Mycobacterium mantenii: MMAN_21740
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Entry
MMAN_21740 CDS
T07431
Symbol
bkdA_1
Name
(GenBank) 2-oxoisovalerate dehydrogenase E1
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
mman
Mycobacterium mantenii
Pathway
mman00280
Valine, leucine and isoleucine degradation
mman00640
Propanoate metabolism
mman00785
Lipoic acid metabolism
mman01100
Metabolic pathways
mman01110
Biosynthesis of secondary metabolites
mman01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mman00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MMAN_21740 (bkdA_1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MMAN_21740 (bkdA_1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMAN_21740 (bkdA_1)
Enzymes [BR:
mman01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MMAN_21740 (bkdA_1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
DUF2478
DraK_HK_N
PFOR_II
PRAS_NT
PDE8A_N
Motif
Other DBs
NCBI-ProteinID:
BBY38040
UniProt:
A0ABM7JR50
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All DBs
Position
2377739..2379718
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AA seq
659 aa
AA seq
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MSGSFSTDELLEMYYRMLLIRNFEQRTSRLYAEGQVPGFVHLSIGQEASAVGTCWPLRST
DGIVSNHRGHGHCLAKGADPTSMFGELMGRAIGTGGGMGGSMHIADFDRGIYGANGIVGA
GLPIAVGVAEGFRQQNRDDVVVAFFGDGAIAQGAFHEAVNLAAVRGLPVLFVCENNQYSE
FSSFDEQHPVPVTARASAYGIDCASVDGNDVVAVAAAAMSFVSRMRAGEGPFLLETITYR
WHGHYEGDPMPYRTDAELAQWKERDPIAALASALRDRVDRPAMSSVEARAERVTAEAETA
ASGAAPPDPSMLSDAVEVGRVAAAPARLEPVTADGDRGFKVMHAVHAALEYSLQTDPTVF
VAGVDVGGGNVFGLTRGLRDSFGQRVFDTPISESAVVGLAVGAAMTGCKPIVEIMYFDFI
GVAFDQIMNQAAKIHFMTGGRAPAALVIRTQFGSGRSSAAQHSQSLEALLSHIPGLTVVM
PSTAEDTYGLLRAAIMDPNPVIFVEHRLQYGLKGIRPDPDYVVPLGQAAIRRQGCDVTLV
SWSRMAQTALAAANQIASEGIDVEVIDLRTVAPFDLECVLRSVRKTNRLVIAHEAHGKGG
LGAEIAAQIADIGVWHLDAPIKRVTPPFTPAPYSPDLEQIWLPGPKQIIDAIREVVADK
NT seq
1980 nt
NT seq
+upstream
nt +downstream
nt
gtgtcaggctctttctcaacggacgaactgctagagatgtattaccggatgttgctcatc
cggaatttcgagcaacgcacctcacggctctacgccgagggccaggtgccgggctttgtg
catctgtcgatcggacaagaggcatcggccgttgggacttgctggccgttgcgctcaacg
gatggaatcgtttcgaatcatcggggccatggacactgcctcgccaagggcgcggatccc
acatcgatgttcggtgagctgatgggcagggcgatcggtaccggcggcggcatgggcggg
tcgatgcacatcgccgacttcgaccgtgggatttatggtgccaacggaatcgtcggcgca
gggttgccgatcgcggtgggcgttgccgagggtttccgccagcagaatcgcgatgacgtc
gtggttgcgttcttcggcgacggcgccattgcccaaggcgccttccacgaagccgtgaat
ctcgctgccgtgcgcggccttcccgttcttttcgtgtgtgagaacaaccagtattcggag
ttctcgtctttcgacgagcagcaccccgtgccggtcaccgcccgtgcttcggcctacggg
atcgattgtgcgtcggtcgacggcaacgacgttgtcgcggtcgcggccgccgcaatgtca
ttcgtgtcgcgtatgcgtgccggcgaggggccgttcctcctcgaaacgatcacttaccgt
tggcacggccactatgaaggcgacccaatgccgtatcggaccgatgcggagttggcgcaa
tggaaagagcgggatccgatcgctgcgctggcctcggcgttgcgcgaccgggttgaccgc
cctgctatgtcctcggtcgaggcgcgagctgaacgggtgaccgccgaagccgagactgcg
gccagcggcgccgcaccaccggacccgtcgatgttgtccgatgcggtcgaggttgggcga
gtggccgctgctcctgcgcgactggagccggtcaccgcagatggggatcgcgggttcaag
gtcatgcacgccgtgcatgcggcacttgagtattcgctgcaaacagaccccacggtcttc
gtagccggcgtcgatgtgggcggtggcaatgtcttcggtctgactcgcggattgcgcgac
agcttcggacaacgagtcttcgacaccccgatctcagaaagtgccgtcgtgggcctggcc
gtaggcgcggcgatgacgggctgtaagccgatagtcgaaatcatgtacttcgacttcatc
ggcgtagcgttcgatcaaatcatgaatcaggccgccaagattcacttcatgaccggtggc
cgagcgcccgccgcgctggtgatcaggacgcagttcggctcggggcggtcgtctgcggca
cagcactcgcagagcctcgaagctctgctctcccacatacccggcctcaccgtcgtgatg
ccgtccaccgccgaagacacctacggcctgctacgcgcagcgataatggatcccaatccc
gtcattttcgtcgagcaccgactccaatacgggctcaagggcattcggccggaccccgat
tatgtcgttcctctgggccaagcggcgatccggcgccagggttgcgatgtcacgctggtg
agttggtcacggatggcgcaaaccgcgctggccgcggcgaatcagattgcttccgaaggc
atcgatgtcgaggtcatcgacctgcgcaccgtggcaccattcgacctggagtgcgttctg
cgatctgtgcgaaagacgaaccggctcgtgattgctcacgaggcgcacggcaagggcggg
ctcggcgccgagatcgcggcgcagatcgccgatataggtgtatggcatctcgacgccccg
atcaaacgtgtgacaccgccattcacccctgcgccgtattcgcctgacctagaacagatc
tggctcccaggcccaaagcagatcatcgatgcgatacgcgaagtggttgccgacaaatag
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