Martes martes (European pine marten): 308347872
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Entry
308347872 CDS
T12008
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
mmaq Martes martes (European pine marten)
Pathway
mmaq05012
Parkinson disease
mmaq05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmaq00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
308347872 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
308347872 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmaq01001
]
308347872 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmaq04131
]
308347872 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmaq04147
]
308347872 (LRRK2)
Enzymes [BR:
mmaq01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
308347872 (LRRK2)
Protein kinases [BR:
mmaq01001
]
Serine/threonine kinases: TKL group
LRRK family
308347872 (LRRK2)
Membrane trafficking [BR:
mmaq04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
308347872 (LRRK2)
Exosome [BR:
mmaq04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
308347872 (LRRK2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR-B
Ras
COR-A
LRR_14
ARMC6
Beta-prop_RSE1_2nd
LRR_9
LRR_NXF1-5
Arf
LRR_13
Beta-prop_EML_2
Beta-prop_IFT122_1st
AAA_22
T2SSE
nSTAND3
G-alpha
PduV-EutP
Kdo
ABC_tran
GTP_EFTU
SRPRB
MMR_HSR1
TniB
Ank_2
AAA_7
AAA_16
TsaE
MobB
Septin
NB-ARC
AAA_29
NACHT
HHO5_N
TrwB_AAD_bind
nSTAND_NTPase5
cobW
AAA_SelU
Motif
Other DBs
NCBI-GeneID:
308347872
NCBI-ProteinID:
XP_080667765
LinkDB
All DBs
Position
8:76538931..>76670366
Genome browser
AA seq
2527 aa
AA seq
DB search
MASGSCQGCEEEDEETLKKLIVRLNNVQEGKQIETLVQILEDMLVFTYADHASKLFQGKK
VHVPVLIVLDLYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGHDWEVLGVHQLIL
KMLTVHNANVNLLTVGLKALDLLLTSGKITLLILDEESDIFLLIFDAMRTFSANDEVQKL
GCKALHVLFERVSEEQLTEFVENKDYMILLNALKNFKDEEEIVLHVLHCLHSLAIPCNNV
EVLMSGNVRCYNIVVEAMKTFPVNEKVQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAV
RRYSENATLQIAALSCLALLTETIFLNQDLEEKNENQENDDEEEDKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQSSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLELMQRHIHSPEVAESGCKMLNHLFEGSNTTLDTM
AAVAPKIITVMKSHETSLSVQLEALRAVLHFIVPGMSEESREDTEYQHKLNMVKKQCFKN
DIHKLVLAALNKFIGNPGIQKCGLKVISSIAHSPDALEVLSLEGAVDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCIGTGHLLAKILVSSLQRFKDMAEVQIKGFQTILVILELSV
SFSNLLVHHSFDSVIFHQMSSSIVDQKDQQFLNLCCKCFAKLVMDDELKSVLLERACDQN
NSIMVECLLLLGADANGTKETASLICQVCEKASSPKLVELLLNGGSREQDVRKALAISIG
KGDSQIISLLLRRLALDLANNSICLGGFCIGKIEPSWLGPLFPDKTSNLRKETNIGSTLA
RMVLRYQMKSSLEEGAASGSNGNFPEGVLDKFDEWTFIPDSYVDSVFGQSDDLDSEGSEG
SFLVKRKSNSISVGEFYRDRALQRCSPNLQRHSNSLGPIFDHEDLLRQKRKILSSDDSLR
SSKLQSHMRHSDSISSLASEREYITSLDLSANELRDIDALSQKCSISGHLEHLEKLELHQ
NALTSFPQQLCETLKCLTHLDLHSNKFTSFPYYLLKMNCIANLDVSRNDISHSVVLDPAV
KCPTLKHFNLSYNQLSSFPENLGVVVEKLEQLILEGNKIPEICSPLSLKELKILNLSKNH
ITSLSEDFLEACPKVESFSARMNYLAAMPLLPSSLTSLKLSQNRFTCVPEVILNLPHLRS
LDMSSNEIEYLPSPAHWKSLNLRELLFSFNQISILDLSEKAYVWSRVEKLHLSHNKLKEI
PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELRLNFDFKHIGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLTKTKKSDLGVQSATVGIDVKDWPIQI
RGKGKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVKEN
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGYPK
HPKGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKGSLTRTLQHRIALHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAGIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYG
CAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRHISIPKNFSVECMVATNH
NSKNASIWLGCGHRDKGQLLFLDLNTEKQTSEEVIDSRILCLALVPLPAEKESWIVCGTQ
SGMLLVVNTEDGDKRHNLGKMTDSVTCLYCNPFPKQSKQKNFLLVGTADGNLAIFEDKTV
KCKGAAPLKILNIGNVSTPLMCLSESLNSAEKNIMWGGCGTKLFSFSDDFTIQKLIETKT
NQLFSYAAFSDSNIIAVVVDTALYVAKKNSPFVEVRDKKTEKLCELIDCVHFLKEEMVKV
NAESKHKLSYTGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIIRIIQNFCDSVRVMMT
AQLGSLKNVMLVLGYIRKSTESSQHQKEIQSCLSVWDINLPHEVQNLEKHIEVRKELAEK
MRRVSVE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgtcaggggtgcgaggaggaggacgaggaaactctgaagaagttg
atagtcaggctgaacaatgtccaggaaggaaaacagatagagaccctggtccaaattctg
gaggatatgctggtgttcacgtacgccgaccacgcctccaagttatttcaaggcaaaaaa
gtccacgtgcctgtgttgatcgtcttggacttatatatgagagtcgctagtgtgcagcag
gtgggttggtcacttctttgcaaattgatagaaatctgtccaaatacaatgcaaagctta
atgggacctcaggatattggacatgattgggaagtacttggggttcaccaactgattctt
aaaatgctaacagttcataatgccaacgtaaacctattaacagttgggctgaaggcctta
gatctccttctaacttcaggcaaaatcactttgctgatattggacgaagaaagtgatatt
ttcttgttaatttttgatgccatgcgcacattttcagccaatgatgaagtccagaaactt
ggatgcaaagctttacatgtgctgtttgaaagagtttcagaggagcagcttaccgaattt
gttgagaataaagattatatgatcttgctcaatgcattaaaaaattttaaagatgaagag
gaaattgtgcttcacgtcctgcactgtttacattccctagcaattccttgcaataatgtt
gaagtcctcatgagtggcaacgtcaggtgttataatattgtggtagaagccatgaaaaca
ttccctgtcaatgaaaaggttcaagaagtgagttgttgcttgctccataggcttacatta
ggtaatttttttaatattctggtattaaatgaggtacatgagtttgtggtgaaagccgtg
cggcgatattcagagaacgccacgttacagattgcagcactcagctgtttagcgctcctc
actgagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaatgat
gatgaggaagaggataaattgttctggttggaagcctgttacaaagcattgacatggcat
agaaagaacaagcatgtgcaggaggctgcatgctgggcccttaacaatctccttatgtac
caaagcagtttacatgagaagattggagatgaagatggccagttcccagctcatagggaa
gtgatgctttccatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcaaat
gcattgtcgactctgttagaacaaaacgttaatttcagaaagatcctgttgtccaaagga
atatacctcaatgtactggagttaatgcagaggcatatacattctccagaagttgctgaa
agtggctgtaagatgctaaatcatctctttgaaggaagcaacacgaccctggatacaatg
gcagcagtggcccccaagataataacagttatgaaaagtcatgagacatccttatcagtg
cagctggaggcactcagagctgttttacattttatagttccagggatgtcagaagaatcc
agagaagatactgaatatcaacataagctaaatatggttaaaaaacagtgtttcaagaat
gatattcataaactagtcctagcagctttgaacaagttcattggaaatcctgggattcag
aaatgtgggttgaaagtgatttcctctatagcacattctcctgatgcgctagaagtatta
tccttggaaggtgctgttgattccgtgcttcacacgttgcagatgtatcccgatgaccaa
gagattcaatgtctggggttaagtcttataggatgcttgattacaaagaagaatttatgc
ataggaactgggcatctgctggcaaaaattctggtttccagtttacaacgatttaaggat
