Mycobacterium mantenii: MMAN_33560
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Entry
MMAN_33560 CDS
T07431
Symbol
hemD
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mman
Mycobacterium mantenii
Pathway
mman00860
Porphyrin metabolism
mman01100
Metabolic pathways
mman01110
Biosynthesis of secondary metabolites
mman01120
Microbial metabolism in diverse environments
mman01240
Biosynthesis of cofactors
Module
mman_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mman_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mman00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
MMAN_33560 (hemD)
Enzymes [BR:
mman01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
MMAN_33560 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
MMAN_33560 (hemD)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
BBY39222
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Position
complement(3672333..3673994)
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AA seq
553 aa
AA seq
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MTTRGRKPTPGRITYVGSGPGDPGLLTTRAATVLANAALVFTDPDVPEPVLALIGKDLPP
VSGPAPAEPAAANGDGVSDQGKAQPAVMSGGPDIRPALGDPAEVAKTLTTEARTGADVVR
LVAGDPLTVDAVITEVNAIARSHLHIEIVPGLAPSDAVPTYAGLPLGSSHTVADVRDPHV
DWEALAAAPGPLILQATSSHLADAARTLIEHGLAENTPCVVTAHGTTCQQRSIETTLHGL
TDSAVLGGTDPAGPLTGPLVVTIGKTVASRAKLNWWESRALYGWTVLVPRTKDQAGEMSE
RLTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEFG
LDARAFSGVKIACVGESTADRVRAFGISPELVPAGEQSSLGLLDDFPPYDSIFDPVNRVL
LPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPAETREMIKTGGFDAVCFTSSSTV
RNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRAE
GALPPPRKKSRRR
NT seq
1662 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgcgaggccgtaagccgacacccggccgcatcacgtacgtgggctccggcccg
ggtgacccgggattgctgacgacccgggccgcgacggtgctggcgaacgccgctttggtg
ttcaccgaccctgacgtgcccgagccggtgctggccctgatcggcaaagacctgccaccg
gtttccggcccggccccggccgagccggccgccgctaacggtgacggtgtttccgaccag
ggcaaggcgcagccggcggtgatgtccggcggtcccgatatccgcccggcgctgggcgac
cccgccgaggtggccaagacgctgaccaccgaagcgcggacgggcgccgacgtggtgcgg
ctggtggccggcgacccgctgacggtcgacgcggtcatcaccgaggtgaacgccatcgcg
cgcagccacctgcacatcgagatcgtccccggactggcccccagcgatgccgtcccgacg
tacgcggggttgccgctgggctcatcgcacaccgtcgccgatgtgcgcgacccgcatgtg
gattgggaggcgctggccgcggcgcccggtccgctgattctgcaggccacgtcgtcgcac
ctggccgacgcggcgcgcaccttgatcgagcacgggctcgccgagaacaccccgtgcgtg
gtgaccgcgcacggcaccacctgccagcagcggtcgatcgagaccacgctgcacggcttg
accgactcggcggtgctgggcggtaccgaccccgccggcccgctgaccggtccgctcgtg
gtgaccatcggcaagacggtggccagccgggcgaaactgaactggtgggagagccgcgcg
ctgtacggctggaccgtgctggtgccccgcaccaaggaccaggccggcgagatgagcgag
cgcctgacgtcctacggcgcactgccgatcgaggtgccgaccattgccgtcgagccgccg
cgcagcccggcccagatggagcgggccgtcaagggattggtcgacggccgcttccagtgg
gtggtattcacctccaccaacgcggtgcgcgcggtctgggagaagttcggcgaattcggc
ctggatgcgcgcgcattctccggagtcaaaatcgcgtgtgtcggtgagtcgaccgccgac
cgggtccgggcgttcgggatcagcccggaactggtgccggccggcgagcagtcttcgttg
ggtctgcttgacgatttcccgccctacgacagcattttcgacccggtcaaccgggtgctg
ctgccgcgggccgacatagccaccgagacgctggccgagggtctgcgcgaacgtggttgg
gagatcgaggatgtgaccgcctaccggacggtgcgggcggctccgccgccggcggaaacg
cgggaaatgatcaagaccggcggcttcgacgcggtgtgcttcacgtccagctccacggtg
cggaacctggtcggcatcgccggtaagccgcacgcgcggacgatcatcgcctgcatcggt
ccgaagaccgccgagaccgcggcggaattcggcctgcgggtggacgtgcagcccgagacc
gccgctgtcggtccgctggtcgacgctctggccgaacacgccgcgcggttgcgcgccgag
ggtgcgctgccaccgccgcgcaaaaagagccgcaggcgctag
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