggagagggcgccgcgcgcgagccggacctcatctacatcgatctgcacctcgtc
cacgaggtcaccagcccgcaggccttcgacggacttcggttggcggggcggcccgttcgt
cgcaccgacctgacgatcgccaccgaggaccacaacgtgccgacgatcgacatcgacaag
ccgatcgccgaccccgtctcgcgcacccaggtcgagacgctgcgccgcaactgcgaggag
ttcggcgtccggctgtatcccgtgggcgatgccgagcagggaatcgtccacatcatcggt
ccacaactgggtctcacccaaccgggcatgacggtggtctgcggggacagccacacctcg
acccacggcgcgttcggtgcgctggcgatggggatcggcacctccgaggtcgaacacgtg
ctcgccacccagacactgccgctgcggccgttcaagaccatggccgtcaacgtcgacggc
gtgctgccggccggtaccagcccgaaggacgtcatcctcgccgtgatcgcgaagatcggc
accggcggcggacagggttacgtcatcgaatatcgcggcagcgccatcgaagcgatgtcg
atggagggccggatgacgatctgcaacatgagcatcgaggcaggcgcccgggccggcatg
gtcgctccggacgagacgacgttcgactatctgcgcggccgcccgcacgcccccacgggc
gccgattgggacgaggccgtcgaggcgtggagtcagttgcgcaccgacgagggagccgaa
ttcgacgccgaggtctacctcgacgcctcgacgctgagcccgttcgtcacgtggggtacc
aaccccggacagggtgtgccactgagcgaagccgtgcccgacccagaactgatgttcgac
gacggcgagcgtcagtccgccgagaaggccttggcgtacatggatcttcagccggggacg
gccatgcgcgacatccggatcgacacggtgttcgtggggtcgtgcaccaacggccgcatc
gaggatctgcgggtcgtcgcggacgttctgcgcggcaggaggatcgccgagggcatgcgg
atgctggtcgtgcccgggtcgatgaaggtcagggtgcaggccgaaagcgagggcctgggc
gagatcttcaccgccgcgggcgccgagtggcgccaagcgggatgctcgatgtgccttggc
atgaaccccgaccagctggcgccgggggagcgctgcgcggcgacgtcgaaccgcaacttc
gaagggcgccagggcaaggggggccgcacccacctggtgtcacccgcggtggccgcggcc
accgcggtgcgcggcaccctgtcctcgcccgccgatctgaccgagagtcgctag
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