atggccgaagtacagattaaaggatttcagacaatcttggtaatactggaattgtcagtg
tctttttccaacctgctggtgcatcattcctttgattccgtgatattccatcagatgtct
tctagtatcgtggatcaaaaggatcaacagtttctaaacctttgttgcaagtgctttgca
aaattagttatggatgacgaattaaaaagtgtgctgctagagagagcatgcgatcagaat
aacagtatcatggttgaatgcttgctcctgttgggagcggacgccaatggaacaaaggag
acagcgtctttaatttgtcaggtatgtgagaaagccagcagtcccaaattggtggaactg
ctactgaatggtggttcccgtgaacaagatgttcggaaggcgctggcgataagcattggg
aaaggtgacagccagatcattagcttacttttaagaagacttgctctggatctggccaat
aatagcatttgccttggaggattttgtataggaaaaattgaaccttcatggcttggtcct
ttatttccagataagacatctaatttaagaaaagaaacaaatataggatccaccctagca
agaatggtgctcagatatcagatgaaaagttctttggaagaaggggcagcctcaggcagc
aatgggaactttcctgaaggagtacttgataaatttgatgaatggaccttcattccagac
tcctatgtggacagtgtttttggtcaaagtgatgacctggatagtgaaggaagtgaaggt
tcatttcttgtgaaaagaaaatccaattcaattagtgtaggagaattttaccgagatcgt
gccttgcagcgttgctcaccaaatttgcaaaggcattccaactcattgggacctattttc
gatcatgaagatttactgaggcaaaagagaaaaatactgtcttcagatgactcactcagg
tcatcaaaacttcaatcccatatgaggcattcagacagcatttcttccctggcttctgag
agagagtatatcacatcattagacctttcagcaaatgaactaagagatattgatgccttg
agccagaaatgctctatcagtggtcatttggagcatcttgaaaagctggagcttcatcag
aatgcactcacgagctttccacaacaactctgtgaaaccctgaagtgtttgacgcatttg
gatttgcacagtaataaatttacatcatttccctattacttgttgaaaatgaattgtatt
gccaacctcgatgtctctcgaaacgacatcagccattcagtagttttggatcctgcagtg
aagtgcccaaccttgaaacactttaacttgtcatataatcagctgtcttcctttcctgag
aaccttggtgttgtggtagagaaattggaacagctcattttagaaggaaataaaatacca
gaaatatgttcccccttaagcctgaaggaactgaagattttaaaccttagtaaaaaccac
attacatcgctatcagaagacttccttgaggcatgtcctaaagtggagagtttcagtgcc
agaatgaattatcttgctgctatgcctcttttgccttcttccctgacaagcctaaaacta
tctcaaaacagatttacatgtgttccagaagtaattttaaatcttccacacttgcgatct
ttagatatgagcagcaatgaaattgagtatctgccgagtcctgcacactggaaatctttg
aacttaagggaactcttgttcagttttaatcagatcagcatcttggacttgagcgaaaaa
gcgtatgtgtggtcaagagtagagaaactacatctttctcataataaactgaaagagatt
cctcccgagattggctgtctcgaaaacctgacctcccttgatgtcagttacaacttggag
ctgagatcctttcctaatgaaatggggaagttaagcaaaatatgggatcttcctttggat
gaactacggcttaattttgattttaaacatataggatgtaaagccaaagacatcataagg
tttcttcaacagcggttaaaaaaggccgtgccctataatcgaatgaagcttatgattgtg
ggaaatactgggagtggtaaaaccaccttattgcagcaactgacaaaaaccaagaagtca
gatcttggggtgcagagcgccacagtaggtatagatgtgaaagactggcctatccaaatt
agaggcaaagggaagaaggacctcattctgaatgtgtgggattttgcaggtcgtgaggaa
ttctacagcactcatccccacttcatgacccaacgagccctctaccttgctgtctatgac
ctcagcaaagggcaggctgaagtggacgccatgaaaccttggctcttcaatataaaggct
cgtgcttcttcttcccctgtgattcttgttggcacacatttggatgtttctgatgaaaag
cagcgcaaagcctgcataagtaaaatcaccaaggaactcttgaacaagcgagggtttcct
gcaataagggattaccactttgtgaatgccactgaggaatctgatgctctggcaaagctt
cggaaaaccatcatcaatgagagtcttaatttcaagatccgagatcagcctgttgttggg
cagctgattccagactgctatgtagaacttgagaaaatcattttatcggagcgtaaaaat
gtgccaattgaatttcctgtaatcgaccggaaacgactattacaactcgtaaaagaaaat
cagctgcagttggatgaaaatgagcttcctcatgcagttcacttcctaaatgaatcaggg
