Methylocaldum marinum: sS8_4640
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Entry
sS8_4640 CDS
T05638
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mmai
Methylocaldum marinum
Pathway
mmai00300
Lysine biosynthesis
mmai00550
Peptidoglycan biosynthesis
mmai01100
Metabolic pathways
mmai01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mmai00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
sS8_4640
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
sS8_4640
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
sS8_4640
Enzymes [BR:
mmai01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
sS8_4640
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
HEM4
Motif
Other DBs
NCBI-ProteinID:
BBA36570
UniProt:
A0A250KY56
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All DBs
Position
5025296..5026669
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AA seq
457 aa
AA seq
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MKVRLSDFCGIVGGELRGDDVAFEDLGIDTRSLKPGDLYLAIRGTRFDGNDFVAQAKSAG
ASAAVVERFADCDLPQVRVDDGRMALGCFAASWRDRWTGRLVGITGSNGKTTVKEMTAAI
LGVAAPVLKTQGNLNNDIGVPLMLLRLTDEYRFAAIEMGANHPGEIAYVGGLAKPDVAVI
SNAGAAHLEGFGSLEGVASAKGELIASLSAAGTAVLNADDRFFGRWREMARGRPVVSFGF
CADAAVRADADSIRMGLNEGKFLTSFDLLYRGERHPLALSLAGDHNVVNALAAAAAACAL
GFDIGRIRTGLSRVAPVPGRVEPVNGIRGSLLINDTYNANPTSFRAALHVLRQLSGDRWV
ALGAFGELGEASAELHAEIGGQARAMGVTRLFAVGPNADRAAEAFGDGAVYCREQDELIE
LIRQQINENVVLLIKGSRTQRMERVVEALRQRSDLCC
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtgcgactttccgatttctgcgggatcgtcggcggtgagctgcggggcgatgac
gtcgcgtttgaagacctaggcatcgacactcgctctttgaaacccggcgatctttatctg
gcaatccgcggaactcgcttcgacggcaacgatttcgtcgctcaggcaaagtcggcaggc
gcctccgcggcggtggtcgaacgcttcgccgactgcgatttgccgcaggtacgggtcgat
gacggacgcatggcactcgggtgttttgccgcgtcttggcgcgatcgctggaccgggcgg
ctcgtcggtatcaccggcagcaacggcaagaccactgtaaaggaaatgactgcggccatt
ctcggcgttgccgcgccggtgctaaaaacacagggcaatctcaataacgatatcggcgtt
cctttgatgttgctgcggttgacggacgaataccgattcgcggcgattgaaatgggcgct
aaccaccccggtgagatcgcgtatgtcggcggattggcgaaacccgatgtcgccgtgatt
tccaatgccggggcagcgcatttggaaggtttcggctcactcgagggggtggcgtccgca
aaaggggaactgattgcttcgctgagtgcggccggtacggcggtactcaatgccgacgat
cgttttttcggtcgctggcgcgaaatggcccgtggacgccccgtggttagtttcggattc
tgcgccgatgccgccgtgcgtgccgacgccgattcgataaggatggggctgaacgagggt
aagttcctcacctccttcgatcttttgtatcggggggagcgccatcctttggccctttcc
ctggccggcgatcataacgtggtcaacgccttggccgcggctgccgcggcctgcgctctg
ggtttcgatatcggccggatacgcacggggctgtcccgcgtggccccggtgccgggacgc
gtggagcctgtgaacgggattcggggatccttgctgatcaacgatacctataacgccaac
cccacttcttttcgggccgctttgcatgtgctacggcagctgtcgggtgatcgctgggtc
gccttgggcgcgttcggcgagctcggcgaggcgagcgccgaactgcatgccgagattggc
ggccaggcgagggcgatgggcgtgacgcggctgtttgccgtgggcccgaacgcggatcgg
gcggcggaagctttcggcgacggcgctgtgtactgccgggagcaggatgaattgattgaa
ctcatacgacagcagattaacgagaacgttgtgttattgattaaaggttcacgcacccag
cgtatggagcgggtggttgaggcattacggcagcggagcgatttatgctgctga
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