Modestobacter italicus: MODMU_5240
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Entry
MODMU_5240 CDS
T02167
Symbol
pdhA
Name
(GenBank) Pyruvate dehydrogenase E1 component, alpha subunit
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mmar
Modestobacter italicus
Pathway
mmar00280
Valine, leucine and isoleucine degradation
mmar00640
Propanoate metabolism
mmar00785
Lipoic acid metabolism
mmar01100
Metabolic pathways
mmar01110
Biosynthesis of secondary metabolites
mmar01210
2-Oxocarboxylic acid metabolism
Module
mmar_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmar00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MODMU_5240 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MODMU_5240 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MODMU_5240 (pdhA)
Enzymes [BR:
mmar01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MODMU_5240 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
CCH90615
UniProt:
I4F4Q2
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All DBs
Position
complement(5225609..5226745)
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AA seq
378 aa
AA seq
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MSTLSQTTEVVDPVPGAGAPHLPGQPDLVQLLTPEGERVEHPDYSLDVSDEELRGLYRDL
ALVRRWDVEATALQRQGELGIWASLLGQEAAQVGAGRALAADDMAFPTYREHGVAWTRGV
DPLHVMSLFRGVDQGGWDPVATNFNLYTVVIGAQTLHATGYAMGLQRDSAESAALAFLGD
GATSQGEVNEAMIWAATFSAPVVFFCQNNQYAISVPIERQSRVPLYQRAAGFGFPGVRVD
GNDVLAVLAVTRAALAAAREGQGPTFIEAFTYRMGAHTTSDDPTRYRLASELEEWKLRDP
IARLKAHLSRSGTADAEFFASVDAEGDELAARIRRGTLEMADPAGTEIFDHVYAEQTPEL
ARQREEFVAYHASFEGEK
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgagcacgctgtcgcagaccaccgaggtggtcgaccccgtacccggggccggcgccccc
cacctgcccggtcaacccgacctggtgcagctgctcaccccggagggcgagcgcgtcgag
caccccgactactccctcgacgtcagcgacgaggagctgcgcgggctgtaccgcgacctc
gccctggtccgccgctgggacgtcgaggccaccgcgctgcagcggcagggcgagctcggc
atctgggcctcgctgctgggccaggaggccgcgcaggtgggcgccggacgcgcgctggcc
gccgacgacatggccttcccgacctaccgcgagcacggcgtcgcctggacccggggcgtc
gacccgctccacgtgatgagcctgttccgcggcgtcgaccagggcggctgggacccggtc
gcgaccaacttcaacctctacaccgtggtcatcggcgcgcagacgctgcacgccaccggc
tacgcgatgggtctgcagcgcgacagcgcggagagcgcggcgctggccttcctcggcgac
ggcgccaccagccagggcgaggtcaacgaggcgatgatctgggcggcgacgttctccgca
ccggtcgtcttcttctgccagaacaaccagtacgcgatcagcgtgccgatcgagcggcag
tcccgggtgccgctgtaccagcgcgccgccgggttcggcttccccggcgtccgagtcgac
ggcaacgacgtcctcgccgtcctcgcggtcacccgggcggcgctcgccgcggcccgggag
ggccagggtccgaccttcatcgaggccttcacctaccggatgggcgcgcacaccacctcc
gacgacccgacccgctaccggctggccagcgagctggaggagtggaagctgcgcgacccg
atcgcccggctcaaggcccacctgtcccgctccggcacggccgacgcggagttcttcgcc
tccgtcgacgccgagggcgacgagctggcggcccggatccgccggggcacgctggagatg
gccgacccggccggcaccgagatcttcgaccacgtctacgccgagcagacccccgagctg
gcccgccagcgcgaggagttcgtggcctaccacgccagcttcgagggggagaagtga
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