Martes martes (European pine marten): 308342287
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Entry
308342287 CDS
T12008
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform 1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
mmaq Martes martes (European pine marten)
Pathway
mmaq01521
EGFR tyrosine kinase inhibitor resistance
mmaq04151
PI3K-Akt signaling pathway
mmaq04217
Necroptosis
mmaq04380
Osteoclast differentiation
mmaq04550
Signaling pathways regulating pluripotency of stem cells
mmaq04620
Toll-like receptor signaling pathway
mmaq04621
NOD-like receptor signaling pathway
mmaq04630
JAK-STAT signaling pathway
mmaq04658
Th1 and Th2 cell differentiation
mmaq04659
Th17 cell differentiation
mmaq05140
Leishmaniasis
mmaq05145
Toxoplasmosis
mmaq05152
Tuberculosis
mmaq05160
Hepatitis C
mmaq05161
Hepatitis B
mmaq05162
Measles
mmaq05163
Human cytomegalovirus infection
mmaq05164
Influenza A
mmaq05165
Human papillomavirus infection
mmaq05166
Human T-cell leukemia virus 1 infection
mmaq05167
Kaposi sarcoma-associated herpesvirus infection
mmaq05168
Herpes simplex virus 1 infection
mmaq05169
Epstein-Barr virus infection
mmaq05171
Coronavirus disease
mmaq05200
Pathways in cancer
mmaq05203
Viral carcinogenesis
mmaq05212
Pancreatic cancer
mmaq05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmaq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
308342287 (JAK1)
04151 PI3K-Akt signaling pathway
308342287 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
308342287 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
308342287 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
308342287 (JAK1)
04621 NOD-like receptor signaling pathway
308342287 (JAK1)
04658 Th1 and Th2 cell differentiation
308342287 (JAK1)
04659 Th17 cell differentiation
308342287 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
308342287 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
308342287 (JAK1)
05203 Viral carcinogenesis
308342287 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
308342287 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
308342287 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
308342287 (JAK1)
05161 Hepatitis B
308342287 (JAK1)
05160 Hepatitis C
308342287 (JAK1)
05171 Coronavirus disease
308342287 (JAK1)
05164 Influenza A
308342287 (JAK1)
05162 Measles
308342287 (JAK1)
05168 Herpes simplex virus 1 infection
308342287 (JAK1)
05163 Human cytomegalovirus infection
308342287 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
308342287 (JAK1)
05169 Epstein-Barr virus infection
308342287 (JAK1)
05165 Human papillomavirus infection
308342287 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
308342287 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
308342287 (JAK1)
05140 Leishmaniasis
308342287 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
308342287 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmaq01001
]
308342287 (JAK1)
Enzymes [BR:
mmaq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
308342287 (JAK1)
Protein kinases [BR:
mmaq01001
]
Non-receptor tyrosine kinases
JAK family [OT]
308342287 (JAK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
SH2_1
FERM_F1
ABC1
SH2
RIO1
FERM_C_FAK1
DUF4079
Motif
Other DBs
NCBI-GeneID:
308342287
NCBI-ProteinID:
XP_080658746
LinkDB
All DBs
Position
4:138784615..139006704
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEI
CIRAAQECCISPLCHNLFALYDENSKLWYAPNRAITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMMKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSMLLISSENEMN
WFHPNDSGSVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKHKKDEEKNKIR
EEWNNFSYFPEITHIVIKESVVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIVQGEHLGRGTRTHIYSGT
LVDYKDDEGTSEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKFKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLSRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSERKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
YSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPLHCPDEVYQLMRKCWEFQPSNRTT
FQNLIEGFEALLK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaggaggactgcaatgccatggctttctgtgctaaaatgagg
agctccaagaagacagaggtgaatctggaggcccccgagccaggagtggaagtgctcttc
tatctttctgatagggagcccctccggctgggcagcggagagtacaccgcggaggagatc
tgcattagggcggcgcaggaatgctgtatctctcccctgtgtcacaacctctttgccctg
tatgacgagaacagcaagctctggtatgccccgaatcgtgccatcactgttgacgacaag
acatccctccggctccactaccggatgaggttctatttcaccaactggcatgggaccaat
gataatgagcagtctgtatggcgacattctccaaagaagcagaaaaatggctatgagaaa
aaaaaagtcccagatgcaacccctctccttgatgccagttctttggaatatctgtttgct
cagggacagtatgatttggtcaaatgcctggctcccattcgagaccccaagaccgagcaa
gatggacacgatattgagaatgagtgtctgggaatggctgtcctggccatctcccactat
gccatgatgaagaagatgcagttgccagaacttcccaaggacatcagctataagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgcggata
aataatgttttcaaggatttcctgaaggaatttaacaacaagactatttgtgacagcagt
gtatctactcatgacctaaaggtgaagtacctggccaccttggaaacactgacaaaacat
tatggcgcagaaatatttgagacttccatgttactgatttcatcagaaaatgagatgaat
tggtttcatccgaacgacagtggaagcgttctctactatgaagtgatggtaactggaaat
cttggaatccagtggagacagaaaccaaatgttgttcctgttgaaaaggaaaaaaacaaa
ctgaaacggaaaaaactggaaaataaacacaagaaggatgaggagaaaaataaaatccgg
gaagagtggaacaatttttcttacttccctgaaatcactcacattgtaataaaggagtct
gtggtcagcatcaataagcaggacaacaaaaaaatggaactgaagctctcgtcccacgaa
gaggccttgtcctttgtgtccctggtagatggctacttccggctcacagcagatgcccat
cattacctctgcaccgatgtggctcccccattgatcgtccacaacatacagaatggttgt
cacggtccaatctgcacggaatatgccatcaataagttgcggcaagaaggaagcgaggag
gggatgtatgtgctgaggtggagctgtaccgactttgacaatatccttatgacggtcacc
tgctttgagaaatctgaggtgctgggtggccagaagcagttcaagaactttcagatcgaa
gtgcagaagggccgctatagcctgcatggctcggaccgcagcttccccagcctgggggac
ctgatgagccacctcaagaagcagatcctgcgcacggataacatcagcttcgtgctgaag
cgctgctgccagcccaagccccgagagatctccaatctgctggtggctacgaagaaagcc
caggagtggcagcctgtctaccccatgagccagctgagttttgaccggatcctcaagaaa
gatattgtgcaaggtgagcatctcgggagaggcacacggacacacatctactccggcacc
ctggtggattacaaggatgacgaaggaacttccgaagagaagagaataaaagtgatcctc
aaagtcttagaccccagccacagggacatttctctggccttctttgaagcagccagcatg
atgaggcaggtctcccacaaacacatcgtgtacctctatggtgtctgtgtccgagatgtg
gagaatatcatggtggaggagtttgtggaaggggggcccctggatctcttcatgcaccgg
aaaagcgatgtcctcaccacaccatggaagttcaaagttgccaaacagctagccagcgcc
ctgagttacttggaggataaagacctggtccacggaaatgtgtgcacgaaaaaccttctc
ctggcccgtgagggcattgacagcgagtgtggcccgttcatcaagctcagtgaccctggc
atccccatcaccgtgctgtccaggcaagagtgcatagaacgaatcccgtggattgctccc
gagtgtgttgaagactccaagaacctgagtgtggctgctgacaaatggagctttggaacc
acactctgggaaatctgctacaatggcgagatccctctgaaagataagaccctgatcgag
aaagagagattctatgaaagccggtgccggccagtgacgccatcttgtaaggagctggct
gacctcatgacacgctgcatgaactatgaccccaaccagagacccttcttccgagccatc
atgagagacatcaacaaactagaagagcagaatccagacattgtttctgaaagaaagccg
gcaactgaagtagatcccacacattttgaaaagcggttcttgaagaggatccgtgacttg
ggagagggccactttgggaaggttgagctctgcaggtacgaccctgagggggacaatact
ggggagcaggtggcagtgaaatccctgaagcccgagagtggaggcaaccacatagctgat
ctgaagaaggaaattgaaatcctaaggaacctctatcacgagaacattgtgaagtacaaa
ggcatctgtacggaagatggaggaaatggtattaagctcatcatggaatttctgccttca
ggaagccttaaggaatatcttccaaagaataagaacaaaattaacctcaaacagcaatta
aaatacgccgttcagatttgtaaggggatggactatttgggttctcggcagtacgttcac
cgggacttggcagcaagaaacgtcctcgttgagagtgagcaccaagtgaaaattggagac
tttggtttgaccaaagcaatcgaaactgacaaagagtactacaccgtcaaggatgatcgg
gacagccccgtgttttggtatgctcccgaatgtttaattcagtgtaaattttacatcgcc
tctgatgtctggtcgtttggagtgactctgcatgagttgcttacttactgtgattcagat
tacagccccatggcgttgttcctgaaaatgataggcccaactcatggccagatgacagtc
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacttcactgtcca
gatgaggtttatcaacttatgagaaaatgctgggagttccaaccatccaatcggacaact
tttcagaaccttatcgaaggatttgaagcacttttaaaataa
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integrated database retrieval system