gtacttcttcattttcaagacccagcattgcagttaagtgacttatattttgtggaaccc
aagtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctatccaaaa
catcctaaaggaatcatttcacgtagagatgtggaaaaatttctttcaaagaaaaagaga
tttccgaagaactacatgtcacagtactttaaactcctagaaaaattccagattgccttg
ccaataggagaagaatatttgctggttccaagcagtttgtctgaccacaggcctgtgata
gagcttccccattgtgagaactctgaaattatcattcgactatatgaaatgccttatttt
ccaatgggattttggtccaggttaatcaatcgattacttgaaatttcaccttacatgctt
tcaggaagagaacgagcacttcgtccaaacagaatgtactggcgacaaggcatctacttg
aattggtctcctgaagcttattgtctggtaggatctgaagtcttagacaatcatcctgag
agtttcttaaaaattacagttccttcttgtagaaaaggctgtattcttctgggtcaagtt
gtagaccacattgattctctcatggaagaatggtttcctggactactggagattgatatc
tgtggtgaaggagaaactctgttgaagaaatgggcattatatagttttaatgatggtgaa
gagcatcaaaaaatcttacttgatgacttgatgaagaaagcagaagaaggagaccttcta
gtaaatccagatcaaccaaggctcaccattccaatatctcaaattgctcctgacttaatt
ttggctgacctgcctagaaatattatgttgaataatgatgaattggaatttgaacaagct
cctgagtttctcttaggtgatggcagttttggctctgtttatcgggcagcctatgaaggg
gaagaagtggctgtgaagattttcaataaacatacatcacttagactgttaagacaagag
ctggtggtcctttgccacctccaccaccccagcttaatatctttgctggcggctgggatt
cgtcctcgcatgttggtgatggagttggcctccaagggttcgctggaccgcttgcttcag
caagacaaaggaagtcttaccagaaccctgcagcacaggattgcgctacatgtggctgat
ggcttgagatatctccactcggccatgattatataccgtgacttaaagccccacaacgtg
ctgctcttcaccctgtatcccaatgctggcatcattgcgaagattgcagactacggaatt
gctcagtactgctgtaggatggggataaagacatcggagggcacaccagggtttcgtgca
cctgaagttgctagaggaaatgttatttataaccaacaagctgatgtttattcatttggt
ttactactctatgacattttgacaactggaggtagaatagcagagggtttgaagtttcca
aatgagtttgatgaactggcaatacaaggaaaattacctgatccagttaaagaatatggc
tgtgccccatggcccatggttgagaagttaattaaaaagtgtttgaaggaaaatcctcaa
gaaaggcctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctg
atgaggcatatatcaatacctaaaaactttagcgttgaatgcatggtcgctacaaatcat
aacagcaagaatgcaagcatctggctgggctgtgggcaccgtgacaaaggacagctctta
tttcttgacttaaatacagaaaaacagacttctgaggaagttattgatagtagaatactg
tgcctagctttggtgcctcttcctgcggaaaaggaaagctggatagtgtgtgggacacag
tctggcatgctcctggtcgtcaatacagaagatggggataagagacataaccttggaaag
atgaccgattctgtgacttgcttgtattgcaatccctttcccaagcaaagcaagcaaaaa
aactttcttctggtgggaactgctgatggcaatttagcaatttttgaagataaaactgtt
aagtgtaaaggagccgctcctttgaagatactaaatataggaaatgtcagtactccactg
atgtgtttgagtgaatcgttgaattcagctgaaaaaaacatcatgtggggaggatgtggc
acaaaacttttctcattttctgatgatttcaccattcagaagctcattgagacaaagaca
aatcagctgttttcttatgcagctttcagtgattccaacatcatagcagtggtggtagac
acggctctctacgttgctaagaaaaatagcccatttgtggaagtacgggataagaaaact
gaaaaactctgtgaactaatagactgtgtgcactttttaaaggaggaaatggtaaaagta
aatgcagaatccaaacacaaactatcttacactgggagagtgaaaaccctgtgccttcag
aagaacaccgctctctggataggaactggaggaggccatattttactccttgatctttca
actcgtcgaattatacgtataattcagaatttctgtgactctgtcagagtcatgatgaca
gcacagttaggaagccttaaaaatgtcatgctggttttggggtatatccggaaaagtact
gaaagttcacaacaccaaaaagaaatacaatcttgtttgtctgtctgggacatcaatctt
ccacatgaagtgcaaaacttagaaaaacatattgaagtgagaaaagaattagctgaaaaa
atgagaagagtatctgttgaataa
DBGET
integrated database retrieval system
