Mycobacterium mantenii: MMAN_03950
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Entry
MMAN_03950 CDS
T07431
Symbol
hemE
Name
(GenBank) uroporphyrinogen decarboxylase
KO
K01599
uroporphyrinogen decarboxylase [EC:
4.1.1.37
]
Organism
mman
Mycobacterium mantenii
Pathway
mman00860
Porphyrin metabolism
mman01100
Metabolic pathways
mman01110
Biosynthesis of secondary metabolites
mman01240
Biosynthesis of cofactors
Module
mman_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mman00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MMAN_03950 (hemE)
Enzymes [BR:
mman01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.37 uroporphyrinogen decarboxylase
MMAN_03950 (hemE)
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Gene cluster
GFIT
Motif
Pfam:
URO-D
Motif
Other DBs
NCBI-ProteinID:
BBY36261
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Position
384993..386042
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AA seq
349 aa
AA seq
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MSTRRDLPESPYLAAVSGRKPSRVPVWFMRQAGRSLPEYRALRAQTDMLSACFDSELVSE
ITLQPVRRHDVDAAILFSDIVVPLLGADIDLDIVAGVGPVIASPVRTAADVAAIKPLERQ
RVQPVSDAVSLLVSALGDVPLIGFAGAPFTLASYLIEGGPSRHHARTKAMMLAEPDTWHA
LMEKLTDITVGFLRVQLEAGVDAVQVFDSWAGALSLANYRSYVQPHSARVFAALADYGVP
MTHFGVGTAELLGAMSSVGANVVGVDWRTSLADAAARVQPGTALQGNLDPVVVLAGWPVV
ERAARAVVDDGRRAIDAGAAGHVFNLGHGVLPETDPGVLTDLVSLVHSL
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
atgagtactcgccgcgatcttcccgagtcgccgtatctggcggccgtgagcggccgcaaa
cccagccgggtgccggtgtggttcatgcggcaggccggtcgctcgctgcccgaataccgg
gcgctgcgagcccagaccgacatgctgtcggcctgcttcgactccgagttggtcagcgag
atcaccctgcagccggtgcgccgccacgacgtcgacgccgcgatcctgttctccgacatc
gtggtgccgttgctcggcgccgacatcgacctggacatcgtcgcgggcgtcggcccggtc
atcgcgtcgccggtgcgcaccgccgccgacgtggcggcgatcaaaccccttgagcggcaa
cgggttcaaccggtatccgacgcggtgtcgctgctggtgtccgcgctcggcgatgttccg
ctgatcggctttgcgggcgccccgttcaccttggcgtcctatctgatcgagggcggcccc
agccgccaccacgcgcgcaccaaggcgatgatgctggccgagccggacacctggcacgcg
ctgatggagaagctgaccgacatcaccgtgggcttcctgcgggtgcagctggaggccggg
gtggacgccgttcaggtgttcgactcgtgggccggggcgctgtccctggcgaattaccgc
agctacgtgcagccgcacagcgcccgggttttcgccgcgcttgccgactacggcgtgccg
atgacccacttcggggtcggcaccgccgaactgctgggcgcgatgtcgtcggtcggcgcg
aacgtggtgggcgtcgattggcgaacctccctggccgatgcggccgcccgcgtgcaaccc
ggcacggcattgcagggcaacctcgatccggtggtggtgctggcgggctggccggtggtg
gaacgcgcggcgcgcgccgtcgtggacgacggccggcgcgcgatcgacgccggggccgcc
ggtcacgtcttcaacctcggccacggcgtgctgcccgagaccgaccccggtgtgctgacc
gacctggtgtcgctggtccactccctatga
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